During Sepsis and COVID-19, the Pro-Inflammatory and Anti-Inflammatory Responses Are Concomitant [0.03%]
脓毒症和COVID-19中存在共存的促炎与抗炎反应
Jean-Marc Cavaillon
Jean-Marc Cavaillon
The most severe forms of COVID-19 share many features with bacterial sepsis and have thus been considered to be a viral sepsis. Innate immunity and inflammation are closely linked. While the immune response aims to get rid of the infectious...
COVID-19, Coronavirus Vaccines, and Possible Association with Lipschütz Vulvar Ulcer: A Systematic Review [0.03%]
COVID-19、新型冠状病毒疫苗与Lipschütz外阴溃疡的可能关联：系统评价
Stefano A Vismara,Andrea Ridolfi,Pietro B Faré et al.
Stefano A Vismara et al.
Lipschütz genital ulcer is a self-limited, non-sexually acquired disorder characterized by the sudden onset of a few ulcers. A primary Epstein-Barr virus infection is currently considered the most recognized cause. Recent reports document ...
Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity [0.03%]
吗替麦考酚酯在自身免疫性疾病治疗中的应用展望
Rithika Bhat,Antonio Tonutti,Suraj Timilsina et al.
Rithika Bhat et al.
Before becoming a cornerstone in the treatment of numerous immune-mediated diseases, mycophenolate mofetil (MMF) was first introduced as an immunosuppressive agent in transplant immunology and later received the attention of rheumatologists...
Food Allergy Labeling Laws: International Guidelines for Residents and Travelers [0.03%]
国际食品过敏标签法规指南
Francesca Chang,Lauren Eng,Christopher Chang
Francesca Chang
The prevalence of food allergies varies by country, as does each country's food allergen labeling. While labeling laws may vary by country, most follow the Codex Alimentarius. Even developing countries have some degree of labeling guideline...
Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature [0.03%]
抗TNFα治疗轴向脊柱关节炎患者的单细胞分析：实验数据与文献回顾
Zhi-Bin Zhao,Zhen-Hua Bian,Zhang-Mei Lin et al.
Zhi-Bin Zhao et al.
Axial spondyloarthritis (Ax-SpA) is a chronic inflammatory disease that predominantly affects the axial joints and is most common in young men. However, the precise immune cell subset involved in Ax-SpA remains unclear. Our study characteri...
Zhouxian Pan,Yimin Dai,Nicole Akar-Ghibril et al.
Zhouxian Pan et al.
Air pollution is associated with multiple health problems worldwide, contributing to increased morbidity and mortality. Atopic dermatitis (AD) is a common allergic disease, and increasing evidence has revealed a role of air pollution in the...
Tihong Shao,Ronald Hsu,Camelia Hacein-Bey et al.
Tihong Shao et al.
The human gastrointestinal tract houses an enormous microbial ecosystem. Recent studies have shown that the gut microbiota plays significant physiological roles and maintains immune homeostasis in the human body. Dysbiosis, an imbalanced gu...
Frederick Gibson,Ailish Hanly,Nicole Grbic et al.
Frederick Gibson et al.
Epigenetics is the study of heritable, reversible gene expression patterns that do not originate from alterations in the DNA sequence. Epigenetic modifications influence gene expression patterns and include DNA methylation, histone modifica...
New Mechanistic Advances in FcεRI-Mast Cell-Mediated Allergic Signaling [0.03%]
新型FcεRI介导的肥大细胞信号通路机制研究进展
Yang Li,Patrick S C Leung,M Eric Gershwin et al.
Yang Li et al.
Mast cells originate from the CD34+/CD117+ hematopoietic progenitors in the bone marrow, migrate into circulation, and ultimately mature and reside in peripheral tissues. Microbiota/metabolites and certain immune cells (e.g., Treg cells) pl...
Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point [0.03%]
毛囊黑素细胞是斑秃自身免疫的触发点
Bo Xie,Jiayi Sun,Xiuzu Song
Bo Xie
Alopecia areata (AA) is characterized by common non-scarring alopecia due to autoimmune disorders. To date, the specific pathogenesis underlying AA remains unknown. Thus, AA treatment in the dermatological clinic is still a challenge. Numer...