Chih-Chao Chiang,Wei-Jen Cheng,Joseph Renz Marion Santiago Dela Cruz et al.
Chih-Chao Chiang et al.
Neutrophils have a critical role in inflammation. Recent studies have identified their distinctive presence in certain types of atopic dermatitis (AD), yet their exact function remains unclear. This review aims to compile studies elucidatin...
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy [0.03%]
过敏原检测：眼部过敏症指征、操作程序和局限性的综述
Anahita Kate,Swapna S Shanbhag,Jyothirmai Gattu et al.
Anahita Kate et al.
Allergen-based diagnostics are essential in the management algorithm of allergic diseases. Unlike systemic allergy, where the indications and interpretation of these diagnostic modalities are well established, their utility in ocular allerg...
Tiantian Deng,Zihan Wang,Qishun Geng et al.
Tiantian Deng et al.
The role of abnormal epigenetic modifications, particularly DNA methylation, in the pathogenesis of autoimmune rheumatic diseases (ARDs) has garnered increasing attention. Lymphocyte dysfunction is a significant contributor to the pathogene...
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases [0.03%]
单细胞测序：自身免疫疾病中细胞异质性的高分辨率分析
Xuening Tang,Yudi Zhang,Hao Zhang et al.
Xuening Tang et al.
Autoimmune diseases (AIDs) are complex in etiology and diverse in classification but clinically show similar symptoms such as joint pain and skin problems. As a result, the diagnosis is challenging, and usually, only broad treatments can be...
Albert C Chong,Francisco José Navarro-Triviño,Malcolm Su et al.
Albert C Chong et al.
Head and neck dermatitis (HND) is a form of atopic dermatitis (AD) that affects the seborrheic areas of the body and causes greater quality of life detriments than other types of AD. HND can be challenging to treat since first-line topical ...
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy [0.03%]
哮喘中的CAR-NKT细胞：NKT作为有前景的CAR治疗细胞
Mohadeseh Mohammad Taheri,Fatemeh Javan,Mohadeseh Poudineh et al.
Mohadeseh Mohammad Taheri et al.
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory disorders like asthma. Activating iNKT induces increasing IFN-γ, TGF-β, IL-2, and IL-10 potentially suppressing all...
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections [0.03%]
肠道产生的短链脂肪酸与巨噬细胞调控：探讨其在肺部真菌感染治疗中的潜力
Qian Xie,Qinhui Li,Hong Fang et al.
Qian Xie et al.
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly macrophages. This review explores the potential therapeutic applications of SCFAs in pulmonary fungal infections, a cri...
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome [0.03%]
特应性皮炎和银屑病：代谢和微生物群的相似性和差异性
Yihui Chen,Cong Peng,Lei Zhu et al.
Yihui Chen et al.
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical features, including symptoms of pruritus and pain, scaly lesions, and histologically, acanthosis and hyperkeratosis. Meanwhi...
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics [0.03%]
纤维细胞：自身免疫性和炎症性皮肤病治疗的新靶点
Xiaoyun Chen,Yutong Wu,Sujie Jia et al.
Xiaoyun Chen et al.
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin's structure by producing extracellular matrix and other elements. Recent research illuminated that fibroblasts can respond to ex...
Brian Hom,Natalie K Boyd,Benjamin N Vogel et al.
Brian Hom et al.
Down syndrome is the most common genetic cause of intellectual disability and has previously been associated with a variety of autoimmune disorders affecting multiple organ systems. The high prevalence of autoimmune disease, in conjunction ...