Furry Animal Allergy: Lipocalins, Serum Albumins, and Secretoglobins-Cross-Reactivity, Diagnosis, and Management Strategies [0.03%]
动物皮毛过敏:脂钙蛋白、血清白蛋白和分泌 globulin-交叉反应、诊断与管理策略
Weronika Gromek,Natalia Kołdej,Marcin Kurowski et al.
Weronika Gromek et al.
Furry animals are familiar companions in modern society. Despite multiple beneficial roles in economic and social contexts, they can be the source of allergenic compounds. Moreover, research indicates that these allergens could be detected ...
Gian Marco Pace,Luca Canali,Domenico Villari et al.
Gian Marco Pace et al.
The aim of this study is to analyze data from all cases of Susac syndrome that have been published in the literature. This study was conducted in conformity with the PRISMA statement. A systematic review and survival analysis was performed ...
Circadian Clock Disruption and Non-type 2 Asthma: A Hypothesis-Driven Perspective on Immune, Epithelial, and Steroid Response [0.03%]
昼夜节律紊乱与非典型哮喘:从免疫、上皮和激素反应角度提出的假说驱动观点
Haohua Huang,Xiaoxiao Jiang,Qian Du et al.
Haohua Huang et al.
Asthma is a major chronic non-communicable respiratory disease, affecting over 300 million individuals globally, with an adult prevalence of 4.3%. Despite advances in individualized treatment, a subset of patients, particularly those with n...
Adriano Martínez Villarreal,Valeria Grattz Lamadrid,Andrés Sanchez et al.
Adriano Martínez Villarreal et al.
Aquaporins (AQPs) are transmembrane proteins that facilitate the transport of water and small solutes across cell membranes. Their expression in organs such as the skin, lungs, gastrointestinal tract, and immune system has been implicated i...
Efficacy and Safety of Biologics for Systemic Lupus Erythematosus (SLE): A Systematic Review and Network Meta-Analysis [0.03%]
生物制剂治疗系统性红斑狼疮疗效和安全性的系统评价和网状Meta分析
Ziyan Ding,Hui Zhang,Fan Huang et al.
Ziyan Ding et al.
This study aimed to use Bayesian network meta-analysis to compare the efficacy and safety of biologics for systemic lupus erythematosus (SLE). A comprehensive and systematic search of electronic databases (PubMed, Medline, Cochrane Library,...
UHRF1 in Immune Regulation and Diseases: Mechanisms and Therapeutic Implications [0.03%]
UHRF1在免疫调控及疾病中的作用机制及其治疗意义
Tingyue Guo,Yihui Ruan,Bo Wu et al.
Tingyue Guo et al.
As a key epigenetic regulator, E3 ubiquitin-ligase ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) is essential for maintaining genomic stability. The aberrant activation of UHRF1 has been strongly implicated in cancer progr...
Residential Proximity to Major Roadways and Risk of Allergic Respiratory Outcomes: A Systematic Review and Meta-analysis [0.03%]
关于居住在主干道路附近与过敏性呼吸道结果风险之间关系的系统评价和meta分析
Qinchi Yu,Zihao Guo,Lijun Bai et al.
Qinchi Yu et al.
With the acceleration of global urbanization, residential proximity to major roadways (RPMR) has been recognized as a significant threat to public health, while the association between road proximity and risks of allergic respiratory outcom...
Neurological Complications in Inborn Errors of Immunity: A Scoping Review of Clinical Spectrum, Pathophysiological Mechanisms, and Therapeutic Strategies [0.03%]
先天性免疫缺陷的神经系统并发症:临床谱系、病理生理机制和治疗策略的综述性研究
Ningkun Xiao,Xinlin Huang,Linzi Chen et al.
Ningkun Xiao et al.
Inborn errors of immunity (IEIs) are traditionally viewed as monogenic disorders of the immune system, but mounting evidence indicates that they often have underappreciated impacts on the nervous system. We review the emerging intersection ...
The c.64 + 2 T > A Founder Variant Hits Home: Report on 14 Patients Expands the Phenotypic Landscape of Inherited ARPC1B Deficiency - a Comparative Analysis [0.03%]
致病性ARPC1B突变体c.64+2T>A破译记:对14例患者的报道拓展了遗传性ARPC1B缺陷表型图谱-比较分析
Dharmagat Bhattarai,Aaqib Zaffar Banday,Pratap Kumar Patra et al.
Dharmagat Bhattarai et al.
Background: Inherited ARPC1B deficiency (ARPC1BD) is a rare autosomal recessive inborn error of immunity that manifests with allergic, infective, and autoimmune/inflammatory features. Only about three dozen patients with ...
Atopic Dermatitis beyond Eczema: A Review on its Systemic Impact through Pruritus and Associated Comorbidities [0.03%]
特应性皮炎的系统性影响:通过瘙痒和相关共病超越湿疹——综述
Alvaro Prados-Carmona,Husein Husein-ElAhmed,Francisco J Navarro-Triviño et al.
Alvaro Prados-Carmona et al.
Atopic dermatitis is the most prevalent chronic inflammatory skin disease, traditionally recognized for its defining eczematous lesions. However, the implications of atopic dermatitis extend far beyond eczema itself. Increasing understandin...