Oncocytes, oxyphils, Hürthle, and Askanazy cells: morphological and molecular features of oncocytic thyroid nodules [0.03%]
甲状腺肿物的滤泡上皮增生的形态及分子特征：oncocytosis,Hürthle细胞和oxyphil细胞的区别
Ozgur Mete,Sylvia L Asa
Ozgur Mete
Our understanding of oncocytic change in thyroid nodules is evaluated in light of the recent progress in understanding the mitochondrial DNA, its mutations, and somatic mutations that affect mitochondrial function. These changes are largely...
Absence of BRAF, NRAS, KRAS, HRAS mutations, and RET/PTC gene rearrangements distinguishes dominant nodules in Hashimoto thyroiditis from papillary thyroid carcinomas [0.03%]
桥本甲状腺炎优势结节与乳头状癌的区别在于BRAF、NRAS、KRAS、HRAS基因突变及RET/PTC重排阴性
Peter M Sadow,Michael C Heinrich,Christopher L Corless et al.
Peter M Sadow et al.
Dominant nodules within Hashimoto thyroiditis (HT) may present with unique morphological features that overlap with but are not diagnostic of papillary thyroid carcinoma (PTC). Activating BRAF point mutations, RAS aberrations, and RET rearr...
Poorly differentiated thyroid carcinoma: 5 years after the 2004 WHO classification of endocrine tumours [0.03%]
甲状腺未分化癌：2004年内分泌肿瘤WHO分类后的5年回顾
Marco Volante,Mauro Papotti
Marco Volante
Poorly differentiated thyroid carcinoma (PDTC) was originally described in 1983 but included in the WHO classification of thyroid tumours in the 2004 edition, only. The diagnostic problems encountered in the 5 years of application of the WH...
Familial cervical paragangliomas with lymph node metastasis expressing somatostatin receptor type 2A [0.03%]
家族性伴有淋巴结转移的颈动脉体瘤表达生长抑素受体2A型
Noriko Kimura,Hiroo Tateno,Shigeru Saijo et al.
Noriko Kimura et al.
We report a case of familial, bilateral cervical paragangliomas (PGs) with lymph node metastasis. Patient I-1 is a 56-year-old man with a right carotid body tumor and a left vagal PG. Patient II-1 is a 29-year-old woman and the daughter of ...
Analysis of IMP3 expression in normal and neoplastic human pituitary tissues [0.03%]
人垂体正常与肿瘤组织中IMP3的表达分析
Alberto Righi,Shuya Zhang,Long Jin et al.
Alberto Righi et al.
Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein highly expressed in fetal tissue and malignant tumors but rarely found in adult benign tissues. In various tumors, IMP3 expression is correlated with increa...
RAS mutation-positive follicular variant of papillary thyroid carcinoma arising in a struma ovarii [0.03%]
卵巢甲状腺肿中发生带有RAS突变的滤泡型乳头状甲状腺癌
Christopher Coyne,Yuri E Nikiforov
Christopher Coyne
Struma ovarii is an ovarian mature teratoma composed exclusively or predominantly of thyroid tissue. Malignant transformation of struma ovarii is rare and poorly understood, although this process is thought to be similar to carcinogenesis i...
Case Reports
Endocrine pathology. 2010 Jun;21(2):144-7. DOI:10.1007/s12022-009-9097-8 2010
Solid cell nests in Hashimoto's thyroiditis sharing features with papillary thyroid microcarcinoma [0.03%]
桥本甲状腺炎中具有乳头状甲状腺微小癌特征的实性细胞巢
Sofia Asioli,Lori A Erickson,Ricardo V Lloyd
Sofia Asioli
Solid cell nests (SCN) associated with Hashimoto's thyroiditis may show some atypical nuclear features including prominent nuclear grooves, enlarged overlapping nuclei and nuclear clearing. These features are sometimes mistaken for papillar...
Comparative Study
Endocrine pathology. 2009 Winter;20(4):197-203. DOI:10.1007/s12022-009-9095-x 2009
Clinicopathological characterization of TSH-producing adenomas: special reference to TSH-immunoreactive but clinically non-functioning adenomas [0.03%]
促甲状腺激素分泌瘤的临床病理特征研究及对免疫阳性但无功能腺瘤的讨论
Elaine Lu Wang,Zhi Rong Qian,Shozo Yamada et al.
Elaine Lu Wang et al.
Thyrotropin (thyroid-stimulating hormone (TSH))-producing pituitary adenomas have been known to be quite variable in clinical features covering from typical functioning TSH-producing adenomas (FTSHomas) associated with hyperthyroidism to cl...
Runjan Chetty,Ihab El-Shinnawy
Runjan Chetty
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently....
Adequacy and diagnostic accuracy of aspiration vs. capillary fine needle thyroid biopsies [0.03%]
抽吸与毛细血管针活检在甲状腺结节诊断中的准确性及充分性比较研究
Gisah Amaral de Carvalho,Gilberto Paz-Filho,Teresa C Cavalcanti et al.
Gisah Amaral de Carvalho et al.
Thyroid nodules can be biopsied by fine needle aspiration (FNA) or fine needle capillary (FNC) biopsies. However, there is controversy on whether one technique is superior to another. In a randomized cytopathologist-blinded cross-sectional ...
Randomized Controlled Trial
Endocrine pathology. 2009 Winter;20(4):204-8. DOI:10.1007/s12022-009-9092-0 2009