Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumor [0.03%]
以黏液性间质为特征的非典型类癌——肺神经内分泌肿瘤的一种此前未被报道的变异型
Nazarena Nannini,Federica Bertolini,Alberto Cavazza et al.
Nazarena Nannini et al.
Carcinoid tumors of the lung may show several growth patterns and cell types. We report here a previously undescribed case of primary pulmonary atypical carcinoid with prominent mucinous stroma, an exceedingly rare variant of carcinoid tumo...
Case Reports
Endocrine pathology. 2010 Jun;21(2):120-4. DOI:10.1007/s12022-010-9115-x 2010
Solitary fibrous tumor of the adrenal gland with unusual immunophenotype: a potential diagnostic problem and a brief review of endocrine organ solitary fibrous tumor [0.03%]
具有不典型免疫表型的肾上腺孤立性纤维瘤肿瘤：潜在的诊断问题及内分泌器官孤立性纤维瘤肿瘤简述
Yong Howe Ho,Wai Ming Yap,Khoon Leong Chuah
Yong Howe Ho
Solitary fibrous tumor was initially thought to be a pleura-based tumor. However, over the last two decades, its involvement in a variety of extrapleural sites gained recognition. Nonetheless, a primary involvement of the endocrine organs i...
Mutational and immunohistochemical study of the PI3K/Akt pathway in papillary thyroid carcinoma in Greece [0.03%]
希腊乳头状甲状腺癌的磷脂酰肌醇3-激酶/蛋白激酶B途径的突变和免疫组化研究
Elias Sozopoulos,Helen Litsiou,Gerassimos Voutsinas et al.
Elias Sozopoulos et al.
PI3K/Akt signaling pathway plays critical role in many cell processes. There is indication that enhanced activation of PI3K/Akt cascade is implicated in thyroid tumors. Aim of this study was to evaluate the mutational status and expression ...
Virginia A LiVolsi
Virginia A LiVolsi
Tall cell variant of papillary thyroid carcinoma is an aggressive form of thyroid cancer with a significant mortality. This review describes the pathology of this variant, compares it to its pathologic mimics and discusses its clinical path...
Determination of cell proliferation using Mcm2 antigen and evaluation of apoptosis and TGF-beta1 expression in GH-secreting or clinically nonfunctioning pituitary adenomas [0.03%]
应用Mcm2抗原检测细胞增殖并评估生长激素分泌或无功能垂体腺瘤的凋亡和TGF-β1表达
Cristina Micheletto Dallago,Ligia Maria Barbosa-Coutinho,Nelson Pires Ferreira et al.
Cristina Micheletto Dallago et al.
Pituitary adenomas (PA) occasionally show aggressive behavior, with invasion of the surrounding tissues. The identification of markers able to recognize aggressive PA in early stages remains a challenge. We aimed to determine the expression...
Anti-cytokeratin CAM 5.2 is specific for K8 and to a lesser extent for the closely related K7, but shows no reactivity with K18 or K19: comment on: "keratin expression in endocrine organs and their neoplasms" Endocr Pathol. 2009 Spring; 20(1):1-10 [0.03%]
抗细胞角蛋白CAM 5.2抗体仅对K8有较强特异性，而对与之亲缘关系相近的K7则呈现较弱特异性，但不识别K18或K19：关于"内分泌器官及其肿瘤中的细胞角蛋白表达"一文的述评《内分泌病理学》. 2009年春季; 20(1):1-10
Pin-Jie Chen,Jeng-Dong Hsu,Chih-Ping Han
Pin-Jie Chen
Somatostatin-producing atypical null cell adenoma manifesting as severe hypopituitarism and rapid deterioration--case report [0.03%]
一种产生生长抑素的非典型无细胞腺瘤表现为严重的垂体功能减退及病情迅速恶化-病例报告
Yoshikazu Ogawa,Mika Watanabe,Teiji Tominaga
Yoshikazu Ogawa
Atypical adenoma has an aggressive biological character, invades the surrounding structures, and grows rapidly. Morphological malignant findings such as increasing cellularity and nuclear atypism are not involved in this entity, but some ca...
Case Reports
Endocrine pathology. 2010 Jun;21(2):130-4. DOI:10.1007/s12022-010-9110-2 2010
Pituitary adenomas that show a faint GH-immunoreactivity but lack fibrous body: Pit-1 adenoma with endocrinologically low activity [0.03%]
生长激素染色淡阳性但缺乏纤维体的垂体腺瘤：内分泌活性低的Pit-1腺瘤
Akiko Yoneda,Toshiaki Sano,Shozo Yamada et al.
Akiko Yoneda et al.
Growth hormone (GH)-producing pituitary adenomas have been classified into densely and sparsely granulated adenomas. The latter are chromophobic with weak GH-positivity and characteristically possess fibrous body (FB), aggregation of cytoke...
The encapsulated follicular variant of papillary thyroid carcinoma: back to the drawing board [0.03%]
包膜滤泡型乳头状甲状腺癌：重新审视
Juan Rosai
Juan Rosai
The encapsulated follicular variant of papillary carcinoma has become one of the most common diagnoses in thyroid tumor pathology. However, serious issues remain regarding the reproducibility of the diagnosis, its position in the scheme of ...
A double pituitary adenoma presenting as a prolactin-secreting tumor with partial response to medical therapy. Case report [0.03%]
垂体双腺瘤以泌乳素分泌肿瘤形式表现并部分接受药物治疗的病例报告
Claire I Coiré,Harley S Smyth,Dominic Rosso et al.
Claire I Coiré et al.
Double pituitary adenomas are difficult to recognize pre-operatively as only a single mass may be appreciated on imaging. We present herein a giant prolactin-secreting pituitary adenoma in a middle-aged man that had responded partially to d...