The frequency of selected polymorphic variants of the RET gene in patients with medullary thyroid carcinoma and in the general population of central Poland [0.03%]
选择性多态性变异体在甲状腺髓样癌患者和波兰中部一般人群中的RET基因频率分析
Maria Sromek,Malgorzata Czetwertyńska,Elzbieta Skasko et al.
Maria Sromek et al.
The object of this work was to compare the frequency of three polymorphic changes in the RET proto-oncogene: L769L, S836S, and S904S in patients with medullary thyroid carcinoma (MTC; n = 246) and in the general population (n = 420 for sing...
Features of papillary thyroid microcarcinoma in the presence and absence of lymphocytic thyroiditis [0.03%]
淋巴细胞性甲状腺炎存在和不存在时乳头状甲状腺微小癌的特征
Hee Sung Kim,Yoon Jung Choi,Ji-Sup Yun
Hee Sung Kim
It is known that the prevalence of lymphocytic thyroiditis (LT) is higher in patients with papillary thyroid carcinoma (PTC), that gender influences this association, and that certain features of PTC occur more frequently in patients who al...
MGMT immunoexpression in silent subtype 3 pituitary adenomas: possible therapeutic implications [0.03%]
沉默型3垂体腺瘤中的MGMT免疫表型及其可能的治疗意义
Michael E Fealey,Bernd W Scheithauer,Eva Horvath et al.
Michael E Fealey et al.
The objective of the study was to assess O(6)-methylguanine-DNA methyltransferase (MGMT) immunoreactivity in pituitary adenomas of silent subtype 3 as a potential indicator of temozolomide susceptibility. The Mayo Clinic Anatomic Pathology ...
Matteo Fassan,Federico Rea,Roberto Clemente et al.
Matteo Fassan et al.
Carolina Cristina,María Inés Perez-Millan,Guillermina Luque et al.
Carolina Cristina et al.
Pituitary tumors are usually less vascularized than the normal pituitary, and the role of angiogenesis in these adenomas is contentious. Appraisal of microvascular density and expression of the potent angiogenic vascular endothelial growth ...
Parafibromin and APC as screening markers for malignant potential in atypical parathyroid adenomas [0.03%]
辅助腺瘤恶性潜能筛查标志物的研究进展
C Christofer Juhlin,Inga-Lena Nilsson,Kenth Johansson et al.
C Christofer Juhlin et al.
The identification of parathyroid carcinomas is based upon histopathological criteria in which an invasive growth pattern or distant metastasis is demonstrated. A dilemma arises when tumours present with atypical histopathological features ...
Wahiba Sakly,Amani Mankaï,Nabil Sakly et al.
Wahiba Sakly et al.
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described in many autoimmune diseases in which there is an increased intestinal permeability. Also in type 1 diabetes (T1D), there is an increased intestinal permeability. Since no d...
Synchronous metastatic medullary and papillary thyroid carcinomas in a patient with germline RET mutation: case report, molecular analysis, and implications for pathogenesis [0.03%]
伴RET胚系突变的患者出现同步性髓样癌和乳头状癌：病例报告、分子分析及其对发病机制的影响
Christopher Griffith,Shengle Zhang,Sanjay Mukhopadhyay
Christopher Griffith
The occurrence of medullary thyroid carcinoma (MTC) in patients with germline RET mutation is well established, but the occasional occurrence of papillary thyroid carcinoma (PTC) in this setting remains unexplained. We report a case of sync...
Case Reports
Endocrine pathology. 2010 Jun;21(2):115-9. DOI:10.1007/s12022-010-9117-8 2010
Lymphatic vessel density and VEGF-C expression are significantly different among benign and malignant thyroid lesions [0.03%]
良性与恶性甲状腺结节的淋巴管密度和VEGF-C表达差异显著性研究
Eduardo Anselmo Garcia,Kleber Simões,Alda Wakamatsu et al.
Eduardo Anselmo Garcia et al.
Thyroid cancer is the most frequent endocrine neoplasia worldwide. The route for metastasis and loco-regional invasion preferentially occurs by lymphatic vessels. For this reason, the assessment of lymphatic vessel density (LVD) is supposed...
Universal markers of thyroid malignancies: galectin-3, HBME-1, and cytokeratin-19 [0.03%]
甲状腺恶性肿瘤的广谱标志物：galectin-3、HBME-1和cytokeratin-19
Figen Barut,Nilufer Onak Kandemir,Sibel Bektas et al.
Figen Barut et al.
Difficulties in diagnosis of thyroid lesions, even with histologic analysis, are well known. This study has been carried on to evaluate the role of immunohistochemical markers including galectin-3, Hector Battifora mesothelial cell-1 (HBME-...