Changes associated with percutaneous ethanol injection in the treatment of thyroid nodules [0.03%]
经皮乙醇注射治疗甲状腺结节的影像学变化分析
Gianna Carla Alberti Schrut,Fabíola Yukiko Miasaki,Gilberto Paz-Filho et al.
Gianna Carla Alberti Schrut et al.
Percutaneous ethanol injection (PEI) is an alternative therapy for thyroid nodules (TN). However, some concern is raised on its carcinogenic effects. To evaluate the cytological and clinical changes caused by PEI in patients with benign TN....
Uncommon GNAQ, MMP8, AKT3, EGFR, and PIK3R1 mutations in thyroid cancers [0.03%]
罕见的GNAQ、MMP8、AKT3、EGFR和PIK3R1突变在甲状腺癌中出现
Avaniyapuram Kannan Murugan,Jianli Dong,Jingwu Xie et al.
Avaniyapuram Kannan Murugan et al.
Frequent mutations in the GNAQ, MMP8, Akt3, EGFR, and PIK3R1 genes have been reported in human cancers but mostly have not been well examined in thyroid cancer. Selected exons of GNAQ, MMP8, AKT3, EGFR, and PIK3R1 genes were sequenced in va...
Cushing's syndrome due to a pancreatic neuroendocrine tumor metastatic to the ovaries: a clinicopathological description of a case [0.03%]
由胰腺神经内分泌肿瘤转移至卵巢引起的库欣综合征：一例临床病理报告
Stefano La Rosa,Alessandro Marando,Fabio Ghezzi et al.
Stefano La Rosa et al.
We report the case of a 36-year-old woman with Cushing's syndrome caused by a malignant unresectable neuroendocrine carcinoma of the pancreas that developed bilateral ovarian metastases 7 years after diagnosis. In November 2001, because of ...
Malignant adrenal rest tumor of the retroperitoneum producing adrenocortical steroids [0.03%]
后腹膜恶性肾上腺残余肿瘤产生肾上腺皮质类固醇
Yuri Akishima-Fukasawa,Aya Yoshihara,Yukio Ishikawa et al.
Yuri Akishima-Fukasawa et al.
We present a case of a malignant adrenal rest tumor arising from the retroperitoneum with Cushing's syndrome in a 31-year-old female. Her serum cortisol and dehydroepiandrosterone sulfate levels were elevated, while adrenocorticotropic horm...
Case Reports
Endocrine pathology. 2011 Jun;22(2):112-7. DOI:10.1007/s12022-011-9152-0 2011
Identification of de novo germline mutations in the HRPT2 gene in two apparently sporadic cases with challenging parathyroid tumor diagnoses [0.03%]
在两例具有挑战性的甲状旁腺肿瘤诊断的散发病例中鉴定出HRPT2基因从头生殖细胞新突变
Branca Maria Cavaco,Rita Santos,Ana Félix et al.
Branca Maria Cavaco et al.
The diagnosis of parathyroid carcinomas is often difficult. HRPT2 mutations have been identified in familial [hyperparathyroidism-jaw tumor (HPT-JT) syndrome] and sporadic parathyroid carcinomas, supporting that HRPT2 mutations may confer a...
Case Reports
Endocrine pathology. 2011 Mar;22(1):44-52. DOI:10.1007/s12022-011-9151-1 2011
Sahar Al-Haddad,Rafael Fandino,Bernd W Scheithauer et al.
Sahar Al-Haddad et al.
We report the case of a 45-year-old Colombian female with a 3-month history of headache, anorexia, fatigue, and diplopia in addition to left facial nerve palsy 2 weeks prior to presentation. On examination, visual fields and fundi were norm...
Somatostatin and dopamine receptor profile of gastroenteropancreatic neuroendocrine tumors: an immunohistochemical study [0.03%]
胃肠胰神经内分泌肿瘤的生长抑素和多巴胺受体谱系：一项免疫组化研究
Evanthia Diakatou,Gregory Kaltsas,Michail Tzivras et al.
Evanthia Diakatou et al.
Somatostatin and its synthetic analogs act through five specific somatostatin receptors (sstr1-5), found on the cell membrane of various tumors, including endocrine ones. Dopamine--a known neurotransmitter--acts through five membranous dopa...
Peggy Lu Nguyen,David M Poetker,Eduardo Zambrano
Peggy Lu Nguyen
Hemangiomas are benign vascular tumors that are most commonly found superficially in the head and neck. Cavernous hemangiomas are located in deeper structures and have been reported in a variety of endocrine tumors. However, parathyroid hem...
Annalisa Pianta,Cinzia Puppin,Nadia Passon et al.
Annalisa Pianta et al.
Nucleophosmin (NPM) is a multifunctional nucleolar protein that, depending on the context, can act as oncogene or tumour suppressor. Mutations of the NPM1 gene induce delocalization of NPM in acute myeloid leukaemia. Differently, in solid t...
Granular cell tumour of the thyroid gland: a case report and review of the literature [0.03%]
甲状腺颗粒细胞瘤一例并文献复习
Meera Bowry,Bernice Almeida,Jean-Pierre Jeannon
Meera Bowry
Granular cell tumours of the thyroid gland are rare, with only six previously reported cases in the English literature. Current histological, immunohistochemical and electron microscopic evidence favours a neural/Schwannian relationship. A ...