Diagnostic Evaluation of Anaplastic Thyroid Carcinoma in Core Biopsy Specimens: Morphologic, Immunohistochemical, Molecular, and Therapeutic Considerations [0.03%]
甲状腺核心活检标本中诊断性评估间变性甲状腺癌的形态学、免疫组化、分子及治疗相关因素的考量
Maria Cristina Riascos,Justine A Barletta
Maria Cristina Riascos
Although a diagnosis of anaplastic thyroid carcinoma (ATC) can be rendered on fine needle aspiration (FNA), a core needle biopsy is often performed to provide sufficient material for immunohistochemical and molecular analysis. Rendering an ...
DICER1-Related Pediatric Thyroid Neoplasm with Follicular and Morular Growth: A Tumor that Did Not Read the Textbook [0.03%]
Dicer1相关儿童甲状腺肿瘤的滤泡和母细胞型生长：一个没有遵循教科书的肿瘤
José Manuel Cameselle-Teijeiro,Sangeeta Verma,Anthony Penn et al.
José Manuel Cameselle-Teijeiro et al.
Thyroid lesions associated with DICER1 syndrome include multifocal hyperplastic and benign neoplastic proliferations (follicular nodular disease) with characteristic macrofollicular and/or intrafollicular centripetal papillary growth patter...
Case Reports
Endocrine pathology. 2025 Sep 2;36(1):31. DOI:10.1007/s12022-025-09874-z 2025
Progression of Follicular Thyroid Carcinomas to Anaplastic Thyroid Carcinomas: Molecular and Clinicopathologic Characteristics with Comparison to Papillary Thyroid Carcinoma-Derived Anaplastic Thyroid Carcinomas [0.03%]
滤泡性甲状腺癌进展为间变性甲状腺癌：分子及临床病理特征并与乳头状甲状腺癌来源的间变性甲状腺癌进行比较
Toru Odate,Tetsuo Kondo,Ryohei Katoh et al.
Toru Odate et al.
Although anaplastic thyroid carcinomas (ATCs) typically arise from papillary thyroid carcinomas (PTCs), follicular thyroid carcinomas (FTCs) can also progress to ATCs; however, histologically confirmed FTC-derived ATCs are relatively uncomm...
Comparative Study
Endocrine pathology. 2025 Sep 1;36(1):30. DOI:10.1007/s12022-025-09875-y 2025
Exploring Intratumoral Heterogeneity in Mixed Neuroendocrine-Nonneuroendocrine Neoplasms with Spatial Transcriptomics: Even More Diverse Than Anticipated [0.03%]
空间转录组学探索混合神经内分泌肿瘤内的异质性：比预期的更加多样化
Annika Weiß,Julia Teply-Szymanski,Maxime Schmitt et al.
Annika Weiß et al.
Mixed neuroendocrine-nonneuroendocrine neoplasms (MiNEN) are usually highly aggressive tumors characterized by marked histological heterogeneity, most commonly represented by mixed adenocarcinoma and poorly differentiated neuroendocrine car...
Reappraisal of Neuroendocrine Tumor Classification of the Prostate Gland: Translating Molecular Insights into Clinical Practice [0.03%]
前列腺神经内分泌肿瘤分类的再评估：将分子见解转化为临床实践
Anandi Lobo,Liang Cheng
Anandi Lobo
Neuroendocrine tumors (NETs) of the prostate gland represent a distinct entity within the spectrum of prostate cancer, characterized by neuroendocrine differentiation on morphology and unique clinical behavior. Despite their clinical signif...
Expression of DLL3 and SEZ6 in the Spectrum of Neuroendocrine Neoplasia [0.03%]
DLL3和SEZ6在神经内分泌肿瘤中的表达分布规律研究
Iqbal Ahmed,Amr Mohamed,Omid Savari et al.
Iqbal Ahmed et al.
Delta-like protein 3 (DLL3), a Notch ligand, has been identified in high-grade small- and large-cell lung carcinomas and prostate neuroendocrine carcinomas (NECs). SEZ6 (Seizure-related 6 homolog), a membrane-associated protein, has also be...
Correction: Impact of Tissue Thickness on Computational Quantification of Features in Whole Slide Images for Diagnostic Pathology [0.03%]
关于组织厚度对诊断病理学中 whole slide 图像特征计算量化影响的更正通知
Manav Shah,António Polónia,Mónica Curado et al.
Manav Shah et al.
Published Erratum
Endocrine pathology. 2025 Jul 19;36(1):26. DOI:10.1007/s12022-025-09872-1 2025
Roadmap to Challenges in Limited Cellularity Specimens from Pancreatic Neuroendocrine Neoplasms: Diagnostic Tools for the Most Appropriate Management of Limited Material [0.03%]
有限细胞量神经内分泌肿瘤胰腺标本的挑战及应对策略：最适当管理有限材料的诊断工具路线图
Stefano La Rosa,Roberta Maragliano,Deborah Marchiori
Stefano La Rosa
Fine needle aspiration (FNA) and fine needle biopsy (FNB) procedures are increasingly employed in the diagnostic work-up of pancreatic masses. These procedures represent a challenge for pathologists who have to adapt to handling specimens o...
Prognostic Features in Surgically Resected Well-Differentiated Pancreatic Neuroendocrine Tumors: an Analysis of 904 Patients with 7882 Person-Years of Follow-Up [0.03%]
手术切除的904例分化良好胰腺神经内分泌肿瘤患者的预后特征及7882人年的随访分析
Ashley L Kiemen,Eric D Young,Amanda L Blackford et al.
Ashley L Kiemen et al.
The clinical behavior of well-differentiated pancreatic neuroendocrine tumors (PanNETs) is difficult to predict. In order to define, more accurately, prognosticators for patients with a surgically resected PanNET, the pathologic features an...
Extended Hormone Profiling Identifies a Wider Network of Duodenal Neuroendocrine Tumor Subtypes [0.03%]
扩展激素谱分析确定了更广泛的十二指肠神经内分泌肿瘤亚型网络
Luvy Delfin,Shereen Ezzat,Sylvia L Asa
Luvy Delfin
We studied transcription factors and hormones expressed by duodenal neuroendocrine cells in a consecutively diagnosed series of 53 patients with well-differentiated duodenal NETs. There were 30 men; the mean age was 65 years (33 to 81). The...