The Proteome of Bilateral Macronodular Adrenocortical Disease (BMAD) Shows Different Profiles Correlating with the Genetic Causes and Reveals Specific Dysregulation of RNA Polymerase II and Cholesterol Biosynthesis Enzymes [0.03%]
双侧大结节性肾上腺皮质疾病（BMAD）的蛋白质组显示与遗传原因相关的不同谱型，并揭示了RNA聚合酶II和胆固醇生物合成酶的特定失调现象
Florian Violon,Anne Jouinot,Bruno Ragazzon et al.
Florian Violon et al.
New Insights from the Expression of the Mismatch Repair System in Pituitary Neuroendocrine Tumors [0.03%]
垂体神经内分泌肿瘤错配修复系统的表达新见解
Francesca Carbonara,Francesca Gianno,Tiziana Feola et al.
Francesca Carbonara et al.
Although defects in the mismatch repair (MMR) system have been occasionally reported in aggressive/metastatic pituitary neuroendocrine tumors (PitNETs), the potential role of MMR dysregulation in pituitary tumorigenesis is largely unknown. ...
Adult Pancreatoblastoma: A Challenge in the Differential Diagnosis of Pancreatic Neuroendocrine Neoplasms [0.03%]
成人胰腺blastoma的诊断挑战——与胰腺神经内分泌肿瘤鉴别的困难
Vincenzo Guastafierro,Dimitrios P Bouklas,Saverio Pancetti et al.
Vincenzo Guastafierro et al.
Quantitative Assessment of Focus Quality in Whole-Slide Imaging of Thyroid Liquid-Based Cytology Using Laplacian Variance [0.03%]
基于拉普拉斯方差的甲状腺液基细胞学全片扫描图像聚焦质量量化评估方法研究
Chan Kwon Jung,Chankyung Kim,Sora Jeon et al.
Chan Kwon Jung et al.
Reliable focus is essential for digital cytopathology, yet three-dimensional cell clusters in liquid-based cytology (LBC) slides pose persistent challenges for single-plane whole-slide imaging. We sought to quantitatively compare focus perf...
Multi-center Assessment of DLL3 Expression by Immunohistochemistry in Medullary Thyroid Carcinoma [0.03%]
多中心评价免疫组化检测甲状腺髓样癌DLL3表达
Ignacio Ruz-Caracuel,Alejandra Rosell,Lucie Geryková et al.
Ignacio Ruz-Caracuel et al.
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy accounting for 1-2% of thyroid carcinomas. As a neuroendocrine neoplasm, it shares molecular features with other aggressive neuroendocrine carcinomas, including alteratio...
Multicenter Study
Endocrine pathology. 2025 Dec 5;36(1):49. DOI:10.1007/s12022-025-09894-9 2025
Eleni Armeni,Tu-Vinh Luong,Ashley Grossman
Eleni Armeni
Endocrine and neuroendocrine malignancies, including epithelial neuroendocrine neoplasms (NENs), phaeochromocytoma/paraganglioma (PPGL), adrenocortical carcinoma (ACC) and thyroid cancers, represent a heterogeneous group of tumours often ch...
Correction to: Molecular Subtypes of Pancreatic Neuroendocrine Tumors Mutated in MEN1/DAXX/ATRX Explain Biological Variability [0.03%]
Correction to：MEN1/DAXX/ATRX基因突变的胰腺神经内分泌肿瘤分子亚型解释了生物变异性
Simona Avanthay,Annunziata Di Domenico,Philipp Kirchner et al.
Simona Avanthay et al.
Published Erratum
Endocrine pathology. 2025 Nov 26;36(1):47. DOI:10.1007/s12022-025-09892-x 2025
Follicular Thyroid Carcinoma Relapse Cases - Revisited by X-ray 3D Virtual Histology [0.03%]
滤泡型甲状腺癌复发病例的X射线三维虚拟组织学再评估
Kiarash Tajbakhsh,Olga Stanowska,Jonas Bossart et al.
Kiarash Tajbakhsh et al.
The diagnosis and prognosis of follicular thyroid neoplasms are based on the identification of capsular and vascular invasion. Although conventional histology allows accurate classification in most cases, its inherent limitations in tissue ...
Molecular Subtypes of Pancreatic Neuroendocrine Tumors Mutated in MEN1/DAXX/ATRX Explain Biological Variability [0.03%]
MEN1/DAXX/ATRX基因突变的胰腺神经内分泌肿瘤分子亚型解释了生物学差异
Simona Avanthay,Annunziata Di Domenico,Philipp Kirchner et al.
Simona Avanthay et al.
About 40% of non-functioning (NF) Pancreatic Neuroendocrine Tumors (PanNETs) harbour mutations in MEN1, often co-occurring with DAXX/ATRX. While the ADM group (MEN1 and DAXX/ATRX co-mutated) exhibits homogeneous genetic and epigenetic featu...
Phenotypic Landscape of Pulmonary Neuroendocrine Tumors: Subtyped by OTP/ASCL1 Expression Correlated with Histology, Hormones and Outcome [0.03%]
肺神经内分泌肿瘤的表型谱系：由OTP / ASCL1表达分型并结合组织学，激素和预后进行相关性分析
Ayako Ura,Katja Evert,Matthias Evert et al.
Ayako Ura et al.
Recent studies have shown that pulmonary neuroendocrine tumor (NET) subgroups, defined by the transcription factors OTP and ASCL1, correlate with age, sex, and tumor location. Their relationships with histology and hormone production, howev...