Impact of Co-Mutations and Genetic Variations on Malignancy Risk in RAS-Positive Indeterminate Thyroid Nodules: an Institutional Experience [0.03%]
RAS阳性甲状腺不确定结节恶性风险的共突变及遗传变异影响:单中心经验
Lawrence Q Wong,Zubair W Baloch
Lawrence Q Wong
Mutations in RAS proto-oncogenes (NRAS, HRAS, KRAS) are common in thyroid nodules, though their prognostic significance remains unclear. This retrospective study analyzed 354 thyroid nodules from 346 patients (2018-2023) to investigate the ...
Validation of the Reticulin Algorithm for Adrenocortical Neoplasms: Assessing Diagnostic Accuracy Across All Age Groups and Histological Subtypes [0.03%]
肾上腺皮质肿瘤reteculin算法验证:所有年龄段和组织学亚型中的诊断准确性评估
Hemlata Jangir,Sanjay Sriram,Sonali Dixit et al.
Hemlata Jangir et al.
Ampullary Mixed Adenoma and Well-Differentiated Neuroendocrine Tumor (MANET) with Aberrant Beta-Catenin Expression in a Patient with Neurofibromatosis Type 1 [0.03%]
1型神经纤维瘤病患者异位β-连环素表达的 ampullary 混合腺瘤和分化良好的神经内分泌肿瘤(MANET)病例报告
Dimitrios P Bouklas,Vincenzo Guastafierro,Silvia Carrara et al.
Dimitrios P Bouklas et al.
Histopathological and Molecular Characteristics of Pediatric Adrenocortical Tumors: where Do we Stand? [0.03%]
儿科肾上腺皮质肿瘤的病理和分子特征:我们目前处于什么位置?
Christianne C Swart,Ronald R de Krijger
Christianne C Swart
Pediatric adrenal cortical carcinoma (ACC) is a rare heterogeneous cancer type that is incompletely understood and differs from its adult counterpart in clinical presentation, histopathological characteristics, genomic landscape, and progno...
From Tissue Architecture To Genetic Signature: Artificial intelligence-based Analysis of Reticulin Framework and Clinical Variables Predicts Molecular Cluster in Paragangliomas [0.03%]
从组织结构到遗传标志:基于人工智能的网状素框架和临床变量分析预测副神经节瘤分子亚型
Eleonora Duregon,Mirko Parasiliti-Caprino,Giulia Orlando et al.
Eleonora Duregon et al.
Paragangliomas (PGLs), encompassing pheochromocytomas and extra-adrenal paragangliomas, are genetically heterogeneous non-epithelial neuroendocrine neoplasms that segregate into molecular clusters with distinct biological and clinical behav...
Immunohistochemical and Genetic Evidence of Lynch Syndrome-Related Well-Differentiated Pancreatic Neuroendocrine Tumor in Association with Peliosis of the Non-Tumorous Islets and Ductulo-Insular Complexes: An Expansion of Endocrine Manifestations of Lynch Syndrome [0.03%]
与非肿瘤胰岛和导管-岛样复合体血管畸形相关联的林奇综合征源发性高级别胰腺神经内分泌瘤的免疫组化及遗传学证据:林奇综合征的内分泌表现范围扩大
Ozgur Mete,Raymond Jang,Steven Gallinger
Ozgur Mete
Whole-Exome Profiling of Epstein-Barr Virus-Positive Neuroendocrine Carcinoma of the Nasopharynx [0.03%]
鼻咽部EB病毒阳性神经内分泌癌的外显子组特征分析
Xin-Chun Chen,Jian-Chang Fu,Ao Zhang et al.
Xin-Chun Chen et al.
Epstein-Barr virus (EBV)-positive neuroendocrine carcinoma (NEC) of the nasopharynx is a rare malignancy with poor prognosis and lacks squamous markers, rendering it biologically distinct from nasopharyngeal carcinoma (NPC) of squamous epit...
Composite Gangliocytoma/Neuroma and Neuroendocrine Tumor (CoGNET) of the Duodenum: An Image in Endocrine Pathology Exploring Patterns of Biomarker Expression in Tumor Elements [0.03%]
复合神经节细胞瘤/神经纤维瘤和神经内分泌肿瘤(CoGNET)的十二指肠:内分泌病理图像探索肿瘤成分中的生物标志物表达模式
Ozgur Mete,Assem Alrumeh,Sara Hafezi Bakhtiari
Ozgur Mete
Non-Invasive Follicular Cell-Derived Thyroid Neoplasm Composed Entirely of Spindle Cells Harboring NRAS p.Q61R Mutation and Variable Atypia [0.03%]
由NRAS p.Q61R突变和不同程度异型性组成的全部由梭形细胞构成的非侵袭性滤泡细胞来源甲状腺新生物
Toru Odate,So Shimekake,Tatsuya Horiuchi et al.
Toru Odate et al.