Impact of Molecular Testing on Surgical Decision-Making in Indeterminate Thyroid Nodules: A Global Meta-Analysis Across Test Generations [0.03%]
分子检测对未确定甲状腺结节手术决策影响的全球性 meta 分析：各代检测技术的分析
Truong Phan-Xuan Nguyen,Andrey Bychkov,Chan Kwon Jung et al.
Truong Phan-Xuan Nguyen et al.
Thyroid nodules with indeterminate cytology represent a clinical challenge owing to uncertain malignancy risk, often leading to diagnostic surgery. Molecular testing has emerged as a promising adjunct to improve risk stratification and guid...
Molecular Profiling of Digestive Grade 3 Neuroendocrine Tumors Reveals a Shared Molecular Framework with Lower-Grade Tumors, Marked Heterogeneity, and Therapeutic Opportunities [0.03%]
消化道三级神经内分泌肿瘤分子分型揭示与低级别肿瘤共有的分子特征、显著的异质性及治疗机会
Amedeo Sciarra,Laura Libera,Annarita Destro et al.
Amedeo Sciarra et al.
Well-differentiated neuroendocrine tumors, grade 3 (NETs G3) of the digestive system are high-grade neuroendocrine neoplasms characterized by well-differentiated neuroendocrine morphology and high proliferative activity. Their molecular ide...
Lineage Classification of Pituitary Neuroendocrine Tumors From Whole-Slide Images Using Attention-Guided Graph Representation Learning [0.03%]
基于注意力引导图表示学习的垂体神经内分泌肿瘤全片图像系谱分类
Jie Hao,Chen Wang,Jiao Li et al.
Jie Hao et al.
Pituitary neuroendocrine tumors (PitNETs) are common sellar neoplasms and represent a major component of routine pituitary pathology. In the 2022 World Health Organization (WHO) Classification, transcription factor-defined lineage assignmen...
Clinicopathologic and Molecular Features of Poorly Differentiated Thyroid Carcinomas in Adults ≤ 45 Years of Age [0.03%]
≤45岁成人分化差型甲状腺癌的临床病理和分子特征分析
Maria Cristina Riascos,Ellen Marqusee,Sara Ahmadi et al.
Maria Cristina Riascos et al.
The clinical behavior and molecular underpinnings of rare cases of poorly differentiated thyroid carcinoma (PDTC) diagnosed in young adults are not established. We evaluated 13 cases of PDTC in adult patients ≤ 45 years of age. The median ...
Thyroblastoma Dominated by a Primitive Small Round Cell Component: A Diagnostic Pitfall [0.03%]
以原始小圆细胞为主的甲状腺母细胞瘤：一种容易误诊的病例
Atsuko Kasajima,Marco M E Vogel,Günter Klöppel et al.
Atsuko Kasajima et al.
Thyroid Tumors of Uncertain Malignant Potential (UMP)- Clinicopathologic and Molecular Characterization of 324 Cases [0.03%]
324例甲状腺肿瘤不确定恶性潜能（UMP）的临床病理及分子特征分析
Bayan A Alzumaili,William C Faquin,Adam S Fisch et al.
Bayan A Alzumaili et al.
Well-Differentiated Neuroendocrine Tumors of Lung: A Case Series Supporting the IARC/WHO Common Classification of Neuroendocrine Tumor Nomenclature and Grading [0.03%]
肺神经内分泌肿瘤的诊断和分类：支持IARC / WHO神经内分泌肿瘤命名法和分级的病例系列分析
Eren Altun,Omid Savari,Mart Andrew Maravillas et al.
Eren Altun et al.
The aim of this study was to assess whether there is sufficient evidence to recommend a change in the classification of pulmonary tumors currently classified as “carcinoid” tumors to instead apply a system similar to that used for well-di...
Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients [0.03%]
原发性醛固酮增多症患者醛固酮产生微结节中驱动突变频率增加及不同基因型模式的研究
Jung Soo Lim,Chun-Yi Wu,Zhaoping Qin et al.
Jung Soo Lim et al.
Primary aldosteronism (PA) is the leading cause of endocrine hypertension. With the development of highly specific human aldosterone synthase (CYP11B2) antibodies for immunohistochemistry (IHC), the presence of microscopic subcapsular foci ...
Clinical and Pathological Features of EC-cell Familial Small Intestine Neuroendocrine Tumors: A Nationwide Cohort From the French GTE-RENATEN Network [0.03%]
家族性肠嗜铬细胞小肠神经内分泌肿瘤的临床和病理特征——来自法国GTE-RENATEN网络全国队列报告
Thomas Hunaut,Laura Gérard,Agathe Hercent et al.
Thomas Hunaut et al.
In-depth Genetic and Molecular Characterization of Unilateral Coexisting Adrenal Cortical Adenoma and Carcinoma in the Context of MEN1 Syndrome [0.03%]
一例MEN1综合征合并单侧肾上腺皮质腺瘤和皮质癌的遗传及分子特征分析
Francesca Cioppi,Tommaso Orioli,Giulia Cantini et al.
Francesca Cioppi et al.
Adrenal lesions often occur in patients with multiple endocrine neoplasia type 1 (MEN1), mostly adrenal cortical adenomas (ACAs), although the frequency of adrenal cortical carcinomas (ACCs) is higher than in the general population. The coe...