Immunoexpression of androgen receptor in the nontumorous pituitary and in adenomas [0.03%]
正常垂体和腺瘤中的雄激素受体免疫表达
Bernd W Scheithauer,Kalman Kovacs,Suzan Zorludemir et al.
Bernd W Scheithauer et al.
Little information is available regarding androgen receptor immunoexpression (AR) in the normal and neoplastic human pituitary. Available experimental data links it to primarily gonadotroph cells. We undertook an immunohistochemical study o...
ACTH and alpha-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells [0.03%]
促肾上腺皮质激素和α亚单位在罕见的人类垂体皮质醇细胞腺瘤中共表达，这些腺瘤被认为起源于促肾上腺皮质激素committed早期垂体祖细胞
Masanori Suzuki,Noboru Egashira,Hanako Kajiya et al.
Masanori Suzuki et al.
The functional differentiation of pituitary cells and adenomas follows the combination of transcription factors and co-factors in three cell lineages [growth hormone-prolactin-thyroid-stimulating hormone lineage, adrenocorticotrophic hormon...
Does fine-needle aspiration cytology optimize the surgical management of thyroid disorders in endemic goiter region? [0.03%]
细针吸抽涂片细胞学检查对地方性甲状腺肿患者外科治疗的优化作用
Iyad Hassan,Thomas Osei-Agymang,E Domínguez Fernández et al.
Iyad Hassan et al.
Aim: The aim of this study was to determine the diagnostic value of fine-needle aspiration cytology (FNAC) before thyroidectomy in an endemic goiter region. ...
Vânia Nosé,Marco Volante,Mauro Papotti
Vânia Nosé
Hyalinizing trabecular tumor (HTT) is a rare thyroid tumor of follicular cell origin with a trabecular pattern of growth and marked intratrabecular hyalinization. This tumor is known to share morphological and architectural similarities wit...
Neurofilaments in Thyrotrophs of Hypothyroid Rats: An Immunohistochemical Study [0.03%]
亚甲状腺功能亢进大鼠垂体甲状腺素生成细胞中神经丝蛋白的免疫组化研究
Eva Salinas,J. Luis Quintanar
Eva Salinas
We examined by immunohistochemistry the expression of 200-kDa (NF-H) neurofilaments in pituitary thyrotrophs of rats, made hypothyroid by propylthiouracil (PTU) administration. Rats were sacrificed at 3, 7, 14, and 28 d of PTU administratio...
Correlation Between Clinical and Histological Analyses in Retroocular Connective Tissues and Extraocular Muscles from Patients with Graves' Ophthalmopathy [0.03%]
格雷夫斯眼病患者眼外肌和眼眶结缔组织临床分析与病理分析的相关性研究
Kimble Matos,Vania Nosé V,Paulo Gois Manso et al.
Kimble Matos et al.
Twenty-two patients with Graves' ophthalmopathy underwent biopsy, and two patients had both eyes biopsied. The samples for the control group (n = 4) were obtained during routine non-thyroid-related corrective strabismus surgery. Ophthalmolo...
Insulin and Glucagon mRNA Expression and Prohormone Convertase Immunoreactivity in Normal and Neoplastic Pancreatic Endocrine Tissue [0.03%]
正常和肿瘤胰腺内分泌组织中胰岛素和胰高血糖素的mRNA表达及前激素转化酶的免疫反应性
Mark Rodacker,Long Jin,Shuga Zhang et al.
Mark Rodacker et al.
Prohormone convertase (PC) 1/3 and PC2 are neuroendocrine-specific enzymes that convert prohormones to active hormones. To learn more about the role of these PCs in normal and neoplastic islet cells, we analyzed a series of pancreatic endoc...
Silver-Staining Nucleolar Organizer Region Quantification in Pituitary Adenomas [0.03%]
垂体腺瘤中的银染核仁组织者区域定量分析
Dorota Sowiska-Klencka,Mariusz Klencki,Marek Dedecjus et al.
Dorota Sowiska-Klencka et al.
Nucleolar organizer regions (NORs) are segments of DNA, encoding for ribosomal RNA. They are associated with argyrophilic proteins and, thus, they can be localized through silver staining. A correlation has been shown between the number, th...
Immunocytochemical Localization of Prohormone Convertase 1/3 and 2 in Thyroid C-Cells and Medullary Thyroid Carcinomas [0.03%]
甲状腺C细胞和甲状腺髓样癌中前激素转化酶1/3和2的免疫细胞化学定位
Tatsuo Tomita
Tatsuo Tomita
Prohormone convertases (PCs) are the key enzymes in the regulated pathways for the post-translational processing of peptide hormones and are involved in converting larger prohormones to smaller, biologically active hormones. Immunolocalizat...
Combined Riedel's Disease and Fibrosing Hashimoto's Thyroiditis: A Report of Three Cases with Two Showing Coexisting Papillary Carcinoma [0.03%]
瑞德尔病合并桥本甲状腺炎的临床病理报告2例伴乳头状癌病理变化
Zubair W. Baloch,Michael D. Feldman,Virginia A. LiVolsi
Zubair W. Baloch
Extensive sclerosis of the thyroid gland can be seen in both benign and malignant conditions. The benign sclerosing lesions of the thyroid include Riedel's disease and fibrosing Hashimoto's thyroiditis. Although these conditions usually occ...