Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres) [0.03%]
产生胰高糖素的神经内分泌肿瘤（胰高糖素瘤）富含ARX和PDX1共表达、DAXX/ATRX突变和ALT（端粒异常延长）的侵袭性肿瘤
Paola Mattiolo,Michele Bevere,Andrea Mafficini et al.
Paola Mattiolo et al.
Glucagonomas are functioning pancreatic neuroendocrine tumors (PanNETs) responsible for glucagonoma syndrome. This study aims to shed light on the clinicopathological and molecular features of these neoplasms. Six patients with glucagonomas...
Novel Drop-off PCR Assay for USP8 Hotspot Variant Detection in Corticotroph Tumors [0.03%]
一种新型PCR测定方法用于库欣病促肾上腺皮质激素分泌肿瘤中USP8热点突变的检测
Renan Lyra Miranda,Alexandro Guterres,Carlos Henrique de Azeredo Lima et al.
Renan Lyra Miranda et al.
Somatic Molecular Heterogeneity in Bilateral Macronodular Adrenocortical Disease (BMAD) Differs Among the Pathological Subgroups [0.03%]
双侧肾上腺大结节病(BMAD)病理亚组的体细胞分子异质性不同
Florian Violon,Lucas Bouys,Patricia Vaduva et al.
Florian Violon et al.
Bilateral macronodular adrenocortical disease (BMAD) is an uncommon cause of Cushing's syndrome leading to bilateral macronodules. Isolated BMAD has been classified into three molecular groups: patients with ARMC5 alteration, KDM1A alterati...
Isolated Tumor Cells Node Micro-metastasis in Early-Stage Small Intestinal Neuroendocrine Tumor [0.03%]
早期小肠神经内分泌肿瘤孤立癌细胞及淋巴结微转移的研究
Giulia Scaglione,Pietro Fransvea,Enza Genco et al.
Giulia Scaglione et al.
PD-L1 and B7-H3 are Effective Prognostic Factors and Potential Therapeutic Targets for High-Risk Thyroid Cancer [0.03%]
PD-L1和B7-H3是高风险甲状腺癌的有效预后因素和潜在治疗靶点
Xinyi Zhu,Chunfang Hu,Zhe Zhang et al.
Xinyi Zhu et al.
The prognosis of thyroid cancer in patients varies significantly based on different pathological types or distinct clinical situations. Investigating the expression of immune checkpoint molecules PD-L1 and B7-H3 in high-risk thyroid cancer ...
Detection of RAS p.Q61R by Immunohistochemistry in Practice: A Clinicopathologic Study of 217 Thyroid Nodules with Molecular Correlates [0.03%]
基于分子的回顾性研究：免疫组化在检测甲状腺结节中RAS p.Q61R突变的临床病理价值分析（附217例分析）
Bayan A Alzumaili,Adam S Fisch,William C Faquin et al.
Bayan A Alzumaili et al.
RAS p.Q61R is the most prevalent hot-spot mutation in RAS and RAS-like mutated thyroid nodules. A few studies evaluated RAS p.Q61R by immunohistochemistry (RASQ61R-IHC). We performed a retrospective study of an institutional cohort of 150 p...
Granulation Patterns of Functional Corticotroph Tumors Correlate with Tumor Size, Proliferative Activity, T2 Intensity-to-White Matter Ratio, and Postsurgical Early Biochemical Remission [0.03%]
功能皮质促肾上腺皮质激素肿瘤的颗粒化模式与肿瘤大小、增殖活性、T2信号白质比值及术后早期生化缓解相关性研究
Elif Tutku Durmuş,Mehmet Kefeli,Ozgur Mete et al.
Elif Tutku Durmuş et al.
Unlike somatotroph tumors, the data on correlates of tumor granulation patterns in functional TPIT lineage pituitary neuroendocrine tumors (corticotroph tumors) have been less uniformly documented in most clinical series. This study evaluat...
Primary Secretory Carcinoma of the Thyroid Gland with ETV6::NTRK3 Gene Fusion [0.03%]
具有ETV6::NTRK3基因融合的原发性甲状腺分泌癌
Rumeal D Whaley,Lori A Erickson
Rumeal D Whaley
Rumeal D Whaley,Andrew L Folpe,Lori A Erickson
Rumeal D Whaley
Transcriptomic Differences in Medullary Thyroid Carcinoma According to Grade [0.03%]
根据分级髓样甲状腺癌的转录组差异
Ignacio Ruz-Caracuel,Tamara Caniego-Casas,Teresa Alonso-Gordoa et al.
Ignacio Ruz-Caracuel et al.
Medullary thyroid carcinoma (MTC) is a rare cancer derived from neuroendocrine C-cells of the thyroid. In contrast to other neuroendocrine tumors, a histological grading system was lacking until recently. A novel two-tier grading system bas...