Type 2 deiodinase-dependent surge in thyroid hormone controls muscle stem cell quiescence and self-renewal [0.03%]
Ⅱ型脱碘酶依赖性的甲状腺激素脉冲控制肌肉干细胞的静息和自我更新
Maria Angela De Stefano,Raffaele Ambrosio,Cristina Luongo et al.
Maria Angela De Stefano et al.
Stem cells are critical for the homeostasis of adult tissues. Thyroid hormone (TH), whose intracellular concentration is increased by type 2 deiodinase (D2), is involved in many functions, but its role in quiescence is unknown. Here we show...
A therapeutic role for a regulatory glucose transporter1 (GLUT1)-associated lncRNA in GLUT1-deficient mice [0.03%]
调控型葡萄糖转运蛋白1(GLUT1)相关长链非编码RNA在GLUT1缺陷小鼠中的治疗作用
Maoxue Tang,Sasa Teng,Yueqing Peng et al.
Maoxue Tang et al.
The mammalian brain relies primarily on glucose for its energy needs. Delivery of this nutrient to the brain is mediated by the glucose transporter-1 (GLUT1) protein. Low GLUT1 thwarts glucose entry into the brain, causing an energy crisis ...
Estrogen deficiency and risk of hearing loss in pediatric Turner syndrome [0.03%]
雌激素缺乏与儿童特纳综合征听力损失的风险关系
Yan Huang,Liyang Liang,Yanfang Ye et al.
Yan Huang et al.
Background: Estrogen deficiency and progressive hearing loss (HL) are significant concerns in individuals with Turner syndrome (TS). However, whether childhood estrogen deficiency increases HL risk and whether estrogen re...
Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs [0.03%]
结肠Engyodontium真菌触发中性粒细胞的抗菌活性以抑制Lactobacillus johnsonii来源的谷氨酸维持的调节性T细胞
Xinying Wang,Haiyang Sun,Ying Tan et al.
Xinying Wang et al.
Isolating commensal fungi from mouse intestines has been challenging, limiting our understanding of their role in intestinal immune homeostasis and diseases. Using an Fc fusion protein of the C-type lectin Dectin-2, we successfully purified...
Corrigendum to Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance [0.03%]
p120-catensin胞浆区通过Rock1介导的悬浮耐受调节侵袭性小叶癌生长（校正）
Ron Cj Schackmann,Miranda van Amersfoort,Judith Hi Haarhuis et al.
Ron Cj Schackmann et al.
Published Erratum
The Journal of clinical investigation. 2026 Mar 2;136(5):e204857. DOI:10.1172/JCI204857 2026
Raghavendra G Mirmira
Raghavendra G Mirmira
How the host becomes the target: exploiting an intracellular transport pathway to treat coronaviruses [0.03%]
如何使宿主变成目标：利用细胞内运输途径治疗冠状病毒
Pablo Penaloza-MacMaster
Pablo Penaloza-MacMaster
Chuanyu Guo,Akrit Sodhi
Chuanyu Guo
Diabetic retinopathy (DR), the most common microvascular complication in patients with diabetes mellitus (DM), is a leading cause of vision loss worldwide. Sustained hyperglycemia plays a central role in promoting DR. However, tight glycemi...
Ectopic B lymphocyte follicles exacerbate ischemic brain damage via MIF-CD74/CXCR4 and interferon signaling [0.03%]
异位B淋巴细胞滤泡通过MIF-CD74/CXCR4和干扰素信号加重缺血性脑损伤
Sheng Yang,Hang Zhang,Lu-Lu Xu et al.
Sheng Yang et al.
Neuroinflammation, encompassing both innate and adaptive immune responses, plays a crucial role in ischemic stroke. Although B lymphocytes are central to adaptive immunity, their contributions to ischemic stroke remain poorly understood. He...
Activin A secretion by muscle-repairing macrophages induces heterotopic ossification in mice [0.03%]
小胶质细胞分泌的活化素A诱导异位骨化
Wenqiang Yin,Kazuo Okamoto,Asuka Terashima et al.
Wenqiang Yin et al.
The immune system is not only essential for host defense, but it is also involved in tissue maintenance and disease pathogenesis. Macrophages play a key role in tissue repair, fibrosis, and tumorigenesis, but the mechanisms underlying their...