Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities [0.03%]
Nathaniel W Rolfe,Nicholas B Dadario,Liang Lei et al.
Nathaniel W Rolfe et al.
Dexamethasone is widely used to control cerebral edema and inflammation in glioblastoma, but its benefits are limited by systemic toxicities and adverse prognostic associations. We evaluated local administration of dexamethasone via convect...
CD73 inhibition overcomes adaptive immune resistance to PARP inhibition in models of prostate cancer [0.03%]
CD73抑制可克服前列腺癌模型中PARP抑制的适应性免疫抵抗现象
Ping Xie,Renqiang Ma,Minghui Zhang et al.
Ping Xie et al.
Metastatic castration-resistant prostate cancer (mCRPC) remains a leading cause of cancer-related mortality in men. Although poly(ADP-ribose) polymerase (PARP) inhibitors are approved for mCRPC patients with homologous recombination repair ...
Polycomb scaffolding subunit EED supports the SCLC neuroendocrine identity and EGFR-mutant LUAD-to-SCLC transformation [0.03%]
多梳子单元EED支持小细胞肺癌的神经内分泌身份和LUAD至SCLC的转化（EGFR突变）
Yixiang Li,Yasmin N Laimon,Hyeonseo Cho et al.
Yixiang Li et al.
Lung cancer histological subtypes include lung adenocarcinoma (LUAD) and small-cell lung cancer (SCLC). Although usually distinct, rare combined LUAD/SCLC tumors occur, and LUAD can transform into SCLC as a mechanism of resistance to target...
Corrigendum to Single-cell DNA sequencing reveals a high incidence of chromosomal abnormalities in human blastocysts [0.03%]
单细胞DNA测序显示人类囊胚中染色体异常率较高[致编辑函]
Effrosyni A Chavli,Sjoerd J Klaasen,Diane Van Opstal et al.
Effrosyni A Chavli et al.
Published Erratum
The Journal of clinical investigation. 2026 Aug 17;136(16):e210864. DOI:10.1172/JCI210864 2026
Second corrigendum to Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease [0.03%]
鲁索利替尼通过恢复急性移植物抗宿主病中骨髓基质细胞功能来改善造血再生的第二更正
Yan Lin,Quan Gu,Shihong Lu et al.
Yan Lin et al.
Published Erratum
The Journal of clinical investigation. 2026 Aug 17;136(16):e210543. DOI:10.1172/JCI210543 2026
Corrigendum to SUMOylation promotes extracellular vesicle-mediated transmission of lncRNA ELNAT1 and lymph node metastasis in bladder cancer [0.03%]
SUMO化促进长链非编码RNA ELNAT1介导的膀胱癌淋巴结转移及胞外囊泡运输的校正说明
Changhao Chen,Hanhao Zheng,Yuming Luo et al.
Changhao Chen et al.
Published Erratum
The Journal of clinical investigation. 2026 Aug 17;136(16):e210810. DOI:10.1172/JCI210810 2026
Corrigendum to Helicobacter pylori-induced PPFIA4 orchestrates immune network-promoting gastritis and gastric bacterial colonization [0.03%]
幽门螺杆菌诱导的PPFIA4调控免疫网络促进胃炎和胃部细菌定植的勘误证伪通知
Pan Wang,Nan You,Yong-Sheng Teng et al.
Pan Wang et al.
Published Erratum
The Journal of clinical investigation. 2026 Aug 17;136(16):e210814. DOI:10.1172/JCI210814 2026
Radiotherapy and immunotherapy in cancer treatment: mechanisms of clinical synergy [0.03%]
放疗与癌症免疫治疗：临床协同机制
Lu Lu,Liufu Deng
Lu Lu
Synergizing radiotherapy (RT) with immune checkpoint inhibitors has emerged as a promising strategy for solid tumors. RT acts as a potent immunomodulator, capable of functioning as an in situ vaccine through the induction of immunogenic cel...
Serdar E Bulun
Serdar E Bulun
Retraction of The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy [0.03%]
CO/HO系统撤除逆转多柔比星诱导的心肌病中线粒体生物生成抑制的作用
Hagir B Suliman,Martha Sue Carraway,Abdelwahid S Ali et al.
Hagir B Suliman et al.