Jenna Fernandez,Pankaj Pradeep,Mrinal M Patnaik
Jenna Fernandez
Purpose of review: Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm that is characterized by sustained monocytic proliferation, bone marrow dysplasia, and progression to acute myeloi...
Chronic Myelomonocytic Leukemia Microenvironment in Disease Progression and Therapy: Focus on Stepwise Reconfiguring of Myeloid-Immune Cell Interactions Driving Immune Tolerance [0.03%]
慢性单核细胞白血病疾病进展和治疗中的微环境：逐步重塑髓系-免疫细胞互作导致免疫耐受的焦点问题研究
Ali Khalid A Alsugair,Abhishek Mangaonkar
Ali Khalid A Alsugair
Purpose of the review: To summarize evidence and provide an overview of the microenvironment and myeloid-immune cell interactions within the chronic myelomonocytic leukemia (CMML) microenvironment that drive mutation-agno...
Nico Gagelmann,Nihar Desai
Nico Gagelmann
Purpose of review: Chronic myelomonocytic leukemia (CMML) is a rare hematologic malignancy at the intersection of myelodysplastic (MDS) and myeloproliferative neoplasms, predominantly affecting older adults. Allogeneic he...
Highlights from MPN Asia 2025: Advances in Molecular Pathogenesis and Therapeutic Strategies in Myeloproliferative Neoplasms [0.03%]
MPN亚洲2025会议亮点：我的增生性肿瘤分子发病机制和治疗策略的进展
Prithviraj Bose,Zhijian Xiao,Hans C Hasselbalch et al.
Prithviraj Bose et al.
Purpose of review: This report summarizes key insights from the 8th Annual International Symposium on Myeloproliferative Neoplasms (MPN Asia 2025). The symposium brought together global experts to discuss advancements in ...
Dahniel Sastow,Arjun Syal,Douglas Tremblay
Dahniel Sastow
Purpose of review: Chronic myelomonocytic leukemia (CMML), a rare myelodysplastic/myeloproliferative neoplasm (MDS/MPN) overlap syndrome, poses diagnostic and therapeutic challenges due to its heterogeneity and rarity. Th...
Helen T Chifotides,Andrea Duminuco,Elena Torre et al.
Helen T Chifotides et al.
Purpose of review: In this review, we highlight conventional agents and novel emerging therapeutic strategies to treat anemia in MF. Recent findings: ...
Role of Population Based Studies in Advancing our Knowledge of Myelodysplastic Syndromes [0.03%]
基于人口的研究在增进对骨髓发育不良综合征的认识中的作用
Diego A Adrianzen-Herrera,Aneta Strumlowska
Diego A Adrianzen-Herrera
Purpose of the review: Myelodysplastic syndromes (MDS) are myeloid neoplasms characterized by high molecular and genomic heterogeneity. Accordingly, efforts in risk assessment and therapeutic intervention mostly target un...
Advances in Novel Systemic Therapies for the Management of Cutaneous T Cell Lymphoma (CTCL) [0.03%]
新型系统性疗法在皮肤T细胞淋巴瘤(CTCL)管理中的应用进展
Katherine B Case,Pamela B Allen
Katherine B Case
Purpose of review: Cutaneous T cell lymphomas (CTCLs) are comprised of a heterogenous group of non-Hodgkin lymphomas that can be difficult to treat and are often refractory to standard therapies. Mycosis fungoides (MF) an...
Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications [0.03%]
MPN中的突变型钙联蛋白：机制及治疗意义
Mifra Faiz,Merle Riedemann,Jonas S Jutzi et al.
Mifra Faiz et al.
Purpose of review: More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continue to emerge. Here, w...
Navigating the Economic Burden of Multiple Myeloma: Insights into Cost-effectiveness of CAR-T and Bispecific Antibody Therapies [0.03%]
多重骨髓瘤的经济负担及CAR-T和双特异性抗体治疗的成本效益分析
Praneeth Reddy Keesari,Diana Samuels,Charan Thej Reddy Vegivinti et al.
Praneeth Reddy Keesari et al.
Purpose of review: Multiple myeloma is a chronic malignancy and with evolving treatment options, understanding the economic burden and cost-effectiveness of therapies is crucial for clinicians and researchers. ...