Linking Air Pollution and Hematologic Malignancies: From Epidemiology to Molecular Mechanisms [0.03%]
从流行病学角度到分子机制：空气污染与血液系统恶性肿瘤的关系研究
Hamsa Murli,Sadia Alam,Evelyn Mesler et al.
Hamsa Murli et al.
Purpose of review: Outdoor air pollution (OAP) is a major global environmental health threat associated with respiratory disease and solid tumors, with growing evidence linking it to hematologic malignancies. This review ...
Antigen Pressure, Clonal Evolution, and Lineage Plasticity in B-Cell Acute Lymphoblastic Leukemia: Resistance Biology in the Immunotherapy Era [0.03%]
抗原压力、克隆进化和谱系可塑性在B细胞急性淋巴细胞白血病中的作用：免疫治疗时代的耐药生物学
Julio Alvarenga Thiebaud,Tamer Othman,Ibrahim Aldoss
Julio Alvarenga Thiebaud
Purpose of review: Targeted immunotherapies have transformed the treatment of relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL), yet their efficacy depends on sustained expression of lineage-associated s...
Beyond Survival: Measuring Treatment Tolerability with Patient-Reported Outcomes in the Lymphoma Immunotherapy Era [0.03%]
超越生存：在淋巴瘤免疫治疗时代利用患者报告结果评估治疗耐受性
Elisa Hofmeister,Ajay Major
Elisa Hofmeister
Purpose of review: Immunotherapeutic strategies for the treatment of lymphomas are rapidly expanding and can deliver durable remissions to patients with historically limited treatment options. Patient-reported outcomes (P...
Chronic Myelomonocytic Leukemia: History, Pathobiology, Diagnostic Controversies, and Evolving Classification [0.03%]
慢粒单核细胞白血病：历史、病理生物学、诊断争议及分类进展
Sanam Loghavi,Robert P Hasserjian
Sanam Loghavi
Purpose of review: Chronic myelomonocytic leukemia (CMML) is a clonal myelodysplastic/myeloproliferative neoplasm characterized by sustained monocytosis, recurrent gene mutations, and a risk of transformation to acute mye...
Breaching the Blood-Brain Barrier: Evolving Strategies for Central Nervous System Disease in Adult Acute Lymphoblastic Leukemia [0.03%]
成人急性淋巴细胞白血病中枢神经系统疾病的演变策略：突破血脑屏障
Liesl S Eibschutz,Samuel Crow,Caroline Tatum et al.
Liesl S Eibschutz et al.
Purpose of review: Central nervous system (CNS) involvement in adult acute lymphoblastic leukemia (ALL) remains a critical determinant of treatment failure and long-term survival. This review provides a comprehensive, evi...
Luca Arcuri,Emma M Groarke,Sharon A Savage et al.
Luca Arcuri et al.
Published Erratum
Current hematologic malignancy reports. 2026 Jul 10;21(1):13. DOI:10.1007/s11899-026-00783-4 2026
BRAF Alterations in Chronic Lymphocytic Leukemia: Genomic Landscape, Co-Mutation Patterns, and Clinical Relevance [0.03%]
慢性淋巴细胞白血病中BRAF突变的基因组改变、共突变模式及其临床意义研究
Abdulrahman Al-Abdulmalek,Eric Landry,Mohammed Abdulgayoom et al.
Abdulrahman Al-Abdulmalek et al.
Purpose of review: BRAF alterations are uncommon in chronic lymphocytic leukemia (CLL), yet increasing use of broad genomic profiling has identified them as a recurrent component of MAPK-pathway dysregulation. This revise...
Targeting the BCR::ABL1 Kinase: Advances Beyond Imatinib in Chronic Myeloid Leukemia [0.03%]
BCR-ABL1激酶靶向治疗：慢性粒细胞白血病伊马替尼治疗之外的新进展
Zuhal Naderi,Teresa Sadras,Susan Branford et al.
Zuhal Naderi et al.
Aldo A Acosta-Medina,Abhishek A Mangaonkar
Aldo A Acosta-Medina
Luca Arcuri,Emma M Groarke,Sharon A Savage et al.
Luca Arcuri et al.
Purpose of Review: In inherited bone marrow failure syndromes (IBMFS), clonal hematopoiesis (CH) has been increasingly recognized as a molecular fingerprint of the underlying pathophysiology. A specific clonal profile has...