Nico Gagelmann,Nihar Desai
Nico Gagelmann
Purpose of review: Chronic myelomonocytic leukemia (CMML) is a rare hematologic malignancy at the intersection of myelodysplastic (MDS) and myeloproliferative neoplasms, predominantly affecting older adults. Allogeneic he...
Highlights from MPN Asia 2025: Advances in Molecular Pathogenesis and Therapeutic Strategies in Myeloproliferative Neoplasms [0.03%]
MPN亚洲2025会议亮点：我的增生性肿瘤分子发病机制和治疗策略的进展
Prithviraj Bose,Zhijian Xiao,Hans C Hasselbalch et al.
Prithviraj Bose et al.
Purpose of review: This report summarizes key insights from the 8th Annual International Symposium on Myeloproliferative Neoplasms (MPN Asia 2025). The symposium brought together global experts to discuss advancements in ...
Dahniel Sastow,Arjun Syal,Douglas Tremblay
Dahniel Sastow
Purpose of review: Chronic myelomonocytic leukemia (CMML), a rare myelodysplastic/myeloproliferative neoplasm (MDS/MPN) overlap syndrome, poses diagnostic and therapeutic challenges due to its heterogeneity and rarity. Th...
Helen T Chifotides,Andrea Duminuco,Elena Torre et al.
Helen T Chifotides et al.
Purpose of review: In this review, we highlight conventional agents and novel emerging therapeutic strategies to treat anemia in MF. Recent findings: ...
Role of Population Based Studies in Advancing our Knowledge of Myelodysplastic Syndromes [0.03%]
基于人口的研究在增进对骨髓发育不良综合征的认识中的作用
Diego A Adrianzen-Herrera,Aneta Strumlowska
Diego A Adrianzen-Herrera
Purpose of the review: Myelodysplastic syndromes (MDS) are myeloid neoplasms characterized by high molecular and genomic heterogeneity. Accordingly, efforts in risk assessment and therapeutic intervention mostly target un...
Advances in Novel Systemic Therapies for the Management of Cutaneous T Cell Lymphoma (CTCL) [0.03%]
新型系统性疗法在皮肤T细胞淋巴瘤(CTCL)管理中的应用进展
Katherine B Case,Pamela B Allen
Katherine B Case
Purpose of review: Cutaneous T cell lymphomas (CTCLs) are comprised of a heterogenous group of non-Hodgkin lymphomas that can be difficult to treat and are often refractory to standard therapies. Mycosis fungoides (MF) an...
Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications [0.03%]
MPN中的突变型钙联蛋白：机制及治疗意义
Mifra Faiz,Merle Riedemann,Jonas S Jutzi et al.
Mifra Faiz et al.
Purpose of review: More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continue to emerge. Here, w...
Navigating the Economic Burden of Multiple Myeloma: Insights into Cost-effectiveness of CAR-T and Bispecific Antibody Therapies [0.03%]
多重骨髓瘤的经济负担及CAR-T和双特异性抗体治疗的成本效益分析
Praneeth Reddy Keesari,Diana Samuels,Charan Thej Reddy Vegivinti et al.
Praneeth Reddy Keesari et al.
Purpose of review: Multiple myeloma is a chronic malignancy and with evolving treatment options, understanding the economic burden and cost-effectiveness of therapies is crucial for clinicians and researchers. ...
Shayna Sarosiek,Christopher T Doughty,Jorge J Castillo
Shayna Sarosiek
Purpose of review: Peripheral neuropathy (PN) is more commonly seen in individuals with monoclonal gammopathies, especially in patients with an IgM monoclonal gammopathy or Waldenström macroglobulinemia. ...
Disparities in Clinical Trial Enrollment- Focus on CAR-T and Bispecific Antibody Therapies [0.03%]
CAR-T和双特异性抗体疗法临床试验登记的差异性分析
Nadia Islam,Laura Budvytyte,Nandita Khera et al.
Nadia Islam et al.
Purpose of review: Recent studies show that unresolved disparities hinder enrollment to clinical trials, equitable distribution of treatments, and impact the generalizability of trials, compromising health outcomes across...