The Evolving Landscape of Frontline Therapy in Chronic Phase Chronic Myeloid Leukemia (CML) [0.03%]
慢性髓性白血病（CML）慢性期一线治疗的演变landscape
Heather R Wolfe,Lindsay A M Rein
Heather R Wolfe
Purpose of review: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by uncontrolled proliferation of mature and maturing granulocytes. The disease is characterized by the presence of transloca...
Katia B Pagnano,Ana Ines Varela,Carolina Pavlovsky et al.
Katia B Pagnano et al.
Purpose of review: Chronic myeloid leukemia (CML) management in developing countries has improved in the last years, but the availability of therapeutic resources, monitoring, reimbursement, and financial issues may be a ...
Nathalie Javidi-Sharifi,Gabriela Hobbs
Nathalie Javidi-Sharifi
Purpose of review: This review will focus on recent and emerging treatment paradigms in chronic phase CML. The discussion of each novel treatment or drug combination will include a brief overview of scientific rational an...
Health-Related Quality of Life of Patients with Chronic Myeloid Leukemia as Measured by Patient-Reported Outcomes: Current State and Future Directions [0.03%]
慢性髓性白血病患者的健康相关生活质量：当前状况及未来方向——基于患者报告的结果测量
Kelly L Schoenbeck,Kathryn E Flynn
Kelly L Schoenbeck
Purpose of review: Tyrosine kinase inhibitors (TKIs) allow many patients with chronic myeloid leukemia (CML) to live normal life spans but have the potential to impact patients' health-related quality of life (HRQOL). Pat...
Ehab Atallah,Kendra Sweet
Ehab Atallah
Purpose of review: Treatment-free remission (TFR) is considered one of the main goals of therapy in patients with CML. Our goal in this paper is to review the current data on TFR, and discuss future directions. ...
A Multi-disciplinary Approach to Managing Chronic Myelogenous Leukemia Patients on Oral Anticancer Therapy at a Large Academic Medical Center [0.03%]
大型学术医疗中心慢性髓性白血病患者口服抗癌药物治疗的多学科管理方法
Angela Canadeo,Mary Fournogerakis,Felicia Zook
Angela Canadeo
Purpose of review: Since the discovery of imatinib, an oral breakpoint cluster region-Abelson murine leukemia tyrosine kinase inhibitor, chronic myelogenous leukemia transformed from a hematologic malignancy primarily tre...
Application of Next-Generation Sequencing-Based Mutational Profiling in Acute Lymphoblastic Leukemia [0.03%]
基于下一代测序的急性淋巴细胞白血病突变谱分析的应用
Ahmed Aleem,Ali R Haque,Gregory W Roloff et al.
Ahmed Aleem et al.
Purpose of review: Recent efforts to characterize hematologic cancers with genetic and molecular detail have largely relied on mutational profiling via next-generation sequencing (NGS). The application of NGS-guided disea...
Sameh Gaballa,Javier Pinilla-Ibarz
Sameh Gaballa
Purpose of review: The treatment landscape of chronic lymphocytic leukemia (CLL) has dramatically changed over the last few years with the introduction of novel targeted agents. Physicians are now faced with several equal...
Philadelphia-Negative Myeloproliferative Neoplasms Around the COVID-19 Pandemic [0.03%]
COVID-19大流行时期的非磷阳性骨髓增生异常症
Tiziano Barbui,Valerio De Stefano
Tiziano Barbui
Purpose of review: Coronavirus disease 2019 (COVID-19) is associated with a high rate of respiratory failure, thromboembolism, bleeding, and death. Patients with myeloproliferative neoplasms (MPNs) are prone to both throm...
Elevating Twitter-Based Journal Club Discussions by Leveraging a Voice-Based Platform: #HemepathJC Meets Clubhouse [0.03%]
利用语音平台提升基于Twitter的期刊俱乐部讨论的质量：#HemepathJC 与 Clubhouse相遇
Aadil Ahmed,Kamran M Mirza,Sanam Loghavi
Aadil Ahmed
Purpose of review: Social media-based scientific journal clubs provide an opportunity to promote published literature to a broader audience and allow robust multi-disciplinary and inter-professional discussion. Hematopath...