James Blake Littlejohn,Kelly Ann Brister
James Blake Littlejohn
Locoregional failure or recurrence after completion of chemoradiation for anal squamous cell carcinoma occurs in up to 27% of patients. Complete restaging with multimodality imaging should be performed to evaluate the extent of local diseas...
Jai Bikhchandani
Jai Bikhchandani
As the treatment path for anal cancers have become highly effective, prevalence of anal cancer survivors needing follow-up has multiplied over the past few decades. Successful long-term care of these patients warrants a robust surveillance ...
Joseph Do Woong Choi,Devansh Shah,Toufic El-Khoury et al.
Joseph Do Woong Choi et al.
Metastatic squamous cell carcinoma of the anal canal is a rare presentation that is suspected in patients with risk factors such as known primary anal cancer, human papillomavirus/human immunodeficiency virus, immunosuppression, smoking, an...
Stevie-Jay Stapler,Drew J Gunnells Jr,Robert H Hollis
Stevie-Jay Stapler
The initial evaluation and workup of anal canal cancer and perianal cancer is the same, but treatment strategies differ based on stage and location of disease. Chemoradiation remains the cornerstone of treatment for anal canal squamous cell...
Prevention of Anal Cancer [0.03%]
肛癌的预防
Maseray S Kamara,Gifty Kwakye
Maseray S Kamara
Anal cancer, though rare, is witnessing an annual increase in incidence, predominantly of squamous cell carcinoma (SCC). Prevention strategies revolve around reducing risk factors such as human papillomavirus (HPV) infection, human immunode...
Julie S Hong,Victoria Yuan,Roger Patron-Lozano et al.
Julie S Hong et al.
Anal cancer is an uncommon disease in a sensitive region of the body that benefits from early and systematic workup and treatment. Main modalities for workup include history, physical examination, and MRI. PET scan and computed tomography s...
Taja Lozar,Evie Carchman
Taja Lozar
The pathophysiology of the development of anal cancer is thought to be linked to chronic inflammation, a possible consequence of infections with human papillomavirus (HPV) or HIV, or inflammation from inflammatory bowel disease. Anal HPV-in...
Wendelyn M Oslock,Daniel I Chu
Wendelyn M Oslock
While anal cancer is somewhat rare, it is increasing in incidence despite improving screening and the human papillomavirus vaccine. Given this, there is growing research into the management of high-grade squamous intraepithelial lesion as w...
Bayley A Jones,Sitaram Chilakamarry
Bayley A Jones
Health disparities are preventable differences in health outcomes that are experienced by disadvantaged patient populations. Disparities in prevention, incidence, treatment, and mortality exist among patients with anal cancer. Factors contr...
Nathan C English,Claire Warden
Nathan C English
Anal cancer is a rare disease, accounting for only 2% of all gastrointestinal tract malignancies. While individuals with advanced age (>50 years) and female sex have an increased risk of anal cancer, there has been a trend toward diagnosis ...