Immunotherapy for Solid Tumors: A Comprehensive Roadmap for the Surgical Oncologist [0.03%]
肿瘤免疫治疗：外科肿瘤医生的全面路线图
Jashodeep Datta
Jashodeep Datta
Immunotherapy for Solid Tumors: A Comprehensive Roadmap for the Surgical Oncologist [0.03%]
肿瘤免疫治疗：外科医生的全面路线图
Timothy M Pawlik
Timothy M Pawlik
Contemporary Management of Immune Checkpoint Inhibitor-related Adverse Events [0.03%]
免疫检查点抑制剂相关毒性反应的现代管理措施
Akshee Batra,Daniel Tuerff,Jose Lutzky
Akshee Batra
Immune checkpoint inhibitors have become one of the pillars of cancer treatment, but may be associated with a wide range of potential adverse effects. In this review, we discuss the presentation and management of immune-related adverse even...
Utility of Circulating Tumor DNA-Based Liquid Biopsies in Patients with Cancer Receiving Immunotherapy [0.03%]
循环肿瘤DNA在免疫治疗中的应用价值
Maria Fernanda Teixeira,Nicole Fahmy,Pashtoon Murtaza Kasi
Maria Fernanda Teixeira
Liquid biopsies offer a promising, noninvasive approach for monitoring and predicting responses to immunotherapy across multiple solid tumors. For the most part these are circulating tumor DNA (ctDNA) based assays. Here, we discuss the biol...
Oncolytic Virotherapy for Solid Tumors: Clinical Advances and Future Directions [0.03%]
溶瘤病毒治疗实体肿瘤：临床进展与未来方向
Palash Asawa,Xena Zheng,Jaime Rafael Merchan
Palash Asawa
Oncolytic viruses (OVs) are naturally occurring or genetically engineered viruses that selectively replicate in and destroy tumor cells while sparing normal tissues. This review provides an overview of the biological basis of OV therapy, in...
Renee R Anderko,Adam Tcharni,Amer H Zureikat et al.
Renee R Anderko et al.
B-cell-directed immunotherapy holds great promise for treating solid tumors, where barriers such as desmoplastic stroma and low immunogenicity have limited the success of established T-cell therapies. Ongoing clinical trials are exploring d...
Identifying Subsets of Patients with Non-immunogenic Gastrointestinal Cancers for Checkpoint Immunotherapy [0.03%]
鉴别出接受检查点免疫疗法的非免疫性胃肠癌症亚型患者群
Cindy M Pabon,Piyush Kumar-Sharma,Benjamin O Spieler et al.
Cindy M Pabon et al.
Efforts to expand immunotherapy benefit in gastrointestinal cancers focus on identifying subsets that may be more responsive to checkpoint blockade, developing combination strategies to overcome immunotherapy resistance, and leveraging the ...
James Bae,Sonia Cohen
James Bae
Immunotherapy has transformed the treatment landscape of some solid tumors, offering durable responses and improved survival across multiple cancer types. As its role in oncology continues to expand, the integration of predictive biomarkers...
Robert J Torphy,Vinod Balachandran,Kevin C Soares
Robert J Torphy
mRNA cancer vaccines offer a promising and flexible platform for personalized immunotherapy, enabling the delivery of tumor-associated or tumor-specific neoantigens to stimulate a strong antigen-specific immune response. This review outline...
Leva Gorji,Ashlee N Seldomridge,Ashley M Holder
Leva Gorji
The human microbiome is composed of distinct microbial communities or ecosystems found throughout the human body, including within unique tumor microenvironments. In this review, we discuss the microbiome's influence on solid tumors, how th...