Genetic Insights Into Nephrolithiasis and Renal Cancer Predisposition: Precision Medicine in Genes, Diagnosis, and Therapy [0.03%]
基因视角下的肾结石和肾脏癌症易感性研究：基因、诊断及治疗方面的精准医疗
Chen-Han Wilfred Wu,Yu-Ren Mike Huang,Hachem Ziadeh et al.
Chen-Han Wilfred Wu et al.
This article explores the role of genetics in kidney stones and kidney cancer predisposition, focusing on monogenic genetic causes that can be identified through genetic testing. We provide a comprehensive review of monogenic causes of kidn...
Should Genetic Testing be Indicated and Implemented for Chronic Kidney Disease of Unknown Cause? [0.03%]
未知原因的慢性肾病应进行基因检测和干预吗？
Julia Jefferis,Amali Mallawaarachchi,Nine Knoers et al.
Julia Jefferis et al.
Advances in genetic testing have attributed many cases of clinically unexplained kidney disease (UKD) to monogenic disorders with such reclarified diagnoses optimizing and individualizing patient care. Patients affected by UKD despite reaso...
Using Large Genomic Biobanks to Generate Insights into Genetic Kidney Disease [0.03%]
利用大型基因组生物样本库生成遗传性肾脏疾病的新见解
Alexander R Chang,Janewit Wongboonsin,Andrew J Mallett et al.
Alexander R Chang et al.
Chronic kidney disease (CKD) affects approximately 9% of the global population, leading to increased risks of end-stage kidney disease (ESKD), cardiovascular disease (CVD), and mortality. Patients with CKD are a huge burden on health care r...
Anthony Batte,Ruth Namazzi,Andrea L Conroy
Anthony Batte
Acute Kidney Injury in Severe Malaria: A Serious Complication Driven by Hemolysis [0.03%]
严重疟疾中的急性肾损伤：溶血驱动的严重并发症
Caroline Kazinga,Olivia Bednarski,Judith Caroline Aujo et al.
Caroline Kazinga et al.
Acute kidney injury (AKI) is a common clinical complication in malaria, with AKI reported across all species that cause severe disease, including Plasmodium falciparum, Plasmodium knowlesi, and Plasmodium vivax. AKI during malaria varies ba...
Michael Lintner-Rivera,Adnan Bhutta,Ruth Namazzi et al.
Michael Lintner-Rivera et al.
Severe malaria remains an important global cause of mortality, particularly in sub-Saharan Africa, where the majority of deaths occur in children under 5 years of age. Hyperkalemia in severe malaria has not been very well reported but is as...
Collins Ojonugwa Mamudu,Rafael Polidoro,Julio Gallego-Delgado
Collins Ojonugwa Mamudu
Malaria-associated acute kidney injury (MAKI) is a critical complication of severe malaria, particularly in infections caused by Plasmodium falciparum, which is responsible for most malaria-related deaths. MAKI affects 40-60% ofs severe mal...
Plasma Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Kidney Injury and Potential Predictor of Hypoxic Brain Injury in Severe Plasmodium falciparum Malaria: Insights From India [0.03%]
恶性疟疾患者血浆NGAL的临床意义：来自印度的证据
Flora Olcott,Cesc Bertran-Cobo,Praveen K Sahu et al.
Flora Olcott et al.
Severe malaria is associated with kidney and brain injury, yet potential mechanisms linking both complications remain understudied. We investigated the associations between kidney and brain injuries in a cohort of Indian adults and children...
Nicholas M Anstey,Matthew J Grigg,Timothy William et al.
Nicholas M Anstey et al.
Acute kidney injury (AKI) complicates non-falciparum malaria, particularly that from Plasmodium knowlesi. AKI (any KDIGO stage) is present in 20-30% of hospitalized patients with knowlesi malaria, with age >45 years having a sixfold risk of...
Kidney Replacement Therapy for Children With Acute Kidney Injury Due to Severe Malaria: A Review of Available Services in Selected African Countries [0.03%]
非洲选定国家儿童严重疟疾急性肾损伤替代肾脏治疗服务的调查
Folake M Afolayan,Nicole O&#x;Brien,Pepe Mfutu Ekulu et al.
Folake M Afolayan et al.
Acute kidney injury (AKI) is a common, life-threatening clinical complication of severe malaria in children associated with increased short- and long-term mortality. Malaria remains a leading cause of child mortality in Africa, where most s...