Paul Muntner
Paul Muntner
Cross-sectional studies have long suggested that renal function declines with age among adults. However, there are limited longitudinal studies with data on within-individual changes in renal function over time. The Baltimore Longitudinal S...
Nada Dimkovic,Dimitrios Oreopoulos
Nada Dimkovic
The number of elderly patients requiring renal replacement therapy will continue to increase in the future. Previously, these patients were believed to have a poor prognosis on renal replacement therapy and therefore they were treated with ...
Donald J Sherrard
Donald J Sherrard
The bone disease seen in our aging dialysis population is a complex mixture of osteoporosis and renal osteodystrophy. Attention must be paid to both of these issues. Hip fractures are increased with aging and this increase is further aggrav...
Edmund Huang,Dorry L Segev,Hamid Rabb
Edmund Huang
There is an increase in the older incident end-stage renal disease population that is associated with an increasing prevalence of end-stage renal disease in the United States. This trend is paralleled by an increasing rate of kidney transpl...
Disorders of lipid metabolism and chronic kidney disease in the elderly [0.03%]
老年人脂质代谢紊乱与慢性肾脏病的关系研究进展
Devasmita Choudhury,Meryem Tuncel,Moshe Levi
Devasmita Choudhury
The growing population of elderly with chronic kidney disease (CKD) is at greater risk for cardiovascular disease given an independent risk of CKD, as well as from added dyslipidemia of aging and renal dysfunction. Changes in lipid metaboli...
Basil O Burney,George L Bakris
Basil O Burney
Many trials focused on cardiovascular outcomes demonstrate that reduction in blood pressure to levels below 140/90 mm Hg reduce cardiovascular events including stroke and myocardial infarction. There are very few such trials, however, in th...
Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons [0.03%]
识别晚期糖基化终产物作为衰老主要的氧化剂来源及其对老年人肾功能减退防治的意义
Helen Vlassara,Jaime Uribarri,Luigi Ferrucci et al.
Helen Vlassara et al.
Aging is characterized by increasing inflammation and oxidant stress (OS). Reduced renal function was present in more than 20% of normal-aged individuals sampled in the National Health and Nutrition Examination Survey (NHANES) cross-section...
Jocelyn Wiggins
Jocelyn Wiggins
Kidney function declines with age in association with the development of age-associated glomerulosclerosis. The well-established structural and functional changes with age are reviewed briefly. The modification of aging pathology by calorie...
Jeff M Sands
Jeff M Sands
Aged people and rats have a reduced ability to maximally concentrate their urine. Many of the key transport proteins that contribute to urine concentrating ability are reduced in the medulla of aged rats. The reductions in the abundances of...
Sexual dimorphism, the aging kidney, and involvement of nitric oxide deficiency [0.03%]
性别二态性、肾脏老化及一氧化氮缺乏的作用
Chris Baylis
Chris Baylis
Females develop less age-dependent loss of renal function, in part because of cardiorenal protective effects of estrogens. The low androgen level in women also may be protective, although the animal and clinical data are controversial. Both...