William J Harb
William J Harb
There is no cure for Crohn disease. Newer treatments, such as biological therapy, have led to an improved quality of life. This article focuses on the surgical management of Crohn disease of the colon, rectum, and anus. Restorative and nonr...
Crohn's Disease of the Foregut [0.03%]
食管克罗恩病
Kurt G Davis
Kurt G Davis
Crohn's disease of the foregut is more common than previously recognized, with up to 40% of patients with Crohn's disease in the distal intestine also having evidence of foregut disease. Esophageal disease is best managed medically with pro...
Panayiotis Grevenitis,Arul Thomas,Nilesh Lodhia
Panayiotis Grevenitis
Surgeons often care for patients with inflammatory bowel disease (IBD) who are receiving therapies that can include 5-ASA compounds, steroids, immunomodulators, and biologics. The goal of these agents is to suppress intestinal inflammation,...
Melanie S Morris,Daniel I Chu
Melanie S Morris
Multiple imaging modalities exist for inflammatory bowel disease. This article explores the use of plain radiographs, contrast radiologic imaging, computed tomography, MRI, ultrasound, and capsule endoscopy. History, technique, indications ...
Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy [0.03%]
炎症性肠病的诊断方式：自身免疫血清学及内镜检查
Clarence Clark,Jacquelyn Turner
Clarence Clark
The evaluation, diagnosis, and monitoring of inflammatory bowel disease (IBD) has improved significantly over the past few decades. However, differentiation and management of the subtypes of IBD (Crohn's disease, ulcerative colitis, and ind...
Inflammatory Bowel Disease: Historical Perspective, Epidemiology, and Risk Factors [0.03%]
炎症性肠病：历史背景、流行病学和危险因素
Talha A Malik
Talha A Malik
Inflammatory bowel disease (IBD) describes a group of closely related yet heterogeneous predominantly intestinal disease processes that are a result of an uncontrolled immune mediated inflammatory response. It is estimated that approximatel...
Christopher L Wolfgang
Christopher L Wolfgang
Ronald F Martin
Ronald F Martin
Personalized Approaches to Gastrointestinal Cancers: Importance of Integrating Genomic Information to Guide Therapy [0.03%]
胃肠肿瘤的个体化治疗：整合基因组信息指导临床决策的重要性
Jin He,Nita Ahuja
Jin He
Cancers are characterized by complex tumor heterogeneity driven by subclones with differential genotypes and phenotypes, which then drives cancer behavior. As genomic strategies become feasible on smaller samples such as biopsies, coupled w...
Lodewijk A A Brosens,G Johan A Offerhaus,Francis M Giardiello
Lodewijk A A Brosens
Colorectal cancer (CRC) is the third most common cancer and the third leading cause of cancer death in men and women in the United States. About 30% of patients with CRC report a family history of CRC. However, only 5% of CRCs arise in the ...