Updates in Management of Locally and Regionally Advanced Basal Cell Carcinoma [0.03%]
局部和区域性晚期基底细胞癌的治疗进展
Kristel Lourdault,Brett Crosby,Jillian McCabe et al.
Kristel Lourdault et al.
Basal cell carcinoma (BCC) is a slow-growing skin cancer that tends to remain localized but that can occasionally grow extensively and penetrate deeper tissues (locally advanced BCC [laBCC]). The first line of treatment for laBCC is surgica...
Norma E Farrow,Danielle M Bello
Norma E Farrow
The management of locoregionally-advanced cutaneous squamous cell carcinoma (laCSCC) is complex and requires a multidisciplinary approach, combining surgical resection, radiotherapy, and systemic therapies. Innovations in immunotherapy, par...
Adrienne B Shannon,Jonathan S Zager
Adrienne B Shannon
Melanoma and Merkel cell carcinoma (MCC) have the potential to develop into advanced, regionally metastatic disease that is not always amenable to resection and is associated with a worse survival. Intralesional therapies, including oncolyt...
Neoadjuvant Therapy in Melanoma: Current Evidence and Future Directions of Investigation [0.03%]
黑色素瘤的新辅助治疗：当前证据及未来研究方向
Mohammad S Farooq,Jerica C Tidwell,Giorgos C Karakousis
Mohammad S Farooq
Neoadjuvant therapy for advance-stage melanoma has had increasing momentum over the past decade owing to several landmark clinical trials. Neoadjuvant therapy has now been shown to confer multiple advantages over adjuvant therapy, including...
Shayna Hollander,Viviana Geron,Kristen E Rhodin et al.
Shayna Hollander et al.
In recent years, effective systemic therapies have emerged for patients with metastatic melanoma. These therapies have also made their way to the perioperative setting, demonstrating improved recurrence-free survival for subsets of individu...
Disparities in Melanoma and Other High-Risk Skin Cancers in the United States: Elders, Minorities, and Rural Populations [0.03%]
美国黑素瘤和其他高风险皮肤癌的差异：老年人、少数族裔和农村人群
Elliot A Asare
Elliot A Asare
People from all racial, social, and economic backgrounds are susceptible to high-risk skin cancers. There are disparities in outcomes, and it is important for surgeons to be aware of the barriers to optimal care faced by their patients so t...
Aikaterini Dedeilia,Tatum Braun,Genevieve M Boland
Aikaterini Dedeilia
Melanomas in special populations constitute a unique challenge. Pediatric melanomas present with atypical histopathological features, and the most common subtypes include congenital nevi-associated, Spitzoid, and conventional melanomas. Alt...
Britney Scott,Aru Panwar
Britney Scott
Approximately 25% of all cutaneous melanomas arise in the head and neck region. Common locations include the face (40%-60%), scalp (14%-49%), neck (20%-29%), and ear (8%-11%) with the most common locations being the occipital scalp and chee...
Evolving Role of Sentinel Lymph Node Biopsy for Melanoma, Merkel Cell, and Squamous Cell Carcinoma [0.03%]
sentinel淋巴结活检在黑色素瘤、Merkel细胞癌和鳞状细胞癌中的作用变迁
Nicole deRosa
Nicole deRosa
Technical advances in lymphoscintigraphy, pathologic immunostaining, and intra-operative mapping in the setting of level 1 evidence have led to the adoption of sentinel lymph node biopsy as an accurate minimally invasive staging procedure. ...
Lindsay A Janes,Christina V Angeles
Lindsay A Janes
Melanoma and Merkel cell carcinoma (MCC) are both lethal types of skin cancer. For early-stage and clinically node negative disease, surgical management is standard of care with wide local excision ± sentinel lymph node biopsy. Many patien...