Degeneration of the stria vascularis in quiet-aged gerbils: Linking structural, cellular and molecular changes to cochlear function [0.03%]
耳鼠血管纹在衰老过程中的退化：结构、细胞和分子改变与耳蜗功能之间的关系
Sonny Bovee,Carolin Jüchter,Georg M Klump et al.
Sonny Bovee et al.
Presbycusis, or age-related hearing loss, is a prevalent condition characterized by progressive auditory decline, significantly impacting quality of life in older adults. While sensorineural damage has been widely studied, degeneration of t...
Choroid plexus volume and its association with cognitive performance across the lifespan: Links to sleep quality and healthy brain aging [0.03%]
脉络丛体积及其一生中与认知表现的关系：睡眠质量和健康大脑衰老的影响
Julia L Becker,M Ethan MacDonald,Kirstan A Vessey et al.
Julia L Becker et al.
The choroid plexus (ChP) is implicated in inflammation and supports the clearance of waste byproducts, particularly those related to the pathogenesis of Alzheimer's disease. Increases in ChP volume have been associated with older age and co...
Cerebral small-vessel disease severity, hypertension, and body mass index forecast striatal dopamine D2-receptor decline rates in aging [0.03%]
脑小血管病严重程度、高血压和体质指数预测衰老过程中黑质多巴胺d2受体衰退速率
Nina Karalija,Vanessa Crine,Anders Wåhlin et al.
Nina Karalija et al.
Normal aging is associated with decline in dopamine function. Factors associated with individual differences in dopamine decline rates remain unclear but are important to map to spare dopamine-related functions, such as cognition. Here we f...
The moderating effect of cognitive reserve on the association between neuroimaging biomarkers and cognition: A systematic review [0.03%]
工作记忆训练对认知储备的调节作用：系统性综述
Lizhi Guo,Yajing Zhou,Hanna Lu et al.
Lizhi Guo et al.
This systematic review aims to investigate the moderating effects of cognitive reserve (CR) on the relationships between cognitive function and multimodal Alzheimer's disease (AD)-signatured brain changes, measured by positron emission tomo...
High estimated pulse-wave velocity is associated with lower brain white matter microstructural integrity twelve years later [0.03%]
脉搏波速度估算值偏高与12年后较低的脑白质微结构完整性相关性较高
Kevin S Heffernan,Derek C Monroe,Andrew S London et al.
Kevin S Heffernan et al.
High pulse wave velocity (PWV), a measure of increased arterial stiffness, is a risk factor for cerebrovascular disease. PWV can be estimated (ePWV) from age and blood pressure (BP). Elevated ePWV is associated with cerebral small-vessel di...
Corrigendum to "Elevation of cytoskeletal protein breakdown in aged Wistar rat brain" [Neurobiol. Aging 27 (2006) 624-632] [0.03%]
关于“Wistar老年大鼠脑细胞骨架蛋白分解的升高”[ Neurobiol. Aging 27 （2006）624-632]的更正通知
Eric Bernath,Nancy Kupina,Ming Cheng Liu et al.
Eric Bernath et al.
Longitudinal non-linear changes in the microstructure of the hippocampal subfields in older adults [0.03%]
老年人海马亚区纵向非线性变化的微结构研究
Ghina Zia,Syed Salman Shahid,Ho-Ching Yang et al.
Ghina Zia et al.
Human brains undergo considerable morphologic variation with age, a primary risk factor for neurodegenerative disorders. While aging often causes neurocognitive decline, its governing biological mechanisms remain unclear. These age-related ...
Age-related increased frontal activation in sentence comprehension reflects inefficiency, not compensation [0.03%]
年龄相关的大脑额叶在句子理解过程中活动增加反映了效率降低而非代偿性增强
Maxime Perron,Hannah Shatzer,Michael Zara et al.
Maxime Perron et al.
Cognitive aging is associated with increased prefrontal cortex (PFC) activity, often interpreted as either a compensatory mechanism or a sign of neural inefficiency. In the context of speech-in-noise perception, it remains unclear whether t...
Hypothalamic imaging in Alzheimer's disease and Lewy body dementia: A systematic review and meta-analysis [0.03%]
阿尔茨海默病和路易体痴呆的下丘脑影像学系统评价和meta分析
Axel As Laurell,Sita N Shah,Masoud Rahmati et al.
Axel As Laurell et al.
Symptoms related to sleep, weight, and endocrine dysfunction are common in Alzheimer's disease (AD) and Lewy body dementia (LBD). The cause of these symptoms is not known, but they may be related to hypothalamic neurodegeneration. We perfor...
Neural network mechanisms of emotional dysregulation in cerebral small vessel disease [0.03%]
脑小血管病情感调节障碍的神经网络机制研究
Olga R Dobrushina,Larisa A Dobrynina,Galina A Arina et al.
Olga R Dobrushina et al.
Cerebral small vessel disease (CSVD) is a prevalent age-related disorder that leads to progressive white matter damage, resulting in cognitive decline and depression. This study explored the neural network mechanisms of emotional dysregulat...