Aziz Shaibani,Fabrizio Benedetti
Aziz Shaibani
Luana Gilio,Diego Centonze,Mario Stampanoni Bassi
Luana Gilio
Dealing with placebo responses in randomized controlled trials for multiple sclerosis presents significant challenges. In studies evaluating both disease-modifying therapies and treatments for symptoms such as spasticity and fatigue, consid...
David A Klodowski,Shira R Goldenholz,Daniel M Goldenholz
David A Klodowski
Epilepsy is a widespread neurologic illness with high morbidity. Further treatments are needed to limit ongoing injury. To demonstrate effectiveness of new treatments, randomized controlled trials comparing adjuvant treatment to placebo are...
Placebo Effects in the Treatment of Depression-Implications for the Psychedelic Renaissance [0.03%]
抑郁症治疗中的安慰剂效应-对迷幻药复兴的影响
Mina Ansari,Sophie I Elliott,Sophie E Holmes et al.
Mina Ansari et al.
The development of novel, rapid-acting treatments and the resurgence of interest in the therapeutic potential of psychedelic-like compounds has stimulated excitement and enthusiasm within the pharmaceutical industry, and provided new hope f...
Surabhi Garg,Tiago Mestre
Surabhi Garg
Parkinson's disease is well documented to be associated with a placebo response. The striatonigral degeneration and resulting dopamine deficiency make it a particularly compelling condition for studying placebo effects, which are most commo...
Placebo Response in Acute and Prophylactic Treatment of Migraine: A Systematic Review and Meta-Analysis Covering 36 Years of Research [0.03%]
偏头痛急性发作和预防性治疗的安慰剂效应：一项涵盖36年研究的系统评价和 meta 分析
N R A Bruijn,E M Huessler,A MaassenVanDenBrink et al.
N R A Bruijn et al.
The authors identified and meta-analyzed 84 acute and 42 prophylactic systematically selected RCTs on antimigraine drugs between 1988 and 2024, with a total of 25,542 placebo recipients, analyzed separately for episodic and chronic migraine...
John M Kelley
John M Kelley
This article explores methods to ethically harness the placebo effect in clinical practice, emphasizing the importance of context, the therapeutic relationship, and patient expectations. It discusses 5 strategies: improving clinician-patien...
Martina Amanzio,Giuseppina Elena Cipriani
Martina Amanzio
The nocebo effect has a significant impact on clinical trials and patient care. It leads to more frequent reports of adverse events, higher drop-out rates, and biased judgements of treatment efficacy. This review summarizes the findings fro...
Didier Bouhassira
Didier Bouhassira
This review article summarizes key aspects of the placebo response in analgesic trials, including its magnitude across pain syndromes, variation with treatments, and predictors of its strength. It also explores the challenges of distinguish...
Carlo Alberto Artusi,Gabriele Imbalzano,Mirta Fiorio et al.
Carlo Alberto Artusi et al.
Functional Neurologic Disorders (FNDs) are prevalent in neurology and emergency settings, causing significant disability and economic burden. Diagnosis relies on positive clinical signs rather than exclusion of organic diseases. Treatment i...