William E Benitz
William E Benitz
Early-onset sepsis remains a major diagnostic problem in neonatal medicine. Definitive diagnosis depends on cultures of blood or other normally sterile body fluids. Abnormal hematological counts, acute-phase reactants, and inflammatory cyto...
Jeanne A Jordan
Jeanne A Jordan
Several molecular testing options are now or will soon be available for diagnosing bloodstream infections in the neonate. The advantages include the speed at which results would be available and the ability to use those results to tailor em...
Rose M Viscardi
Rose M Viscardi
There is accumulating epidemiologic and experimental evidence that intrauterine or postnatal infection with Ureaplasma species is a significant risk factor for adverse pregnancy outcomes and complications of extreme preterm birth such as br...
Group B streptococcal disease in infants: progress in prevention and continued challenges [0.03%]
婴儿B群链球菌病：预防方面的进展与持续存在的挑战
Jennifer R Verani,Stephanie J Schrag
Jennifer R Verani
The burden of early-onset disease caused by group B Streptococcus (GBS) has decreased dramatically in the United States over the past 20 years. Universal culture-based screening at 35 to 37 weeks gestational age and use of intrapartum antib...
The role of proteomics in the diagnosis of chorioamnionitis and early-onset neonatal sepsis [0.03%]
蛋白质组学在胎盘炎和新生儿早期败血症诊断中的作用
Irina A Buhimschi,Catalin S Buhimschi
Irina A Buhimschi
Intrauterine infection is a unique pathologic process that raises the risk for early-onset neonatal sepsis (EONS). By acting synergistically with prematurity, EONS increases the risk for adverse neonatal outcomes, including intraventricular...
Alan T N Tita,William W Andrews
Alan T N Tita
Chorioamnionitis is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis whereas adverse infant outcomes inclu...
Role of innate host defenses in susceptibility to early-onset neonatal sepsis [0.03%]
固有免疫在早期发病型新生儿败血症中的作用
James L Wynn,Ofer Levy
James L Wynn
Neonatal sepsis continues to take a devastating toll globally. Although adequate to protect against invasive infection in most newborns, the distinct function of neonatal innate host defense coupled with impairments in adaptive immune respo...
Preface: early-onset neonatal sepsis-recent advances in diagnosis and prevention [0.03%]
前言：新生儿早期感染性肺炎的诊断和预防的新进展
Karen D Fairchild,Richard A Polin
Karen D Fairchild
Quality improvement in respiratory care: decreasing bronchopulmonary dysplasia [0.03%]
改善呼吸护理的品质：减少支气管肺发育不良
Robert H Pfister,Jay P Goldsmith
Robert H Pfister
Chronic lung disease (CLD) is one of the most common long-term complications in very preterm infants. Bronchopulmonary dysplasia (BPD) is the most common cause of CLD in infancy. Modern neonatal respiratory care has witnessed the emergence ...
Decreasing central line associated bloodstream infection in neonatal intensive care [0.03%]
降低新生儿重症监护病房中心静脉置管相关血流感染发生率
Richard J Powers,David W Wirtschafter
Richard J Powers
Central Line Associated Bloodstream Infections (CLABSIs) have come to be recognized as preventable adverse events that result from lapses in technique at multiple levels of care. CLABSIs are associated with increased mortality and adverse o...