Marcos I Restrepo,Antonio Anzueto
Marcos I Restrepo
Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU adm...
Matthew R Morrell,Scott T Micek,Marin H Kollef
Matthew R Morrell
The diagnosis and management of severe sepsis and septic shock is a complex and dynamic process. Newer evidence-based interventions are constantly being developed and implemented with the purpose of improving morbidity and mortality. Curren...
George Dimopoulos,Matthew E Falagas
George Dimopoulos
Fever is a normal adaptive brain response to infectious and noninfectious causes involving a cytokine-mediated response, the generation of acute phase reactants, and the activation of numerous physiologic, endocrinologic and immunologic sys...
Marin H Kollef,Scott T Micek
Marin H Kollef
Alexandros P Grammatikos,Elpis Mantadakis,Matthew E Falagas
Alexandros P Grammatikos
In pediatric infections, meta-analyses have helped clarify several controversial management issues. Unfortunately, many more aspects remain to be elucidated. This is particularly true in the field of UTIs, the most common serious bacterial ...
Dimitrios K Matthaiou,George Peppas,Matthew E Falagas
Dimitrios K Matthaiou
Meta-analysis on surgical infections may be a useful tool that can provide more accurate outcome estimates than other conventional types of studies. Published meta-analyses in surgical infections tend to focus mainly on the use of antimicro...
Systematic reviews in malaria: global policies need global reviews [0.03%]
系统综述在疟疾研究中的作用：全球政策需要基于全球的综述
Paul Garner,Hellen Gelband,Patricia Graves et al.
Paul Garner et al.
This article highlights systematic reviews of malaria research and what has been learned about applying methods of research synthesis in this particular infectious disease over the last 15 years. It illustrates how systematic reviews have b...
Philip Masson,Sandra Matheson,Angela C Webster et al.
Philip Masson et al.
Urinary tract infections (UTI) are common, and complications result in significant morbidity and mortality and also consume resources. This overview summarizes the current evidence for the prevention and treatment of UTI in adults and child...
Meta-analyses on the prevention and treatment of respiratory tract infections [0.03%]
有关呼吸道感染的预防和治疗的 meta 分析研究进展
Ilias I Siempos,George Dimopoulos,Matthew E Falagas
Ilias I Siempos
The authors have endeavored to provide an overview of meta-analyses on the prevention and treatment of RTIs. Meta-analyses are useful tools to address clinically relevant questions; however, their inherent limitations should be taken into c...
Lise L Gluud,Christian Gluud
Lise L Gluud
This article summarizes the meta-analyses of interventions for viral hepatitis A, B, and C. Some of the interventions assessed are described in small trials with unclear bias control. Other interventions are supported by large, high-quality...