Efficacy and Safety of Adjunctive Bile Acid Sequestrant Therapy for Thyrotoxicosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
bile酸树脂治疗甲状腺毒症有效性和安全性的系统评价和meta分析
Diego Moreno Watashi,Aastha Sehgal,Flavia Tejada Frisancho et al.
Diego Moreno Watashi et al.
Background: Bile acid sequestrants have been reported to reduce serum thyroid hormone levels by binding T4 and T3 excreted into the intestinal lumen, preventing their reabsorption into the systemic circulation and interrupting the enterohep...
Understanding the Factors That Influence Shared-Decision Making Around Surgical Resection of Low-Risk Thyroid Cancers: A Prospective Qualitative Study [0.03%]
影响低危甲状腺癌患者手术决策因素的前瞻性定性研究
Wanding Yang,Oliver Skan,Simon N Rogers et al.
Wanding Yang et al.
Background: International guidelines now recommend adopting individualized approaches which consider patient preferences when deciding the extent of surgical resection for low-risk differentiated thyroid carcinoma (LRDTC). Information-shari...
Subcutaneous Levothyroxine Administration in Treatment of Refractory Primary Hypothyroidism: A Case Report [0.03%]
左旋甲状腺素皮下注射治疗难治性原发性甲状腺功能减退症的一例报告
Lawrence Siu-Chun Law,Nicholas Wei Xiang Kuu,Melissa Hui Ting Leong et al.
Lawrence Siu-Chun Law et al.
Background: We assessed the effectiveness of administering subcutaneous levothyroxine in a medically complex patient, a 51-year-old male who previously underwent total thyroidectomy for papillary thyroid carcinoma. His thyrotropin (TSH) wor...
Thyroglobulin Cutoffs after Total Thyroidectomy Without Radioiodine in Low- to Intermediate-Risk Thyroid Cancer: A Multicenter Cohort Study [0.03%]
甲状腺切除术后未进行放射性碘治疗的低至中危甲状腺癌患者血清 thyroglobulin 截断值:多中心队列研究
Mijin Kim,Eun Kyung Lee,Kyeong Jin Kim et al.
Mijin Kim et al.
Background: The prognostic value of unstimulated serum thyroglobulin (Tg) levels for structural recurrence in patients with low- to intermediate-risk differentiated thyroid cancer (DTC) who underwent total thyroidectomy but did not receive ...
Corticosteroids Versus Teprotumumab for the Treatment of Thyroid Eye Disease. Does Either Mitigate the Need for Additional Treatments? [0.03%]
皮质类固醇与 teprotumumab 治疗甲状腺眼病的疗效比较:哪种疗法能减少其他治疗需求?
Suyoung Choi,Sarthak Vinay Shah,Patcharaporn Chandraparnik et al.
Suyoung Choi et al.
Background: The treatment paradigm for thyroid eye disease (TED) in the United States has shifted from corticosteroids toward targeted therapies such as teprotumumab. However, it remains unknown whether teprotumumab decreases the need for s...
Addressing the Impact on the Patient's Quality of Life Following Treatment for Hyperthyroidism and Subsequent Weight Gain [0.03%]
治疗甲状腺功能亢进及后续体重增加对患者生活质量的影响
Yuji Nagayama,Hiroyuki Yamashita
Yuji Nagayama
Functional Loss of the Tumor Suppressor Gene RASAL1 Through Formation of Aberrant Splice Variant RASAL1-004 as a Novel Oncogenic Mechanism in Thyroid Cancer [0.03%]
甲状腺癌中通过产生异常剪接变异体RASAL1-004失活抑癌基因RASAL1的新型致癌机制
Jing Liao,Junwei Song,Zhuo Wang et al.
Jing Liao et al.
Background: RASAL1 is a prominent tumor suppressor gene through inactivating RAS, whose functional loss has been widely found to play an important role in thyroid cancer and occurs usually through its genetic and epigenetic inactivation. In...
Weight Gain after Treatment of Hyperthyroidism is Associated with Impairment of Quality of Life [0.03%]
甲亢治疗后的体重增加影响生活质量
Angelos Kyriacou,Alexis Kyriacou,Demetris Lamnisos et al.
Angelos Kyriacou et al.
Background: There is evidence of quality of life (QoL) impairment and weight gain in treated hyperthyroidism. It is not known whether treatment-related weight gain is associated with QoL impairment in this patient group of this cohort. Our ...
Are Total Thyroidectomy and Adjuvant Radioactive Iodine Treatment Required in All Patients with N1b Intermediate-High Risk Papillary Thyroid Carcinoma? [0.03%]
所有N1b期中高危甲状腺乳头状癌患者都需要全切和术后放射性碘治疗吗?
Takashi Fujiwara,Nozomu Kofuji,Yo Kishimoto et al.
Takashi Fujiwara et al.
Background: The optimal extent of surgery and the role of radioactive iodine (RAI) in patients with papillary thyroid carcinoma (PTC) with lateral neck metastasis (cN1b) remain controversial. We aimed to evaluate the oncologic outcomes of l...