Surgical Morbidity and Short-Term Oncologic Status after Prophylactic-Intent Thyroidectomy in a Cohort of Children with MEN2 from the Multicenter GTE ENDOCAN-RENATEN Study [0.03%]
一项针对MEN2儿童患者的多中心研究：GTE ENDOCAN-RENATEN队列中预防性甲状腺切除术后的外科并发症和短期肿瘤状态
Isaline Morard,Frédéric Castinetti,Isabelle Oliver Petit et al.
Isaline Morard et al.
Background: Children carrying germline RET mutations associated with multiple endocrine neoplasia type 2 (MEN2) are at high risk of developing medullary thyroid carcinoma (MTC). Prophylactic-intent thyroidectomy is recomm...
Liver, Portal, and Systemic Thyroid Hormone Concentrations in End-Stage MASH Reveal Distinct Roles for T3/rT3 Ratio and T4 [0.03%]
终末期MASH小鼠的肝脏、门脉和全身甲状腺激素浓度揭示了T3/rT3比率和T4的不同作用
Xinru Zhang,Zhixiong Ying,Tonguç Utku Yilmaz et al.
Xinru Zhang et al.
Background: The liver is a central organ in thyroid hormone (TH) metabolism, mediating the conversion of thyroxine (T4) to bioactive triiodothyronine (T3) via type 1 deiodinase and the clearance of reverse T3 (rT3). Selec...
Early Outcomes of Thermal Ablation for Low-Risk Papillary Thyroid Cancer: A Multicenter Study from Latin American Interventional Thyroidology Association (LAITA) [0.03%]
拉丁美洲甲状腺介入协会(LAITA)关于低危乳头状甲状腺癌热消融近期疗效的多中心研究
Juan Pablo Dueñas,Nathalia Buitrago-Gómez,Antonio Rahal et al.
Juan Pablo Dueñas et al.
Background: Thermal ablation has emerged as a minimally invasive alternative for low-risk papillary thyroid cancer (PTC). However, data from Latin America remain scarce. This multicenter study evaluated the early efficacy...
Central Thyroid Hormone Deprivation Disrupts Cortical Cilia and Oligodendrocyte Lineage in an Allan-Herndon-Dudley Syndrome Mouse Model [0.03%]
中枢甲状腺激素剥夺破坏艾伦-赫尔南德-戴利综合征小鼠模型皮层纤毛和少突胶质细胞谱系
Anna Molenaar,Ekta Pathak,Miriam Bernecker et al.
Anna Molenaar et al.
Background: Allan-Herndon-Dudley syndrome (AHDS) is an X-linked neurodevelopmental disorder caused by loss of the thyroid hormone (TH) transporter MCT8, resulting in central TH deprivation and disrupted cortical maturatio...
Maternal Third-Trimester TRAb Is Associated with Neonatal Thyroid Dysfunction and 24-Month Offspring Neurodevelopment: A Bidirectional Cohort Study [0.03%]
母体第三 trimester TRAb 与新生儿甲状腺功能障碍及后代 24 月龄神经发育的关系：双向队列研究
Jianing Zhang,Yu Wang,Guoyu Sun et al.
Jianing Zhang et al.
Background: Maternal Graves' disease (GD) has been linked to neonatal thyroid dysfunction, but its relationship with offspring neurodevelopment remains unclear. We examined the associations of maternal GD-related thyroid ...
Prognostic Stratification of Brain Metastases from Nonanaplastic Follicular Cell-Derived Thyroid Carcinoma: Results of an International Multicenter Retrospective Study [0.03%]
国际多中心回顾性研究的预后分层：非小细胞乳头状衍生甲状腺癌脑转移的结果
Antonio Prinzi,Evert F S van Velsen,Jolanta Krajewska et al.
Antonio Prinzi et al.
Background: Brain metastases (BMs) from nonanaplastic follicular cell-derived thyroid carcinoma (hereinafter referred to as non-ATC) are rare and not well characterized, with limited evidence guiding treatment and prognos...
Micro-Costing Analysis of Thyroid Radiofrequency Ablation Compared with Hemithyroidectomy in Outpatient and Inpatient Settings [0.03%]
门诊和住院患者甲状腺射频消融与半甲状腺切除术的微成本分析
Harrison Gao,David Forner,Ben B Levy et al.
Harrison Gao et al.
Background: Thyroid radiofrequency ablation (RFA) is a minimally invasive treatment for thyroid nodules. However, the health system costs of thyroid RFA are not well defined in the current literature. As its use expands, ...
The Treatment of Advanced Thyroid Cancer Using Pemetrexed Monotherapy or with Platinum-Based Chemotherapy [0.03%]
单用培美曲塞或联合以铂为基础的化疗治疗甲状腺癌的效果研究
Laura Boucai,Rodrigo Fano,Eric J Sherman et al.
Laura Boucai et al.
Background: Mortality from thyroid cancer is driven by advanced forms of the disease. While second-line therapies have been approved and recognized in thyroid cancer guidelines, development of toxicity and resistance requ...
Marta Pérez-López,Petros Perros
Marta Pérez-López
Background: Graves' orbitopathy (GO) affects approximately 0.1% of the population. GO in anophthalmic patients is extremely rare and may provide insights into the pathogenesis of this disease. ...
Shorter Versus Standard Antithyroid Drug Therapy in Graves' Disease with Lower Baseline Thyrotropin Receptor Antibody (TRAb) Levels: Relapse Outcomes from a Propensity-Weighted Analysis [0.03%]
基线甲状腺刺激抗体水平较低的Graves病患者短程与常规抗甲状腺药物治疗复发结局的倾向加权分析
Salman Razvi,Mia Holley,Hannah Wheeler et al.
Salman Razvi et al.
Background: The optimal duration of antithyroid drug (ATD) therapy in Graves' disease is uncertain. Although guidelines recommend 12-18 months, shorter courses may be sufficient in selected patients. We evaluated whether ...