Trends in the Incidence, Organization of Care, and Surgical Treatment of Medullary Thyroid Cancer: A Population-Based Study [0.03%]
基于人群的甲状腺髓样癌发病、治疗组织和手术趋势研究
Eline C Jager,Madelon J H Metman,Inger A C Timmenga et al.
Eline C Jager et al.
Background: Medullary thyroid cancer (MTC) is a rare cancer with variable disease course. To enable optimal care, centralization and consensus guidelines are essential. This study describes trends in the incidence, organization of care, sur...
Subsequent Thyroid Carcinomas in Children and Adolescents Registered in the German MET Consortium (1997-2023) [0.03%]
德国MET联盟(1997-2023年)登记的儿童和青少年继发性甲状腺癌患者数据
Marina Kunstreich,Cecile M Ronckers,Kerstin Lorenz et al.
Marina Kunstreich et al.
Introduction: Among childhood cancer survivors, the cumulative incidence rate of differentiated thyroid carcinomas (DTCs) is estimated to be 8-11%. Although the association of DTC with prior radiotherapy is well-studied, the association wit...
Radiofrequency Ablation for Solitary Autonomously Functioning Thyroid Nodules: Multicenter Study from Latin America [0.03%]
射频消融治疗拉丁美洲单发自主性甲状腺结节的多中心研究
Juan Pablo Dueñas,Nathalia Buitrago-Gómez,Antonio Rahal et al.
Juan Pablo Dueñas et al.
Background: Autonomously functioning thyroid nodules (AFTNs) represent ∼5% of all thyroid nodules and often necessitate definitive treatments such as surgery or radioiodine (131I), both of which have inherent risks. Radiofrequency ablation...
Association Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Thyroid Cancer [0.03%]
与甲状腺癌相关的代谢功能异常相关脂肪型肝病的关联研究
Sang Yi Moon,Minkook Son,Jung-Hwan Cho et al.
Sang Yi Moon et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a hepatic manifestation of metabolic syndrome. This study investigated the association between newly developed nomenclature MASLD and the risk of thyroi...
Changes in the Volume and Diameter of Benign Thyroid Nodules: A 10-Year Follow-Up Study [0.03%]
良性甲状腺结节体积和直径的变化：一项为期10年的随访研究
Murat Faik Erdoğan,Adile Begüm Bahçecioğlu,Fatma Avcı Merdin et al.
Murat Faik Erdoğan et al.
Background: The incidence of asymptomatic thyroid nodules has risen enormously, with > 90% being benign. Despite limited long-term data, significant nodule growth (SNG) is common. Guidelines recommend cytology reevaluation if SNG occurs. Ou...
Biphasic Effect of Thyroid Hormone on Megakaryopoiesis and Platelet Production [0.03%]
甲状腺激素对巨核细胞生成和血小板生成的双相效应
Baichuan Xu,Xianpeng Ye,Zhaoyang Wen et al.
Baichuan Xu et al.
Background: Abnormal platelet counts are frequently observed in patients with thyroid dysfunction; however, the direct impact of thyroid hormones on thrombopoiesis remains largely undefined. Methods: This study elucidates the dose-response ...
Preliminary Report Examining Efficacy and Safety of Radiofrequency Ablation for the Treatment of Skin-Involving Recurrent Thyroid Cancer [0.03%]
射频消融治疗累及皮肤的复发性甲状腺癌的疗效和安全性的初步研究报告
Hye Hyeon Moon,Jung Hwan Baek,Sae Rom Chung et al.
Hye Hyeon Moon et al.
Background: This study assessed the efficacy and safety of ultrasound (US)-guided radiofrequency ablation (RFA) for treatment of skin-involving recurrent thyroid cancer. Methods: In this retrospective case series study, 43 patients (mean ag...
High Prevalence of TBC1D12 5'UTR Mutations in Anaplastic Thyroid Cancer [0.03%]
甲状腺癌中TBC1D12 5' UTR突变的高流行率
Guanghui Hu,Junyu Xue,Ju Yu et al.
Guanghui Hu et al.
Background: Anaplastic thyroid cancer (ATC) is a rare but one of the most lethal types of human cancer. Although increasing evidence demonstrated that ATC tumors had a high mutation burden, little is known about the aberrancy of the noncodi...
Performance of Afirma Genomic Sequencing Classifier in Binary Subcategories of Atypia of Undetermined Significance Thyroid Nodules: Single Versus Repeat Diagnosis [0.03%]
Afirma基因测序分类器在未定意义的甲状腺结节二元亚类中的表现：单次与重复诊断结果比较
Xiaobing Jin,David T Broome,Madelyn Lew et al.
Xiaobing Jin et al.
Background: Afirma Genomic Sequencing Classifier (GSC) testing has been utilized for further risk stratification of thyroid nodules categorized as atypia of undetermined significance (AUS). The 2023 Bethesda system subcategorizes AUS diagno...
Efficacy and Safety of Selective RET Inhibitors in Patients with Advanced Hereditary Medullary Thyroid Carcinoma [0.03%]
选择性RET抑制剂治疗遗传性髓样甲状腺癌的疗效和安全性评估
Sarah Hamidi,Sireesha Yedururi,Mimi I Hu et al.
Sarah Hamidi et al.
Background: Two selective RET inhibitors (RETis) are effective in treating REarranged during Transfection (RET)-altered medullary thyroid carcinoma (MTC), but clinical trials did not distinguish responses between hereditary MTC (hMTC) and s...