Summary of the Year in Review Lectures at the 2024 Annual Meeting of the American Thyroid Association [0.03%]
2024年美国甲状腺协会年会年终回顾讲座摘要
Douglas Forrest,Jennifer A Sipos,Elizabeth G Grubbs
Douglas Forrest
Transcriptome of Anaplastic Thyroid Cancer Reveals Two Molecular Subtypes with Distinct Tumor Microenvironment and Prognosis [0.03%]
甲状腺癌转录组揭示了两种具有不同肿瘤微环境和预后的分子亚型
Hyunjong Byun,Han Sai Lee,Young Shin Song et al.
Hyunjong Byun et al.
Background: Although patients with anaplastic thyroid cancer (ATC) generally have a poor prognosis and there are currently no effective treatment options, survival and response to therapy vary between patients. Genomic and transcriptomic pr...
Long-Term Outcomes in Radioiodine-Resistant Follicular Cell-Derived Thyroid Cancers Treated with [177Lu]Lu-DOTAGA.FAPi Dimer Therapy [0.03%]
治疗放射性碘抵抗的滤泡细胞衍生甲状腺癌的[177Lu]Lu-DOTAGA.FAPi二聚体疗法的长期疗效评估
Sanjana Ballal,Madhav Prasad Yadav,Swayamjeet Satapathy et al.
Sanjana Ballal et al.
Aim: The study aimed to analyze the long-term outcomes of [177Lu]Lu-DOTAGA.FAPi dimer therapy in individuals diagnosed with radioiodine-resistant (RAI-R) follicular cell-derived thyroid cancer. Materials and Methods: In this retrospective s...
Strength of Genetic Associations with Thyrotropin Values Differs Between Populations with Similarity to African and European Reference Populations [0.03%]
甲状腺素血值的遗传关联强度在接近非洲和欧洲参照人群的群体间有所不同
Alisha N Wade,Lindsay Guare,Mahtaab Hayat et al.
Alisha N Wade et al.
Background: Epidemiological data suggest the population distribution of thyrotropin (TSH) values is shifted toward lower values in self-identified Black non-Hispanic individuals compared with self-identified White non-Hispanic individuals. ...
Proteomic Profiling of Medullary Thyroid Cancer Identifies CAPN1 as a Key Regulator of NF1 and RET Fueled Growth [0.03%]
蛋白质组学鉴定出CAPN1是NF1和RET驱动下髓样甲状腺癌生长的关键调节因子
Eshan Khan,Hannah Hylton,Neel Rajan et al.
Eshan Khan et al.
Background: Medullary thyroid cancer (MTC) is a frequently metastatic tumor of the thyroid that develops from the malignant transformation of C-cells. These tumors most commonly have activating mutations within the RET or RAS proto-oncogene...
Tumor-Infiltrating Lymphocytes Assessed Using the International TILs Working Group System Are Not Prognostic in Medullary Thyroid Cancer [0.03%]
采用国际肿瘤浸润淋巴细胞工作组系统评估的肿瘤浸润淋巴细胞不能作为髓样甲状腺癌预后的标志
Alexander Papachristos,Lydia Zhou,Amy Sheen et al.
Alexander Papachristos et al.
Background: Tumor-infiltrating lymphocytes (TILs) are a protective prognostic factor in several solid tumors and predict response to immune checkpoint inhibitor therapy. The prognostic impact of TILs in medullary thyroid cancer (MTC) is poo...
Radiofrequency Ablation of Low-Risk Papillary Thyroid Microcarcinoma: A Retrospective Cohort Study Including Patients with More than 10 Years of Follow-up [0.03%]
低危乳头状甲状腺微小癌射频消融的回顾性队列研究（随访时间超过10年）
So Yeong Jeong,Sun Mi Baek,Suyoung Shin et al.
So Yeong Jeong et al.
Background: The longest reported follow-up for thermal ablation of papillary thyroid microcarcinoma (PTMC) is 5 years. We evaluated the long-term efficacy and safety of radiofrequency ablation (RFA) in patients with low-risk PTMC with clini...
Letter to the Editor: New Current Procedural Terminology Codes for Radiofrequency Ablation of Thyroid Nodules Will Negatively Affect American Patients According to the Executive Council of the North American Society for Interventional Thyroidology [0.03%]
致编辑的信：北美放射频率消融甲状腺结节新现行程序术语编码将根据北美介入性甲状腺学会执行委员会的观点损害美国患者利益
Jonathon O Russell,Timothy Huber,Julia Noel et al.
Jonathon O Russell et al.
High Rates of Unnecessary Surgery for Indeterminate Thyroid Nodules in the Absence of Molecular Test and the Cost-Effectiveness of Utilizing Molecular Test in an Asian Population: A Decision Analysis [0.03%]
缺乏分子检测下不确定甲状腺结节的过度手术及在亚洲人群进行分子检测的经济学分析：决策树模型研究
Man Him Matrix Fung,Ching Tang,Gin Wai Kwok et al.
Man Him Matrix Fung et al.
Objectives: Cytologically indeterminate thyroid nodules (Bethesda class III or IV) carry a 10-40% risk of malignancy. Diagnostic lobectomies are frequently performed but negative surgeries incur unnecessary costs on the healthcare system, p...
Statin Use and the Risk of Graves' Orbitopathy: A Nationwide Population-Based Cohort Study [0.03%]
他汀类药物使用与Graves眼病风险的相关性：基于全国人群的队列研究
Yu-Tsung Chou,Chun-Chieh Lai,Chung-Yi Li et al.
Yu-Tsung Chou et al.
Background: Statin use is reported to reduce the risk of Graves' orbitopathy (GO) in Western populations. However, study regarding the protective effect of statins against GO in Asians with Graves' disease (GD) is scarce. This study aims to...