Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice [0.03%]
甲状腺素治疗可抑制脑外伤后的星形胶质细胞增生并促进神经元恢复：小鼠模型中的作用及机制研究
Yan-Yun Liu,Wenling Chen,Paola Aguiari et al.
Yan-Yun Liu et al.
Background: Traumatic brain injury (TBI) disrupts blood supply, damages neurons and glial cells, and reduces local activation of the prohormone thyroxine (T4) to the active form, triiodothyronine. We treated mice with T4 post-TBI to evaluat...
2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer [0.03%]
美国甲状腺协会2025年分化型甲状腺癌成人患者管理指南
Matthew D Ringel,Julie Ann Sosa,Zubair Baloch et al.
Matthew D Ringel et al.
Background: Differentiated thyroid cancer (DTC) is the most prevalent cancer of thyroid and is among the most frequently diagnosed cancers in the United States. The practice guidelines of the American Thyroid Association (ATA) for DTC manag...
First-in-Human Clinical Feasibility Study of Ablation of Benign Thyroid Nodules Using Nanosecond Pulsed Field Ablation [0.03%]
纳秒脉冲场消融治疗良性甲状腺结节首次人体可行性研究
Stefano Spiezia,Chiara Offi,Claudia Misso et al.
Stefano Spiezia et al.
Background: Thyroid nodules are common in the general population, and most are benign. Thyroidectomy remains the most common treatment for symptomatic benign thyroid nodular disease. The objective of this study is to determine if a novel, c...
Disease-Specific and Histological Outcomes of Preoperative TERT Promoter Mutation Detected in Isolation or in Combination with Other Mutations in Thyroid Neoplasms [0.03%]
甲状腺肿瘤术前单独或联合其他基因突变检测到的TERT启动子突变的特异性和组织学结果
Michael Calcaterra,Alaa Sada,Esra Karslioglu-French et al.
Michael Calcaterra et al.
Background: TERT promoter mutations in thyroid cancer are associated with aggressive disease, including recurrence, distant metastasis, and disease-related mortality. We aim to assess histological and disease-related outcomes when TERT muta...
Patient-Reported Tolerability of Selpercatinib Compared to Cabozantinib/Vandetanib: A Secondary Analysis of the LIBRETTO-531 Randomized-Controlled Trial in RET-Mutant Medullary Thyroid Cancer [0.03%]
塞利帕利汀与卡博替尼/凡德他尼的患者耐受性比较：LIBRETTO-531随机对照试验的事后分析在RET突变型髓样甲状腺癌中的应用
Rossella Elisei,Lori J Wirth,Jaume Capdevila et al.
Rossella Elisei et al.
Background: Progression-free survival (PFS) may not fully capture the impact of treatment on patients, especially in cancers with longer natural histories and thus, could be complemented by robust measures of patient-reported tolerability (...
Neoadjuvant Therapy with Multikinase Inhibitors for Locally Advanced Differentiated Thyroid Cancer: A Systematic Review [0.03%]
分化型局部晚期甲状腺癌多靶点酪氨酸激酶抑制剂新辅助治疗的系统评价
Justin Bauzon,Guillermo Ponce de Leon-Ballesteros,Eddy Lincango et al.
Justin Bauzon et al.
Background: The use of multikinase inhibitors (MKIs) in thyroid cancer has been established to downsize and facilitate resection of poorly differentiated, differentiated high-grade, anaplastic, and medullary thyroid cancer. Case reports and...
Early Statin Use Following Diagnosis of Graves' Disease Is Associated with a Reduced Risk of Moderate-to-Severe Graves' Orbitopathy in Middle-Aged Adults: Evidence from a Nationwide Taiwanese Cohort [0.03%]
台湾全国性资料库的世代研究：中年成人诊断出葛瑞夫兹病后早期使用他汀与较低的莫德塞维葛瑞夫兹眼症风险有关联
Yu-Tsung Chou,Chun-Chieh Lai,Chung-Yi Li et al.
Yu-Tsung Chou et al.
Background: Statin use is associated with a reduced risk of Graves' orbitopathy (GO). However, whether the timing of initiating statin treatment after the diagnosis of Graves' disease (GD) affects the association between statin and GO risk ...
Dynamic Risk Assessment Using Unstimulated Serum Thyroglobulin Level and Thyroglobulin Doubling Rate after Total Thyroidectomy for Papillary Thyroid Carcinoma [0.03%]
基于未刺激血清甲状腺球蛋白水平和手术后甲状腺球蛋白倍增时间的分化型甲状腺癌复发风险分层及随访策略动态评估模型研究
Yasuhiro Ito,Akira Miyauchi,Masashi Yamamoto et al.
Yasuhiro Ito et al.
Background: Thyroglobulin (Tg), stimulated or unstimulated by recombinant human thyrotropin (TSH), is a static marker of recurrent or persistent disease, and the Tg-doubling rate (Tg-DR) is a dynamic prognostic factor. This study evaluated ...
Henry B Burch
Henry B Burch