Rebecca E Lacher,Douglas H Smith
Rebecca E Lacher
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury [0.03%]
儿童创伤性脑损伤与骨科损伤后脑源性神经营养因子基因的差异DNA甲基化现象观察
Lacey W Heinsberg,Aboli Kesbhat,Bailey Petersen et al.
Lacey W Heinsberg et al.
Pediatric traumatic brain injury (TBI) triggers biological changes that may differ from those observed in non-brain injuries. Brain-derived neurotrophic factor (BDNF) DNA methylation (DNAm) may serve as a novel, dynamic biomarker of the bra...
Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs [0.03%]
用于青少年猪旋转和震荡性创伤性脑损伤模型的血浆和影像生物标志物变化研究
Samuel S Shin,Kevin D Browne,Angela N Viaene et al.
Samuel S Shin et al.
Given the heterogeneity of traumatic brain injury (TBI), the development of a therapeutic strategy has been difficult despite decades of research. To develop an accurate classification system to guide individualized treatment, new protein b...
YAP Regulates Microglial Anti-Inflammatory Responses and Alleviates Cognitive Impairment Through the IL-33/ST2 Pathway after Traumatic Brain Injury [0.03%]
YAP通过调节脑创伤后的IL-33/ST2通路调控小胶质细胞的抗炎反应并改善认知功能损伤
Ran Zhao,Sheng-Qing Gao,Xue Wang et al.
Ran Zhao et al.
Traumatic brain injury (TBI) is a neurological disease that seriously endangers human life and has a poor prognosis. In particular, neuroinflammation during secondary injury after TBI affects the course of TBI, and interleukin-33 (IL-33) pl...
Artificial Intelligence Chatbot Responses to Patient Queries on Traumatic Brain Injury: An Expert Assessment of Reliability and Accuracy [0.03%]
人工智能聊天机器人对脑损伤患者问题的回答：可靠性和准确性的专家评估
Patrick Schuss,Andreas S Gonschorek,Michael Kämper et al.
Patrick Schuss et al.
The increasing use of artificial intelligence-driven chatbots for medical queries requires a systematic evaluation of their accuracy, reliability, and potential role in patient education. This study assesses the performance of three widely ...
Administration of a Novel Peptide Derived From Thrombospondin Repeat Sequences Enhances Recovery after Cervical Spinal Cord Injury [0.03%]
一种新颖的血小板源性衍生肽在颈椎脊髓损伤后促进功能恢复
Nayaab Punjani,Sighild Lemarchant,Svetlana Altamentova et al.
Nayaab Punjani et al.
Spinal cord injury (SCI) is a debilitating condition resulting in the loss of sensorimotor functioning at and below the site of injury. Despite advances in the treatment and management of SCI, there are no current approved pharmacological t...
The Impact of Mild Traumatic Brain Injury Sustained with Blast or Nonblast Mechanism During Combat or Noncombat Deployment on Community Reintegration [0.03%]
战斗或非战斗部署期间暴露于爆炸或非爆炸机制的轻度脑外伤对社区重新融入的影响
Rosemay A Remigio-Baker,Clara Dismuke-Greer,Mary Jo Pugh et al.
Rosemay A Remigio-Baker et al.
Community reintegration serves an integral role to enhance veterans' quality of life as they transition to civilian life. Unsuccessful reintegration after military separation may contribute to the relative increase in adverse outcomes such ...
Development of Prognostic Models for Bladder and Bowel Dysfunction in Traumatic Spinal Cord Injury Patients Using Machine Learning [0.03%]
基于机器学习的脊髓损伤患者膀胱和肠道功能预后模型的发展
Takaki Kitamura,Satoshi Maki,Takeo Furuya et al.
Takaki Kitamura et al.
Recent advancements in machine learning have increased studies predicting neurological outcomes following spinal cord injury (SCI). However, there is limited research on predictive models for bladder and bowel dysfunction outcomes postinjur...
Biofluid Biomarkers of Acute Traumatic Spinal Cord Injury: A Systematic Review [0.03%]
急性脊髓损伤的生物标志物：系统性综述
Ericka A Schaeffer,Adam S Levy,Emily L Errante et al.
Ericka A Schaeffer et al.
Traumatic spinal cord injury (TSCI) is a debilitating disease that results in a heterogeneous set of symptoms. This includes secondary inflammatory mechanisms, which can perpetuate injury to the spinal cord, as well as negatively affect oth...
Frontal Burr-Hole Compared with Parietal Burr-Hole in the Management of Chronic Subdural Hematoma: A Single-Center, Randomized Controlled, Noninferiority Trial [0.03%]
慢性硬膜下血肿治疗中前叶钻孔与顶叶钻孔对照的非劣效性随机试验研究
Ping Chen,Pengcheng Ou,Zhenkun Xiao et al.
Ping Chen et al.
With the aging population, symptomatic chronic subdural hematoma (CSDH) is becoming increasingly prevalent in neurosurgical practice. While burr-hole drainage remains the mainstay treatment, the optimal drilling site remains controversial. ...