A Stable mRNA-Based Novel Multi-Epitope Vaccine Designs Against Infectious Heartland Virus by Integrated Immunoinformatics and Reverse Vaccinology Approaches [0.03%]
基于稳定mRNA的集成免疫信息学和反向疫苗学方法设计对抗传染性心脏兰德病毒的新多表位疫苗
Awais Ali,Syed Luqman Ali
Awais Ali
The Heartland virus (HRTV) is a tick-borne human pathogenic phlebovirus that primarily causes leukopenia and thrombocytopenia. It is transmitted by Amblyomma americanum type of tick, that is, notable for their aggressive biting behavior, af...
Advances in the Epidemiology, Pathogenesis, Diagnostic Methods, and Vaccine Development of Dengue Fever: A Comprehensive Review [0.03%]
登革热流行病学、发病机制、诊断方法及疫苗开发的最新进展：全面综述
Boqi Dong,Sisi Feng,Xianmin Feng
Boqi Dong
Dengue fever (DF) is a common mosquito-borne viral infection caused by any of the four dengue virus (DENV) serotypes. In recent years, the global incidence of DF has risen rapidly, which has widely threatened the health of millions of peopl...
Identification of Biomarkers for Response to Interferon in Chronic Hepatitis B Based on Bioinformatics Analysis and Machine Learning [0.03%]
基于生物信息学分析和机器学习的慢性乙型肝炎干扰素反应标志物的识别
Xiaoqin Yuan,Mingsha Zhou,Xing Liu et al.
Xiaoqin Yuan et al.
Interferon (IFN) is a pivotal agent against hepatitis B virus (HBV) in clinic, but there is a lack of accurate biomarkers to predict the response to IFN therapy in patients with chronic hepatitis B (CHB). Our study aimed to investigate pote...
Marco Iuliano,Giovanna Romeo,Giorgio Mangino
Marco Iuliano
The True Extent of Avian Influenza Virus Infections: Knowns and Unknowns [0.03%]
禽流感病毒感染的真实程度：已知和未知的事物
Hannah L Wallace
Hannah L Wallace
Memory T Cells Subpopulations, COVID-19 Vaccinated and Recovered Subjects: Correspondence [0.03%]
记忆T细胞亚群，COVID-19疫苗接种者和康复者的对比研究
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
Li Zhao,Guanghuan Shen,Jianghan Luo et al.
Li Zhao et al.
Viral infections are ubiquitous, and their prevention and treatment have become a great challenge. Steroids have different biological activities, including antiviral activity, which is related to steroid structural diversity. With the inten...
Investigating the Immunogenic Properties of a Mutagenized NS3/4A-Based HCV Genotype 3a DNA Vaccine [0.03%]
探究基于基因型3a丙型肝炎病毒NS3/4A的突变DNA疫苗的免疫原性属性
Palatip Chutoam,Kanokporn Srisucharitpanit,Uraiwan Intamaso
Palatip Chutoam
Chronic hepatitis C virus (HCV) infection poses a major health risk worldwide, with patients susceptible to liver cirrhosis and hepatocellular carcinoma. This study focuses on the development of effective therapeutic strategies for HCV infe...
Evaluation of an F Protein-Based Recombinant Protein for Immunization Against Respiratory Syncytial Virus [0.03%]
一种基于F蛋白的重组蛋白呼吸合胞病毒疫苗的评估研究
Alicia Hernández-Mercado,Claudia Berenice Barrón-García,Jayline Romo-Amador et al.
Alicia Hernández-Mercado et al.
Respiratory syncytial virus (RSV) is one of the most important etiologies of acute respiratory infections that cause bronchiolitis in children under 5 years of age. Treatments are expensive, no vaccine is available, and this is an important...