Mehmet Can Atayik,Ufuk Çakatay
Mehmet Can Atayik
Next-gen senotherapeutics: AI/ML-driven strategies for aging and age-related disorders [0.03%]
下一代senotherapy：人工智能/机器学习驱动的抗衰老和与年龄相关疾病策略
Prashanth S Javali,Ashish Kumar,Subhajit Sarkar et al.
Prashanth S Javali et al.
Senotherapeutics comprising senolytics and senostats/senomorphs of natural and synthetic origin are powerful pharmacological interventions to combat aging and age-related disorders (ARD): cancer, HIV, diabetes, and neurodegenerative disease...
Polypharmacy as a reason for misinterpreting laboratory results in the elderly [0.03%]
老年人因用药复杂而导致的检验结果误读原因分析
Said İncir,Murat Bolayirli
Said İncir
Today, clinical biochemistry laboratories play increasingly significant roles in diagnosing patients, monitoring treatment responses, and making prognoses. Over the last 50 years, technological advances have greatly impacted laboratory medi...
Şeydanur Turgut,Gülnur Andican
Şeydanur Turgut
Senescent cells progressively accumulate in the endocrine glands and their target tissue during the biological aging process. Senescence leads to hormonal imbalances contributing to various age-related endocrine diseases (AREDs). Cellular s...
Polypharmacy-induced changes in the oral mucosa and jawbone in elderly [0.03%]
老年人多重用药引起的口腔黏膜和下颌骨的变化
Sabahat Zeynep Yey Ozkeskin,Kaan Erisildar,Mehmet Yaltirik
Sabahat Zeynep Yey Ozkeskin
Polypharmacy is increasingly prevalent among the elderly due to the higher incidence of chronic diseases. The oral cavity undergoes age-related changes, including cellular aging and immunosenescence. Thus, susceptibility to oral discomfort ...
Oxygen-ozone adjunct therapy in aging and senescence-related disorders. State of art [0.03%]
氧-臭氧联合疗法在抗衰老及与衰老相关疾病中的应用研究进展
Salvatore Chirumbolo,Giovanni Ricevuti,Marianno Franzini et al.
Salvatore Chirumbolo et al.
Ozone therapy presents as a promising yet controversial approach to anti-aging and health rejuvenation, due to an ongoing and crucially debated need for standardization about protocols, procedures, and dosages. While it offers potential ben...
Anıl Orhan,Süleyman Demiryas
Anıl Orhan
Operating on elderly patients has always been a risky task for surgeons. They are not only frail and susceptible to operative complications, but they also require meticulous preparation before their surgery to secure the optimal result. Unf...
Game changer: Navigating between challenges and hopes in geropharmacology [0.03%]
挑战与希望并存：促进老年药理学研究及药物开发
Qian Chen,Reid Hartman,Lidia Dankiv et al.
Qian Chen et al.
The aging population is expanding rapidly to reshape the social and economic structures. Aging signifies the close to the end of life and threatens health because it features unavoidable compression of body reserve and gradual suppression o...
Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients [0.03%]
老年心血管病患者细胞衰老、多重用药风险及其结局
Tamer Cebe,Fatih Kızılyel
Tamer Cebe
Cardiovascular diseases (CVDs) are closely associated with a chronic inflammatory condition known as senescence and present a considerable challenge when managed alongside age-associated comorbidities. Due to the coexistence of three main p...
Arttatrana Pal
Arttatrana Pal
Cellular senescence (CS) is characterized by stable cell cycle arrest and is resistant to growth-promoting stimuli allied with aging. Cardiac senescent cells (SCs) are highly heterogeneous cells that can regulate the pathophysiology of card...