Unlocking Spondin-1 and Spondin-2 as Ultrasound-Responsive Biomarkers in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: Diagnostic and Therapeutic Perspectives [0.03%]
声控非小细胞肺癌上皮生长因子受体突变型的Spondin-1和Spondin-2生物标志物诊断与治疗潜力的研究
Hai Ou,Feng Jin,Chenyang Wang et al.
Hai Ou et al.
The development of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) remains a huge challenge in treating EGFR-mutant non-small-cell lung cancer (NSCLC). Recent improvements in ultrasound-based cancer bio...
Prognostic Value of Fibrosis-4 in Male Patients with Alcohol-Related Hepatocellular Carcinoma: Implications for Ultrasound-Based Therapeutic Strategies [0.03%]
纤维化4指数对男性酒精性肝癌患者预后的价值：超声引导治疗策略的启示
Chang Guo,Wu-Cai Yang,Bin-Xia Chang et al.
Chang Guo et al.
Background: Hepatocellular carcinoma (HCC) is still the largest cause of cancer-related death globally, with alcohol-related HCC (AR-HCC) being a particularly difficult subtype with poor clinical results. Noninvasive biomarkers, such as the...
Advancing β-Glucan-Based Immunomodulation and Nanotherapeutic Strategies for Cancer Biotherapy [0.03%]
基于β-葡聚糖的免疫调节和癌症生物治疗纳米疗法策略研究进展
Neelakanta Sarvashiva Kiran,Darshini Subramaniam,Chandrashekar Yashaswini et al.
Neelakanta Sarvashiva Kiran et al.
β-glucans are structurally diverse polysaccharides from fungi, yeasts, bacteria, and cereals, exhibiting variable branching and molecular weights that shape their biological activity. Emerging preclinical and clinical evidence highlights t...
[225Ac]Ac-Macropa-PEG4-HEA125 for Targeted α Therapy in Epithelial Cell Adhesion Molecule-Positive Tumors: Conjugation, Radiolabeling, and Efficacy [0.03%]
用于上皮细胞粘附分子阳性肿瘤靶向α治疗的[225Ac]Ac-Macropa-PEG4-HEA125：连接、放射标记和疗效研究
Syed Qaiser Shah,Saba Shirin
Syed Qaiser Shah
Introduction: Epithelial cell adhesion molecule (EpCAM) is overexpressed in a wide range of epithelial malignancies, and thus is a potential target for antibody-based radiotherapy. This work describes the synthesis, labeling, and biological...
Impact of Proactive Nursing on Postoperative Ovarian and Immune Function in Patients Undergoing Ultrasound-Guided Radiofrequency Ablation for Uterine Fibroids [0.03%]
主动护理干预对子宫肌瘤射频消融术患者术后卵巢功能及免疫功能影响的效果观察
Lihong Guo,Li Liu,Xiaodong Zhou et al.
Lihong Guo et al.
Objective: This study analyzed the effectiveness of proactive nursing interventions in patients undergoing ultrasound-guided radiofrequency ablation for uterine fibroids. Materials and Methods: A retrospective analysis included 50 patients ...
Machine Learning Reveals the Association Between Gene Expression and Immune Infiltration in Colorectal Cancer: A Comprehensive Study [0.03%]
机器学习揭示结直肠癌基因表达与免疫浸润关联的全面研究
Ke Zhang,Xin Shen
Ke Zhang
Background: Colorectal cancer (CRC) is a leading cause of cancer mortality globally. The molecular mechanisms of CRC and the accumulating immune cell infiltration in the tumor microenvironment (TME) are essential for enhancing the treatment...
Nanoparticles of Melatonin and Lactoferrin for Improved Drug Delivery and Targeting Tumors in Cancer Treatment [0.03%]
用于改善药物输送和靶向肿瘤的褪黑激素和乳铁蛋白纳米颗粒的癌症治疗
Devansh Shah,Sankha Bhattacharya,Bhupendra G Prajapati et al.
Devansh Shah et al.
This review assesses the promise of nanoparticles containing melatonin and lactoferrin (ML-Lf-NPs) in treating cancer, concentrating on their capacity to improve drug delivery, pinpoint tumors, and optimize therapeutic efficacy. A thorough ...
Preparation and Preliminary Evaluation of a Novel 68Ga-Labeled Linear Peptide PET Probe Targeting Nectin-4 [0.03%]
一种新型镓标记的线性肽PET探针 targeting nectin-4 的制备及初步评价研究
Deng Ke Li,Xue Cen Cao,Chao Mu et al.
Deng Ke Li et al.
Objectives: Nectin-4 has been successfully used as a target for tumor therapy. Although several bicyclic peptides and antibodies, Nectin-4 positron emission tomography (PET) probes, have been reported for tumor imaging and expression detect...
Telomere-Related Gene Risk Model for Prognosis and Immune Landscape in Hepatocellular Carcinoma [0.03%]
肝细胞癌中与端粒相关的基因预后风险模型及免疫图谱
Yuan Gao,Mengjia Huang,Yinan Guan et al.
Yuan Gao et al.
Background: Liver hepatocellular carcinoma (LIHC) is a very aggressive kind of cancer that has a dramatic impact on the quality of life and mean survival of the patient. Consequently, a specific requirement emerges to predict the prognosis ...
The Impact of Gastric Anatomical Subdivisions on the Response to Neoadjuvant Chemotherapy in Gastric Cancer [0.03%]
胃解剖分段对胃癌新辅助化疗疗效影响的研究
Omer Akay,Mert Guler,Husnu Ozan Sevik et al.
Omer Akay et al.
Background: Response to neoadjuvant chemotherapy (NACT) in locally advanced gastric cancer varies. This study compares tumor response to NACT across anatomical locations, considering clinicopathological differences. Materials and Methods: T...