Small Animal Positron Emission Tomography Imaging of a Triple-Negative Breast Cancer Model Using the 68Ga-Labeled pH (Low) Insertion Peptide-Like Peptide YJL-11 [0.03%]
使用68Ga标记的pH(低)插入肽类似物YJL-11对三阴性乳腺癌模型进行小动物正电子发射断层成像学显影研究
Mingming Yu,Fengyu Wu,Yanqin Sun et al.
Mingming Yu et al.
Objectives: To prepare a novel 68Ga-labeled pH (low) insertion peptide-like peptide, YJL-11, and study its ability to be used as a probe for the diagnosis of triple-negative breast cancer (TNBC) via in vivo imaging of tumor-bearing nude mic...
High Expression of Complement 3 Enhances the Efficacy of Neoadjuvant Chemotherapy Prior to Oncoplastic Surgery for HER2-Positive Breast Cancer [0.03%]
补体3高表达可增强HER2阳性乳腺癌保乳术新辅助化疗的疗效
Bo Chen,Lifen Huang,Morui Gui et al.
Bo Chen et al.
Background: Neoadjuvant chemotherapy for breast cancer (BC) improves patient prognosis, but its efficacy is hindered by the disease's high heterogeneity. This study enhances effectiveness of targeted therapy to improve clinical outcomes. Me...
Shafiul Haque,Faraz Ahmad,Vineeta Singh et al.
Shafiul Haque et al.
Aim: This review examined multiple deep learning (DL) methods, including artificial neural networks (ANNs), convolutional neural networks (CNNs), k-nearest neighbors (KNNs), as well as generative adversarial networks (GANs), relying on thei...
An LNM-Associated Gene Signature for Prognostic Prediction and Immune Profiling in Head and Neck Squamous Cell Carcinoma [0.03%]
与LNM相关的基因信号在头颈鳞状细胞癌中的预后预测和免疫分析
Zhenzhen Wang,Zhenhua Wu,Lixin Cheng et al.
Zhenzhen Wang et al.
Lymph node metastasis (LNM) plays a critical role in the prognosis of head and neck squamous cell carcinoma (HNSCC). To enhance prognostic predictions and investigate the molecular interplay between LNM and HNSCC, we developed an LNM-associ...
Comment on "IL-21 and IL-33 May Be Effective Biomarkers to Predict the Efficacy of PD-1 Monoclonal Antibody for Advanced Cholangiocarcinoma" [0.03%]
关于《白介素21和白介素33可能是预测PD-1单克隆抗体治疗胆管癌疗效的有效生物标志物》一文的评论
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
Diagnostic Value of 99mTc-Ubiquicidin Scintigraphy in Differentiating Bacterial from Nonbacterial Pneumonia [0.03%]
99mTc-泛昔啶显像在细菌性和非细菌性肺炎鉴别诊断中的价值
Sepideh Khoshbakht,Saba Zare,Mahdi Khatuni et al.
Sepideh Khoshbakht et al.
Purpose: Differentiating purely viral from bacterial etiologies continues to be a challenging yet key step in the management of community-acquired pneumonia (CAP), further highlighted since the COVID-19 pandemic. This study aims to evaluate...
Aaron T Schatzmann,Tania A Stallons,Rachel Rivera et al.
Aaron T Schatzmann et al.
Background: The cytotoxic effect of 212Pb on microbial growth was examined, using six microorganisms, at clinically relevant time points, to determine the potency of 212Pb as a self-sterilizing agent in radiopharmaceuticals using [212Pb]Pb-...
Heterogeneous Distribution and Absorbed Dose of Radiolabeled Nanoparticles and Colloids in Sentinel Lymph Nodes [0.03%]
放射性标记的纳米粒子和胶体在哨兵淋巴结中的异质分布及吸收剂量
Renata Madru,Erik Larsson,Anders Örbom et al.
Renata Madru et al.
Background: For breast cancer staging, radiolabeled colloids and superparamagnetic iron oxide nanoparticles (SPIONs) are used for sentinel lymph node (SLN) imaging. This study characterized the intranodal activity distribution and absorbed ...
Nab-Paclitaxel Promotes Radiosensitization by Inducing DNA Damage and Inhibiting Macrophage M2 Polarization in Cholangiocarcinoma [0.03%]
Nab-紫杉醇通过诱导DNA损伤和抑制巨噬细胞M2极化促进胆管癌放疗增敏效应
Ningyu Wang,Xiangping Mei,Yang Cao et al.
Ningyu Wang et al.
Background: Nab-paclitaxel effectively inhibits tumor proliferation and modulates macrophage polarization to improve the tumor microenvironment. However, its potential to achieve radiosensitization in cholangiocarcinoma remains to be elucid...