Brain Tumor Classification and Severity Identification Using Deep Convolutional Spiking U-Net Lyrebird Neural Network and Alpha Piecewise Linear-Fuzzy [0.03%]
基于深度卷积脉冲U-网lyrebird神经网络和alpha分段线性模糊的脑肿瘤分类及严重程度识别
Hemanand Chittapragada,Saggurthi Ramesh,Anumula Kalyan Kumar et al.
Hemanand Chittapragada et al.
Purpose: To develop a robust framework that accurately classifies brain tumors and provides an estimation of their severity using an artificial intelligence approach to solve issues related to multimodal MRIs (Magnetic Resonance Imaging), s...
Ultrasound-Guided Microbubble-Assisted Delivery of Radiopharmaceutical Agents for Gastric Tumor Control [0.03%]
超声引导微泡增强胃肿瘤放射药物递送
Changyong Zhao,Qiqi Shen,Lei Qin
Changyong Zhao
Background: Radiopharmaceutical therapy uses drugs with radioactive isotopes for targeted cancer treatment. However, its effectiveness in gastric cancer is often limited by poor tumor penetration, heterogeneous intratumor...
Nanoformulations in Cancer: Focus on Patents and Clinical Trials [0.03%]
纳米制剂在癌症治疗中的应用：专利和临床试验:focus on patents and clinical trials
Tahreen Taj,Joy Das,Utpal Bhui et al.
Tahreen Taj et al.
The transformation of a normal cell state to malignant cell is a multifactorial process, as cancer is a complex network of diseases. There are various types of cancer, each with its own underlying mechanisms and symptoms. The rise in modern...
Analysis and Outlook on the Use of 99mTc-FAPI SPECT/CT in the Diagnosis of Primary and Metastatic Lesions of Cholangiocarcinoma [0.03%]
99mTc-FAPI SPECT/CT在胆管癌原发和转移病灶诊断中应用的分析与展望
Xue Cai,Qingfan Hao
Xue Cai
Introduction: Cholangiocarcinoma (CCA) is an aggressive malignancy characterized by a poor prognosis, where timely diagnosis and accurate staging are critical yet challenging. Conventional imaging techniques often fail to...
Phytochemicals in Oxidative Stress and Cancer Prevention: Emphasis on Seed-Derived Bioactives, Mechanistic Insights, and Nanotechnological Advances [0.03%]
植物化学物质在氧化应激和癌症预防中的作用：侧重于种子衍生生物活性化合物、机制见解和纳米技术进展
Areej,Hafiz Rizwan Sharif,Mian Kamran Sharif et al.
Areej et al.
Phytochemicals are naturally occurring bioactive compounds found in plant seeds. These bioactive substances have attracted considerable attention for their proven potential to modulate oxidative stress and prevent cancer. Seeds are abundant...
Ultrasound-Enhanced CRISPR-Curcumin Nanoparticles for Gene-Modulating Therapy in Metastatic Pulmonary Lesions [0.03%]
用于转移性肺病变的基因调节治疗的超声增强CRISPR-姜黄素纳米颗粒
Xinwen Xu,Xue Yu,Kai Zhang et al.
Xinwen Xu et al.
Background: Curcumin exhibits strong gene-regulatory, epigenetic-modulating, and oncogene-suppressive properties, but its poor aqueous solubility and low intracellular bioavailability limit therapeutic application. Gene-t...
Ultrasound-Potentiated Targeting of GLS1 by an Oridonin Derivative (R13) in Multiple Myeloma: Therapeutic Efficacy and Safety Considerations [0.03%]
高强度聚焦超声增强型奥利隆衍生物（R13）在多发性骨髓瘤中GLS1靶向治疗的疗效及安全性研究
Xi Xu,Yan Zhuang,Yu Zhang et al.
Xi Xu et al.
Objective: To create a structurally optimized oridonin derivative (R13) and study its safety profile, molecular mechanism, and ultrasound-enhanced antitumor activity in multiple myeloma (MM), with an emphasis on glutamine...
18F-FDG PET/CT Combined with Serum Tg and BRAFV600E Mutation for Evaluating Recurrence/Metastasis in RAIR-DTC: Subgroup Analysis and Clinical Decision-Making Value [0.03%]
18F-FDG PET/CT结合血清Tg和BRAFV600E突变评估RAIR-DTC复发/转移的亚组分析及临床决策价值
Ji Liqiu,Zhang Wenwen,Hao Shanhu et al.
Ji Liqiu et al.
Objective: This study evaluated the clinical diagnostic efficacy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for recurrence and/or metastasis in patients with radioactive io...
Ultrasound-Responsive Folate-Chlorogenic Acid Nanocarrier Targeting Mixed Lineage Kinase 1 for Enhanced Wilms Tumor Therapy [0.03%]
叶酸氯ogenic酸纳米载体响应超声针对混合谱系激酶1增强Wilms瘤治疗
Yanjiao Tang,Yunting Meng,Xiaomin Huang et al.
Yanjiao Tang et al.
Background: Wilms tumor (nephroblastoma) is the most frequent malignant tumor of the urinary system in children; however, current treatment choices are restricted due to inadequate drug targeting, systemic toxicity, and m...
Melatonin as an Epigenetic Modulator to Regulate Angiogenesis in Dalton's Lymphoma [0.03%]
褪黑素作为达隆氏淋巴瘤血管生成的表观遗传调控因子
Anju Shrivastava,Rani Kumari
Anju Shrivastava
Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is a promising antitumor agent and antioxidant. The pharmacological dose of melatonin has an oncostatic function by various means, including angiogenesis. Evidences in...