MicroRNA-376a sensitizes cells following DNA damage by downregulating MEPE expression [0.03%]
microRNA-376a通过下调MEPE的表达增强细胞DNA损伤后的敏感性
Jipo Sheng,Wei Luo,Fang Yu et al.
Jipo Sheng et al.
MicroRNAs (miRNAs) are a class of endogenous molecules that post-transcriptionally regulate target gene expression and play an important role in many developmental processes. Matrix extracellular phosphoglycoprotein (MEPE) is related to bon...
Phase I study of a modified regimen of ⁹⁰Yttrium-ibritumomab tiuxetan for relapsed or refractory follicular or transformed CD20+ non-Hodgkin lymphoma [0.03%]
回旋素放射性钇[90Y]依britumomab治疗复发或难治的滤泡性淋巴瘤或转化B细胞非霍奇金淋巴瘤I期临床研究
Christos Vaklavas,Ruby F Meredith,Sui Shen et al.
Christos Vaklavas et al.
Radioimmunotherapy capitalizes on the radiosensitivity of non-Hodgkin lymphoma (NHL) and the targeted nature of monoclonal antibodies. In an attempt to reverse bone marrow infiltration with B-cells and optimize the biodistribution of Yttriu...
Distinct radiosensitivity of lung carcinoma stem-like side population and main population cells [0.03%]
肺癌癌干细胞类似侧群与主要群细胞的放射敏感性差异研究
Pu Xia,Wen-feng Gou,Jin-jin Wang et al.
Pu Xia et al.
Purpose: Lung cancer is a leading cause of cancer death worldwide. Efficacy of radiation therapy on lung cancer is hindered by many factors. Among these, both cancer stem-like side population (SP) and main population (MP)...
Dominant negative epidermal growth factor receptor inhibits growth of human gastric cancer cells by inducing cell cycle arrest and apoptosis [0.03%]
负生长型表皮生长因子受体通过诱导细胞周期停止和凋亡来抑制人类胃癌细胞的生长
Gang Liao,Ziwei Wang,Neng Zhang et al.
Gang Liao et al.
Epidermal growth factor receptor (EGFR) promotes proliferation of cancer cells. Dominant negative EGFR (DNEGFR) can block EGFR signal pathway by competing with endogenous EGFR for ligands. However, whether EGFR is overexpressed in gastric c...
Apoptosis of U937 cells induced by hematoporphyrin monomethyl ether-mediated sonodynamic action [0.03%]
单甲基血卟啉介导的声动力学作用诱导U937细胞凋亡
Xiaomin Su,Pan Wang,Xiaobing Wang et al.
Xiaomin Su et al.
Purpose: The present study aims to investigate apoptosis of U937 cells induced by hematoporphyrin monomethyl ether (HMME)-mediated sonodynamic therapy (SDT). ...
Immunotherapy with cytokine-induced killer cells as an adjuvant treatment for advanced gastric carcinoma: a retrospective study of 165 patients [0.03%]
细胞因子诱导的杀伤细胞免疫疗法作为晚期胃癌综合治疗的辅助治疗：165例患者回顾性分析
Hua Zhao,Yongli Fan,Hui Li et al.
Hua Zhao et al.
Background: Cytokine-induced killer (CIK) cells have demonstrated antitumor effects in vitro and in vivo. The purpose of this study was to evaluate the effect of CIK cell treatment as an adjuvant immunotherapy on the prog...
Yang Wang,Xinwei Zhang,Liang Liu et al.
Yang Wang et al.
MicroRNAs (miRNAs) are a class of endogenous small noncoding regulatory RNAs, which are new regulators of gene expression. They interfere with multiple biological processes involved in tumorigenesis such as cell proliferation, cell cycle, a...
Overcoming paclitaxel resistance in lung cancer cells via dual inhibition of stathmin and Bcl-2 [0.03%]
通过联合抑制stathmin和Bcl-2克服肺癌症细胞中paclitaxel的耐药性
Zheng-Xiang Han,Hong-Mei Wang,Guan Jiang et al.
Zheng-Xiang Han et al.
Lung cancer is the leading cause of death from malignancy in people and over 85% of these patients eventually die from disseminated disease. Paclitaxel (TAX) is widely used as an antimicrotubule agent for the treatment of lung cancer. Unfor...
Glycoprotein 96 and α-fetoprotein cross-linking complexes elicited specific antitumor immunity [0.03%]
糖蛋白96和α-胎盘蛋白交叉连接复合物激发特异性抗肿瘤免疫反应
Xiao-Ping Wang,Qiao-Xia Wang,Huan-Ping Lin et al.
Xiao-Ping Wang et al.
Hepatocellular carcinoma (HCC) is one of the most common malignant gastroenterological cancers over the world. α-fetoprotein (AFP) is an oncofetal protein produced during HCC development that could generate weaker and less reproducible ant...
Can C-arm cone-beam CT detect a micro-embolic effect after TheraSphere radioembolization of neuroendocrine and carcinoid liver metastasis? [0.03%]
C形臂锥形束CT能否检测到TheraSphere选择性内放射治疗神经内分泌和类癌肝转移后的微小栓塞效应？
Olivier Pellerin,MingDe Lin,Nikhil Bhagat et al.
Olivier Pellerin et al.
Rational and objective: Radioembolization with yttrium-90 microspheres is a therapy that is used for hepatic tumors. 20-30 μm microspheres loaded with Y90 are supposedly occluding tumor vessels at the capillary level. Th...