Matthew B Bratton,Jaclyn P Murphy,Jessica C Rivera
Matthew B Bratton
Introduction: Enzymatic debridement has emerged as an alternative method to combat biofilms. Bromelain is an enzyme derived from pineapple stems that has been used in several studies as a method of biofilm dissolution (BD). As a result, res...
Financial and Clinical Toxicity of Empiric Vancomycin for Intra-Abdominal Infections: A Cohort Study [0.03%]
经验性使用万古霉素治疗腹腔内感染的经济和临床毒性：队列研究
Laura M Ebbitt,Jeremy D VanHoose,Samantha Manci et al.
Laura M Ebbitt et al.
Background: Vancomycin for intra-abdominal infections (IAI) should be reserved for healthcare-acquired infections, history of multiple interventions, or methicillin-resistant Staphylococcus aureus (MRSA). The MRSA incidence is low; however,...
Nomogram for Predicting Post-Operative Pulmonary Infection in Patients with Traumatic Intra-Cranial Hematoma [0.03%]
颅脑损伤患者术后肺部感染预测列线图
Jian-Rong Yu,Hai Hu,Hong Luo et al.
Jian-Rong Yu et al.
Background: This study sought to determine key risk factors for post-operative pulmonary infections (PPIs) in traumatic intra-cranial hematoma (TICH) patients and to develop a nomogram for evaluating infection risk. Methods: A retrospective...
Negative Nasal Methicillin-Resistant Staphylococcus aureus (MRSA) Polymerase Chain Reaction Rules Out Future MRSA Infections in Severely Injured Trauma Patients [0.03%]
伤员鼻腔甲氧西林耐药金黄色葡萄球菌聚合酶链式反应阴性预示未来不会发生该病感染
Gregory R Stettler,Kaely Miller,Kristen A Rebo et al.
Gregory R Stettler et al.
Introduction: Studies have shown that methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR) swabs aid in de-escalating and decreasing the duration of antibiotic use in respiratory infections. However, the utilit...
Prevention of Surgical Site Infection after Spine Operation with Care Bundle [0.03%]
脊柱手术后采用护理包预防手术部位感染
Masakazu Toi,Keishi Maruo,Fumihiro Arizumi et al.
Masakazu Toi et al.
Background: A Care Bundle is proposed to prevent surgical site infections (SSIs). This study investigated SSI incidence and risk factors at our hospital, developed an SSI prevention Care Bundle, and tested its efficacy. Methods: A retrospec...
Surgical Infection Society Multi-Center Observational Study: Empiric Anti-Fungal Coverage after Non-Colonic Gastrointestinal Perforation [0.03%]
胃肠道穿孔术后经验性抗真菌治疗的多中心观察研究
Andrea M Gochi,Wardah Rafaqat,Vahe Panossian et al.
Andrea M Gochi et al.
Background: Empiric anti-fungals are frequently administered in patients with non-colonic gastrointestinal (GI) perforations, but there is limited evidence of their benefit. We hypothesized that empiric anti-fungals would offer no clinical ...
Antimicrobial Stewardship Impact on the Treatment of Intra-abdominal Infections in the Surgical Intensive Care Unit [0.03%]
抗菌药物管理对外科重症监护室腹腔内感染治疗的影响
Meghan E Peterson,Jade Flynn,Michael C Smith et al.
Meghan E Peterson et al.
Background: Broad-spectrum antibiotic agents are utilized for complicated intra-abdominal infection (cIAI); however, the need for empiric methicillin-resistant Staphylococcus aureus (MRSA) coverage is not clear as the incidence of MRSA cIAI...
Surgical Site Infections Following Pelvic Sarcoma Reconstruction with 3D-Printed Implants: Current Concepts and Future Directions [0.03%]
三维打印假体骨盆肉瘤重建术后手术部位感染的现状及展望
Sadegh Saberi,Hamed Naghizadeh,Khalil Kargar Shooroki et al.
Sadegh Saberi et al.
Introduction: Surgical site infections (SSIs) are a major complication following pelvic sarcoma reconstruction using 3D-printed implants. Despite advances in anatomical matching and biomechanics, infection rates remain significantly higher ...
Persistent Post-Recovery Hyperinflammation of Necrotizing Enterocolitis Is Ameliorated by 5-ASA Treatment [0.03%]
5-ASA治疗可缓解坏死性小肠结肠炎后的持续过度炎症反应
Katherine Brooke Snyder,Cody Dalton,Grant Gershner et al.
Katherine Brooke Snyder et al.
Background: Necrotizing enterocolitis (NEC) is the leading gastrointestinal cause of death of premature neonates. We have previously shown that this hyperinflammatory state persists even post-recovery. We hypothesize that recovered patients...
Triple Versus Double Antibiotic Therapy in Children Undergoing Laparoscopic Appendicectomy for Complicated Appendicitis: A Case-Control Study [0.03%]
复杂性阑尾炎患儿腹腔镜阑尾切除术围手术期三联与双联抗生素治疗的疗效分析：病例对照研究
Kai-Zheong Lim,Ramesh M Nataraja,Maurizio Pacilli
Kai-Zheong Lim
Background and Objectives: Historically, a triple-antibiotic (TA) regimen (ampicillin, gentamicin, metronidazole) has been used for children with complicated appendicitis (CA) at our institution. We implemented a double-antibiotic (DA) regi...