Sushree Subhadra Acharya,Subhasmita Bhal,Biswajit Das et al.
Sushree Subhadra Acharya et al.
Cancer vaccines have become a promising approach in the fight against cancer, harnessing the remarkable capability of the human immune system to recognize and eliminate cancer cells. These vaccines are specifically engineered to activate th...
Progress in modifying and delivering mRNA therapies for cancer immunotherapy [0.03%]
用于癌症免疫治疗的mRNA疗法的修饰和传递方面的新进展
Karan Goel,Isha Chawla,Garima et al.
Karan Goel et al.
Advancements in mRNA-based therapeutics have greatly enhanced cancer immunotherapy by using the immune system to specifically target and eradicate cancer cells. There has been notable advancement in tailoring and administering mRNA to treat...
Arun Kumar Singh,Karan Goel,Meenakshi Dhanawat
Arun Kumar Singh
for delivery of plasmid DNA and mRNA transform biology and medicine, offering powerful tools for gene therapy, vaccine development, cancer immunotherapy, and regenerative medicine. Plasmid DNA provides a relatively stable and sustained expr...
Kashish Wilson,Garima,Meenakshi Dhanawat
Kashish Wilson
The number of immuno-oncology medication approvals in current years has increased, indicating the immense potential of cancer immunotherapy. Nucleic acid therapy has advanced significantly in the interim. The diverse capabilities of nucleic...
Therapeutic mRNAs for cancer immunotherapy: From structure to delivery [0.03%]
癌症免疫疗法的治疗性 mRNA：从结构到递送
Monika Vishwakarma,Wasim Akram,Tanweer Haider
Monika Vishwakarma
mRNA carries genetic information and is used for the synthesis of proteins, fragments of proteins, and peptides in the scope of biotechnology and medicine. Once introduced into cells, this mRNA gets translated into a corresponding protein w...
Pranav Kumar Prabhakar,Tarun Kumar Upadhyay,Sanjeev Kumar Sahu
Pranav Kumar Prabhakar
Malignant melanoma is one of the most aggressive forms of cancer and a leading cause of death from skin tumors. With the rising incidence of melanoma diagnoses, there is an urgent need to develop effective treatments. Among the most modern ...
DNA and mRNA vaccines: Significant therapeutic approach against cancer management [0.03%]
DNA和mRNA疫苗：癌症治疗的重要方法
Aniruddha Sen,Vijay Singh,Sumel Ashique et al.
Aniruddha Sen et al.
Cancer's complex nature and personal variety make it among the toughest cancers to conquer. Innovative treatment strategies can be achieved through new biotechnology developments. DNA and mRNA vaccinations deliver an opportunity to take a n...
System-level integrative omics analysis to identify the virus-host immunometabolic footprint during infection [0.03%]
系统水平的集成组学分析揭示感染过程中的病毒-宿主免疫代谢表征
Anoop Ambikan,Sara Svensson Akusjärvi,Maike Sperk et al.
Anoop Ambikan et al.
The emergence and re-emergence of infectious diseases present significant global health threats. Understanding their pathogenesis is crucial for developing diagnostics, therapeutics, and preventive strategies. System-level integrative omics...
Matthew McCullen,Eugene Oltz
Matthew McCullen
The immune system requires a complex network of specialized cell types to defend against a range of threats. The specific roles and destinies of these cell types are enforced by a constellation of gene regulatory programs, which are orchest...
Unravelling the contribution of lymph node fibroblasts to vaccine responses [0.03%]
解构淋巴结成纤维细胞对疫苗反应的贡献
Isabella Cinti,Kassandra Vezyrgianni,Alice E Denton
Isabella Cinti
Vaccination is one of the most effective medical interventions, saving millions of lives and reducing the morbidity of infections across the lifespan, from infancy to older age. The generation of plasma cells and memory B cells that produce...