Marina Mayer,Eliana Franco Taveras,Elvira Mass
Marina Mayer
Macrophages are essential immune cells that arise early during embryogenesis and persist as tissue-resident cells into adulthood. This chapter explores macrophage development, focusing on their roles in the nervous system. We describe their...
Neuroimmunology beyond the CNS: Nerve-macrophage interactions in peripheral tissues [0.03%]
超越中枢神经系统的神经免疫学：外周组织中的神经-巨噬细胞相互作用
Erin Watson,Elaine Emmerson
Erin Watson
Macrophages are now recognised to be highly heterogeneous, with diverse ontogenies, anatomical locations and characteristics, all of which inform their function. Nerve-associated macrophage subpopulations have been found to exist across tis...
Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination [0.03%]
γδ T细胞调节体液免疫：疫苗接种的潜在佐剂策略
Kirsty Emery,Matthias Eberl
Kirsty Emery
Vaccination is arguably the most effective intervention in reducing the impact of infectious diseases. However, many vaccines provide only partial or transient protection, prompting the need for more effective solutions based on our growing...
Rebecca A Drummond
Rebecca A Drummond
Fungal infections are increasingly recognised as a major threat to global human health, with several million preventable deaths each year now attributable to fungal diseases. Climate change, global pandemics and increased use of antibiotics...
Rakesh Pahwa,Gulshan Sharma,Rohil Panwar et al.
Rakesh Pahwa et al.
The emergence of mRNA-based cancer immunotherapy has transformed the avenue of cancer treatment, offering an innovative strategy that leverages the body's immune system to identify and eradicate tumor cells selectively. Effective delivery o...
Gyati Shilakari Asthana,Saptarshee Bhattacharjee,Jitendra Kumar et al.
Gyati Shilakari Asthana et al.
Lipid nanoparticles (LNPs) to deliver messenger RNA (mRNA) have emerged as a transformative strategy in cancer immunotherapy. This chapter explores the pivotal role of LNPs in enabling the efficient and targeted delivery of mRNA for cancer ...
Recent progress, challenges (stability and in vivo distribution), and opportunities of DNA & mRNA vaccine in cancer immunotherapy [0.03%]
DNA和mRNA疫苗在肿瘤免疫治疗中的最新进展、挑战（稳定性及体内分布）与机遇
Monika Kaushik,Prathap Madeswaraguptha,Murugesan Vanangamudi et al.
Monika Kaushik et al.
Cancer immunotherapy recently has emerged as a revolutionary method in oncology. It takes the help of the body's immune system in fighting against tumor cells. Amongst the various approaches, DNA and mRNA vaccines are novel modalities with ...
Revolutionizing cancer treatment: Exploring novel immunotherapeutics, checkpoints, bispecifics, and vaccines in development [0.03%]
癌症治疗革新：探索新型免疫疗法、检查点、双特异性抗体和在研疫苗
Anas Islam,Vijay Singh,Pooja S Murkute et al.
Anas Islam et al.
This chapter focuses on the groundbreaking advances in the treatment of cancer via the development of innovative immunotherapies, which include immune checkpoint inhibitors, bispecific antibodies, and cancer vaccines. The chapter begins wit...
Personalized precision: Revolutionizing cancer treatment with mRNA-based vaccines in melanoma therapy [0.03%]
个性化精准治疗：利用基于mRNA的疫苗革新黑色素瘤治疗
Krishnendu Adhikary,Abhik Paul,Ayush Madan et al.
Krishnendu Adhikary et al.
Biological and societal issues are involved when we refer to a condition as cancer, which connotes loss, complexity, and uncertainty. In recent decades, the number of melanomas has climbed. Cancer treatment vaccines have induced immune resp...
Pritha Roy Choudhury,Mohona Chakravarti,Saptak Banerjee et al.
Pritha Roy Choudhury et al.
Lately, the urgency of precision medicine in cancer care through immunotherapy has reformed the arena of oncology. Although immunomodulatory therapeutics in cancer have been preliminarily concentrated on T-cells, emerging evidences have sug...