Sophie Kogut,Mónica Padilla-Gálvez,Daniel Blanco-Melo
Sophie Kogut
Human endogenous retroviruses (HERVs) provide a direct record of the millions of years of co-evolution between humans and viruses. Yet, due to their repetitive nature and former reputation as "junk DNA," a full characterization of the funct...
Viral threats to pregnancy: Global health risks in the era of pandemics [0.03%]
妊娠期病毒威胁： pandemic时代的全球健康风险
Guilherme M Nobrega,Amit Garg,Jean K Lim
Guilherme M Nobrega
Pregnancy represents a uniquely vulnerable period during which viral infections can exert profound effects on maternal health, placental function, and fetal development. Over the past 30 years, emerging and re-emerging viruses, including fl...
Transforming crop protection: The role of RNAi in mitigating barley yellow dwarf virus and aphid infestation in cereal crops [0.03%]
作物保护的变革：RNAi在缓解麦类作物黄矮病病毒和蚜虫危害中的作用
Nora Derbal,Narelle Manzie,Karl E Robinson
Nora Derbal
RNA interference (RNAi) is emerging as a powerful technology to potentially protect wheat and barley crops from plant viruses such as Luteovirus pashordei, historicaly known as barley yellow dwarf virus (BYDV), and insect/vector pest infest...
Natasa Mehle,Adrian Fox,Antonio Tiberini et al.
Natasa Mehle et al.
The vertical transmission of tomato viruses through seeds and pollen is a significant yet often overlooked pathway for the persistence and global spread of these pathogens. This review provides a comprehensive synthesis of current knowledge...
Lucía García Ordóñez,Cristina Sáez,Israel Pagán
Lucía García Ordóñez
Plant virus emergence is a major threat for agricultural production and for the preservation of biodiversity in wild ecosystems. This process is determined by genetic and ecological factors and, among the latter, one of the most important i...
The significance of studying high-consequence pathogens in their natural reservoirs [0.03%]
研究高致病性病原体自然宿主的意义
Levi Klassen,Jérémie Prévost,David Safronetz
Levi Klassen
Concern over spillover events caused by high-consequence pathogens has grown in recent years due to the increased occurrence of such events, and because the COVID-19 pandemic demonstrated how severe the consequences of spillover events can ...
Swine model of Bundibugyo and Reston virus infection reveals a robust immune response following the infection: A multi-tissue immune profiling study [0.03%]
布ン迪博约病毒和Reston病毒感染的猪模型揭示了感染后的强烈免疫反应：多组织免疫谱分析研究
Ji-Young V Kim,Charles E Lewis,Mathieu Pinette et al.
Ji-Young V Kim et al.
Domestic pigs are a vital component of the global food supply, with a population nearing 780 million worldwide, making them one of the most commonly raised livestock. As pig production intensifies, the associated practices and environmental...
More similar than different: A comparison of human and veterinary maximum containment facilities [0.03%]
殊途同归：人用和兽用生物安全四级实验室比较研究
Sandra Diederich,Michael Eschbaumer
Sandra Diederich
Human maximum containment facilities-also known as biosafety level 4 (BSL-4) laboratories-for zoonotic viruses such as Ebola virus or Nipah virus and veterinary maximum containment (BSL-4vet) facilities, e.g. for foot-and-mouth disease viru...
Transcriptional signatures of Ebola and Marburg virus infection in a bat-immune-system (BIS) mouse model [0.03%]
埃博拉病毒和马堡病毒感染的 transcriptional 签名：蝙蝠免疫系统小鼠模型研究
Dániel Cadar,Balázs Horváth,Melanie Rissman et al.
Dániel Cadar et al.
Bats are the reservoir hosts for a diverse range of viruses, including some that are highly pathogenic to humans, yet they generally harbor these pathogens without showing symptoms. This unique tolerance to viral infection makes them a crit...
Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection [0.03%]
黏膜苏丹病毒感染会导致先前感染Lloviu病毒的实验动物致死性的疾病而不会产生交叉保护作用
Kyle L O&#x;Donnell,Paige Fletcher,Hanna Anhalt et al.
Kyle L O&#x;Donnell et al.
Sudan virus (SUDV) causes highly lethal outbreaks of hemorrhagic disease throughout Africa, but there has yet to be an approved vaccine or therapeutic to combat this public health threat. The most common route of natural exposure to filovir...