Robert S Brown Jr
Robert S Brown Jr
Liver Failure from Alcohol Takes on Several Forms: Decompensated Cirrhosis, Acute-on-Chronic Liver Failure, and Alcohol-Related Hepatitis [0.03%]
酒精性肝病导致的肝脏衰竭：失代偿期肝硬化、慢性肝功能衰竭急性发作和酒精性肝炎
Gene Y Im
Gene Y Im
Liver failure from alcohol can take on several forms, including decompensated alcohol-related cirrhosis (AC), acute-on-chronic liver failure (ACLF), and alcohol-related hepatitis (AH). While the definitions of decompensated AC and AH are we...
Stephanie Rutledge,Robert S Brown Jr
Stephanie Rutledge
Severe alcohol-associated hepatitis (AH) is associated with high mortality and is rising in incidence but there are limited treatment options. Therapies being studied for AH include those targeting systemic cytokine-mediated inflammation, h...
Howard D Lee,Brian P Lee
Howard D Lee
Alcohol-related hepatitis (AH) is the most acute and severe manifestation of alcohol-related liver disease. AH represents a spectrum of disease and portends poor prognosis with severe disease. Severe AH can have up to a 70% mortality at 6 m...
Haripriya Maddur,Steven Flamm
Haripriya Maddur
Alcohol-related liver injury is complex and remains poorly understood. Research to date has pinpointed the role of oxidative stress, hepatic inflammation, and derangements in lipid metabolism as drivers of disease pathogenesis. More recent ...
Alcohol-Related Liver Disease: Spectrum of Disease, Natural History, and Outcomes [0.03%]
酒精性肝病：疾病谱、自然史和预后
Jessica A Musto,John P Rice
Jessica A Musto
Alcohol-related liver disease (ALD) is a common cause of liver-related mortality and a leading indication for transplantation. On histopathology, bland steatosis is generally nonprogressive while steatohepatitis can lead to progressive fibr...
Post Liver Transplant Management and Outcomes in Alcohol-Related Liver Disease [0.03%]
酒精性肝病患者的术后管理及转归研究
Mohammed Abusuliman,Yara Dababneh,Gerald Scott Winder et al.
Mohammed Abusuliman et al.
This narrative review explores post liver transplant (LT) management in patients with alcohol-related liver disease (ALD), emphasizing the challenges and strategies for preventing alcohol relapse. It discusses evolving practices like early ...
Vladislav Fomin,Stephanie Rutledge,Robert S Brown Jr
Vladislav Fomin
The psychosocial evaluation for liver transplant candidates with alcohol-associated liver disease (ALD) has evolved dramatically. The evaluation process has evolved from a stringent 6-month abstinence rule to robust, evidence-based assessme...
Larissa Lushniak,Ashley Jowell,Stephanie Garbarino et al.
Larissa Lushniak et al.
Alcohol-associated liver disease has always been a significant health issue. During the coronavirus disease 2019 pandemic, there were higher rates of alcohol consumption, and these higher rates have persisted after pandemic. Given the signi...
Mashal Khan,Sahil Anand,Akhil Shenoy
Mashal Khan
This review article focuses on the management of alcohol use disorder (AUD) in patients with comorbid alcohol-associated liver disease (ALD). We highlight the importance of different screening tools for AUD in addition to the role of FDA an...