Compliance of Glaucoma Patients to Ocular Hypotensive Medications Among the Saudi Population [0.03%]
沙斯人群中青光眼患者的眼内压抑制药物依从性研究
Essam A Osman,Bader Ahmed Mousa Alqarni,Sara Salem Humaid AlHasani et al.
Essam A Osman et al.
Purpose: To evaluate the compliance of glaucoma patients to medical treatment and its impact on the intraocular pressure (IOP) and to verify the associated risk factors for noncompliance. ...
Changes in Pupil Size Following Panretinal and Focal/Grid Retinal Photocoagulation: Automatic Infrared Pupillometry Study [0.03%]
全视网膜和局部/网格视网膜光凝后瞳孔大小变化的自动红外瞳距测量研究
Ihsan Yilmaz,Miray Faiz,Basak Saracoglu et al.
Ihsan Yilmaz et al.
Purpose: To evaluate possible changes in pupil size subsequent to panretinal and focal/grid laser photocoagulation. Methods: Sixty-four...
Miguel Cuchacovich,Federica Solanes,Claudio Perez et al.
Miguel Cuchacovich et al.
Purpose: To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. ...
The In Vitro Evaluation of Tigecycline and the In Vivo Evaluation of RPX-978 (0.5% Tigecycline) as an Ocular Antibiotic [0.03%]
特利考奇的体外评价和RPX-978（0.5%特利考奇）作为眼科抗生素的体内评价
Eric G Romanowski,Tyler A Kowalski,Katherine E O&#x;Connor et al.
Eric G Romanowski et al.
Purpose: The goals of the current study were to determine the in vitro antibacterial activity of tigecycline against multiple clinically relevant ocular pathogens and to evaluate the in vivo ocular tolerability and effica...
Shriji Patel,Joshua M Barnett,Stephen J Kim
Shriji Patel
Purpose: Polyethylene glycol (PEG)-400 is a clear, colorless viscous liquid that readily dissolves many hydrophobic drugs. It is a widely used commercial solvent and vehicle for many pharmaceutical and cosmetic products. ...
Immediate Intraocular Pressure Changes Following Intravitreal Dexamethasone Implant [0.03%]
注射玻璃体内倍他米松缓释植入剂后眼压的即刻变化
Neşe Alagöz,Cengiz Alagöz,Ihsan Yılmaz et al.
Neşe Alagöz et al.
Purpose: To evaluate the immediate intraocular pressure (IOP) changes following intravitreal dexamethasone implantation. Methods: Thirt...
Species Differences in the Geometry of the Anterior Segment Differentially Affect Anterior Chamber Cell Scoring Systems in Laboratory Animals [0.03%]
实验室动物眼眼前段结构几何差异影响眼前房细胞评分系统评估效力
Sara M Thomasy,J Seth Eaton,Matthew J Timberlake et al.
Sara M Thomasy et al.
Purpose: To determine the impact of anterior segment geometry on ocular scoring systems quantifying anterior chamber (AC) cells in humans and 7 common laboratory species. ...
How Much Nonclinical Safety Data Are Required for a Clinical Study in Ophthalmology? [0.03%]
眼科临床研究需要多少非临床安全数据？
Gary D Novack,Elizabeth D Moyer
Gary D Novack
Planning the nonclinical development program for an ophthalmic product requires first an understanding of how the drug will be used in the clinic-topical, injected, relatively short duration of testing, chronic testing, and what is already ...
Ocular Adverse Events Associated with Antibody-Drug Conjugates in Human Clinical Trials [0.03%]
抗体药物偶联物的人体临床试验相关眼部不良事件
Joshua Seth Eaton,Paul E Miller,Mark J Mannis et al.
Joshua Seth Eaton et al.
This article reviews ocular adverse events (AEs) reported in association with administration of antibody-drug conjugates (ADCs) in human clinical trials. References reporting ocular toxicity or AEs associated with ADCs were collected using ...