Gary D Novack
Gary D Novack
Integrated Bioinformatics and Explainable Machine Learning Analyses Reveal Mesenchymal Stem Cell Exosome-Related Biomarkers for Diabetic Retinopathy [0.03%]
整合生物信息学和可解释的机器学习分析发现用于糖尿病视网膜病变的间充质干细胞外泌体相关生物标志物
Liu Zheng,Jiaojiao Jiang,Jinqing Li et al.
Liu Zheng et al.
Purpose: This study aims to identify potential biomarkers for diabetic retinopathy (DR) by focusing on genes associated with mesenchymal stem cell-derived exosomes (MSCs-Exo). ...
Real-World Anatomical Outcomes of Suprachoroidal Triamcinolone Acetonide Injections in a Large Retinal Practice over a 4-Year Period [0.03%]
超乳注药在大型视网膜疾病诊疗中心4年间的临床解剖效果观察
Chase W Miller,Casey A Scroggins,Shannon L Wuller et al.
Chase W Miller et al.
Purpose: To evaluate the clinical role, durability, anatomical response, and safety for suprachoroidal triamcinolone acetonide (SCTA) (Xipere) in routine clinical practice. ...
Soluble Guanylate Cyclase Modulators in Glaucoma and Ocular Fibrosis: Mechanisms, Translational Evidence, and Therapeutic Challenges [0.03%]
可溶性鸟苷酸环化酶调节剂在青光眼和眼纤维化中的机制、转化证据及治疗挑战
M S A Mohamed
M S A Mohamed
The purpose is to review the role of the nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) signaling pathway in glaucoma, focusing on trabecular meshwork (TM) function, aqueous humor outflow, intraocula...
Geroprotective Agents, Including Glucagon-Like Peptide-1 Receptor Agonists, for Ocular Health [0.03%]
具有GLP-1受体激动剂的抗衰老药物用于眼部健康
Alan Nguyen,Aretha Y Zhu,Albert S Khouri
Alan Nguyen
Aging has long been implicated in the onset and progression of major retinal diseases, including age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinal vein occlusion (RVO). Glaucoma is likewise increasingly recogniz...
Comparative Efficacy and Safety of Topical Bepotastine Besilate 1.5% Versus Sodium Cromoglycate 4% in Chronic Allergic Conjunctivitis: A Prospective Study [0.03%]
贝帕斯特 besilate 治疗慢性过敏性结膜炎的疗效及安全性与色甘酸钠相比：前瞻性研究
Mayank Jhanwar,Sumit Goyal,Ajay Nathan
Mayank Jhanwar
Purpose: To compare the efficacy, safety, and patient satisfaction of bepotastine besilate 1.5% versus sodium cromoglycate 4% eye drops in the management of chronic allergic conjunctivitis. ...
Alexandria C Hofmann,Nishant R Sinha,Abigail Hurtado et al.
Alexandria C Hofmann et al.
Purpose: Corneal inflammation is a common clinical condition that contributes to loss of corneal transparency. This study evaluated the potential of pirfenidone (PFD), an FDA-approved drug, to inhibit inflammation in the ...
Gary D Novack
Gary D Novack
Systemic Infliximab Is Efficacious for the Control of Pediatric Uveitis Including in Adalimumab-Refractory Patients [0.03%]
系统性英夫利西单抗对儿童期葡萄膜炎疗效显著，包括对于阿达木单抗治疗无效的患者同样有效
Ian R Reekie,Laura Ramm,Eslam Al-Abadi et al.
Ian R Reekie et al.
Introduction: This retrospective study aims to assess the efficacy of infliximab by intravenous infusion in treating pediatric non-infectious uveitis, including as a second-line anti-tumor necrosis factor (TNF) for patients with insufficien...
Integrative Mechanistic Insights into Benzalkonium Chloride-Induced Cytotoxicity in Human Corneal Epithelial Cells [0.03%]
苯扎氯铵诱发人角膜上皮细胞毒性的整合机制研究
Farzaneh Motafeghi,Ehsan Ghassemi Barghi,Jafar Gholami Gharab et al.
Farzaneh Motafeghi et al.
This study aimed to provide integrative mechanistic insights into benzalkonium chloride (BAK)-induced cytotoxicity in human corneal epithelial (HCE-T) cells, with a particular focus on the crosstalk between oxidative stress, DNA damage, fer...