Brian S McKay,Stephen G Schwartz
Brian S McKay
Topical Application of Naltrexone to the Ocular Surface of Healthy Volunteers: A Tolerability Study [0.03%]
用于健康志愿者结膜下给药的纳曲酮耐受性研究
David Liang,Joseph W Sassani,Patricia J McLaughlin et al.
David Liang et al.
Purpose: A short-term, randomized double-masked study was conducted to test the tolerability of topical application of naltrexone to the corneal surface. ...
RETRACTED: Azithromycin 1.5% Ophthalmic Solution for Blepharitis Treatment: Comparison of 14- Versus 30-Day Treatment [0.03%]
临床试验撤回：1.5％阿奇霉素眼科溶液治疗睑缘炎：14天与30天疗程的比较
Yesim Altay,Gulizar Demirok,Ozgur Balta et al.
Yesim Altay et al.
The online-ahead-of-print published article, "Azithromycin 1.5% Ophthalmic Solution for Blepharitis Treatment: Comparison of 14- Versus 30-Day Treatment," by Altay Yesim, Demirok Gulizar, Balta Ozgur, and Bolu Hulya (DOI: 10.1089/jop.2015.0...
Ocular Applications of Dipyridamole: A Review of Indications and Routes of Administration [0.03%]
双嘧达莫在眼科应用中的适应证和给药方式综述
Moshe Rogosnitzky,Itzhak Isakov,Wjatschesslaw Wlassoff et al.
Moshe Rogosnitzky et al.
Dipyridamole was introduced decades ago as a treatment for angina, subsequently found to inhibit platelet aggregation. It is most commonly used, and approved for use in thromboembolism prevention, following surgery. Some of its recognized e...
Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds [0.03%]
多孔聚乳酸-羟基乙酸盐支架上诱导多能干细胞向神经视网膜前体细胞的分化
Kristan S Worthington,Luke A Wiley,C Allan Guymon et al.
Kristan S Worthington et al.
Purpose: Cell replacement therapy for the treatment of retinal degeneration is an increasingly feasible approach, but one that still requires optimization of the transplantation strategy. To this end, various polymer subs...
Eric M George,Fakhri Mahdi,Omar C Logue et al.
Eric M George et al.
Purpose: Elastin-like polypeptide (ELP) is a bioengineered protein widely applied as a drug carrier due to its biocompatibility and amenability to modification with cell-penetrating peptides (CPPs) and therapeutic agents....
Venkata Kashyap Yellepeddi,Srinath Palakurthi
Venkata Kashyap Yellepeddi
Topical ocular drug delivery has been considered to be an ideal route of administration for treatment of ocular diseases related to the anterior segment of the eye. However, topical ocular delivery is a challenging task because of barriers ...
Immediate Effects of 3% Diquafosol and 0.1% Hyaluronic Acid Ophthalmic Solution on Tear Break-Up Time in Normal Human Eyes [0.03%]
3%滴夸福索和0.1%透明质酸钠眼用溶液对正常人眼睛泪膜破裂时间的即刻影响
Ki Tae Nam,So Min Ahn,Youngsub Eom et al.
Ki Tae Nam et al.
Purpose: The purpose of this study was to evaluate the immediate effect of 3% diquafosol ophthalmic solution on tear break-up time (TBUT) in normal human eyes, and to compare it with that of saline and 0.1% hyaluronate op...
Brimonidine Can Prevent In Vitro Hydroquinone Damage on Retinal Pigment Epithelium Cells and Retinal Müller Cells [0.03%]
溴莫尼定可以防止对羟基苯醌所致视网膜色素上皮细胞和视网膜穆勒细胞的损伤
Claudio Ramírez,Javier Cáceres-del-Carpio,Justin Chu et al.
Claudio Ramírez et al.
Purpose: Brimonidine is a selective alpha-2 adrenergic agonist used to reduce intraocular pressure and it has been shown to have some neuroprotective effects. Hydroquinone (HQ) is a toxicant present in cigarette smoke, an...
Nonresponders to Prostaglandin Analogs Among Normal-Tension Glaucoma Patients [0.03%]
低血压正常眼压性青光眼患者的前列腺素类似物非响应者
Kenji Inoue,Akira Setogawa,Goji Tomita
Kenji Inoue
Purpose: To investigate patients whose intraocular pressure (IOP) did not decrease after treatment using a prostaglandin analog (nonresponders). Methods: ...