Immunosuppressive Treatment Can Alter Visual Performance in the Royal College of Surgeons Rat [0.03%]
免疫抑制治疗可改变罗斯理查森大鼠的视功能
Ann E Cooper,Jang-Hyeon Cho,Steven Menges et al.
Ann E Cooper et al.
Purpose: Immunosuppression is frequently employed to enhance survival of xenografted human cells as part of translational proof-of-concept studies. However, the potential effects of this treatment are easily overlooked. ...
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma [0.03%]
trabodenoson眼科给药的剂量递增研究：两次每日给药持续两周和四周治疗开角型青光眼或高眼压症的安全性，耐受性和药代动力学特性
Jonathan S Myers,Kenneth N Sall,Harvey DuBiner et al.
Jonathan S Myers et al.
Purpose: To evaluate the safety and ocular hypotensive efficacy of 4 trabodenoson doses administered twice daily over 14 or 28 days in subjects with ocular hypertension or primary open-angle glaucoma (POAG). ...
Long-Term Outcomes of Anti-Vascular Endothelial Growth Factor Therapy for Polypoidal Choroidal Vasculopathy [0.03%]
抗血管内皮生长因子治疗息肉状脉络膜血管病变的长期疗效分析
Young Suk Chang,Jae Hui Kim,Kyung Min Kim et al.
Young Suk Chang et al.
Purpose: To investigate a clinical outcome after more than 4 years for polypoidal choroidal vasculopathy (PCV) treated with anti-vascular endothelial growth factor (VEGF) therapy and to investigate the factors predictive ...
Dexamethasone Implant for the Treatment of Type 1 Idiopathic Macular Telangiectasia [0.03%]
曲安奈德植入物治疗特发性黄斑 telangiectasia 1型的疗效观察
Gürkan Erdoğan,Tuğba Aydoğan,Cihan Ünlü et al.
Gürkan Erdoğan et al.
Purpose: To report our results of 4 patients about the efficacy and safety of intravitreal dexamethasone implant for type 1 idiopathic macular telangiectasia (IMT). ...
Successful Implementation of a Program for Increasing Donor Eyes for Research: The Duke-Miracles In Sight Program [0.03%]
一个增加研究用捐献眼角膜的项目的成功实施——杜克-Miracles In Sight项目经验
Andrew M Williams,Kristin M Perkumas,Isaac Perry et al.
Andrew M Williams et al.
Purpose: Although essential for development of ocular therapeutics, the quality and quantity of human donor eyes for research have been on the decline. To streamline procurement protocols, provide better medical documenta...
W Michael Dismuke,Darryl R Overby,Mortimer M Civan et al.
W Michael Dismuke et al.
Eye-Directed Overpressure Airwave-Induced Trauma Causes Lasting Damage to the Anterior and Posterior Globe: A Model for Testing Cell-Based Therapies [0.03%]
眼定向超压气浪伤致眼前、后节持续性损伤：细胞治疗研究的模型动物
Courtney Bricker-Anthony,Jessica Hines-Beard,Tonia S Rex
Courtney Bricker-Anthony
Purpose: Characterization of the response of the Balb/c mouse to an eye-directed overpressure airwave, with the hypothesis that this mouse strain and model is useful for testing potential therapeutics for the treatment of...
Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig [0.03%]
蓝莓提取物对 Guinea Pig 眼镜屈光不正发展的影响
Hong-Wei Deng,Yuan Tian,Xiao-Juan Zhou et al.
Hong-Wei Deng et al.
Purpose: To investigate the effects of bilberry extract, Difrarel, on form-deprivation myopia in guinea pigs. Method: Thirty healthy pi...
A Prospective Masked Clinical Assessment of Inflammation After Intravitreal Injection of Ranibizumab or Aflibercept [0.03%]
评估雷珠单抗和阿柏西普玻璃体内注射后炎症的前瞻性临床研究
Arshad M Khanani,Gregory L Cohen,Rezi Zawadzki
Arshad M Khanani
Purpose: To compare anterior chamber and vitreous inflammation after intravitreal injection of ranibizumab or aflibercept. Methods: Thi...
Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration [0.03%]
基于多能干细胞和基底物质联合治疗年龄相关性黄斑变性
Britney O Pennington,Dennis O Clegg
Britney O Pennington
Age-related macular degeneration (AMD) is the leading cause of blindness in the western world, which severely decreases the quality of life in the patients and places an economic burden on their families and society. The disease is caused b...